Socioeconomic status and perinatal outcomes in a setting with universal access to essential health care services

Along with the increasing needs of the community, also increasing the need for space to accommodated those needs. With limited space available nowadays, it is not uncommon to change the old buildings' function as a place to meet the social growing need of the space. However, it is must be remembered by architects and interior architects when changing the functions of a space that the old space has its own histories and particular meaning to people who had ever occupied it. Those histories and meanings should be included in the creation of the new function. Article gives and describes elements that need to be known in order to understand the sense of a space, such as drawing plans, scale, proportion, movement, transition and access that embodied in the architecture and interior space. Qualitative methods by literature study is used in the making of this article.

Correction to: The Cedar Project: Using Indigenous-specific determinants of health to predict substance use among young pregnant-involved Indigenous women in Canada

After publication of the original article (1) it was noted that the title of this manuscript was incorrect. The title presently reads “The cedar project: using indigenous-specific determinants of health to predict substance use among young pregnant-involved aboriginal women” but should read “The Cedar Project: Using Indigenous-specific determinants of health to predict substance use among young pregnant-involved Indigenous women in Canada”.Health and Social Development, Faculty of (Okanagan)Medicine, Faculty ofNon UBCNursing, School of (Okanagan)Obstetrics and Gynaecology, Department ofPopulation and Public Health (SPPH), School ofReviewedFacult

Association of co-exposure of antenatal steroid and prophylactic indomethacin with spontaneous intestinal perforation

Objective: to evaluate the association of a combined exposure to antenatal steroids and prophylactic indomethacin with the outcome of spontaneous intestinal perforation (SIP) among neonates born at &lt;26 weeks of gestation or &lt;750 g birth weight.Study design: we conducted a retrospective study of preterm infants admitted to Canadian Neonatal Network units between 2010 and 2018. Infants were classified into 2 groups based on receipt of antenatal steroids; the latter subgrouped as recent (≤7 days before birth) or latent (&gt;7 days before birth) exposures. The co-exposure was prophylactic indomethacin. The primary outcome was SIP. Multivariable logistic regression analysis was used to calculate aORs.Results: among 4720 eligible infants, 4121 (87%) received antenatal steroids and 1045 (22.1%) received prophylactic indomethacin. Among infants exposed to antenatal steroids, those who received prophylactic indomethacin had higher odds of SIP (aOR 1.61, 95% CI 1.14-2.28) compared with no prophylactic indomethacin. Subgroup analyses revealed recent antenatal steroids exposure with prophylactic indomethacin had higher odds of SIP (aOR 1.67, 95% CI 1.15-2.43), but latent antenatal steroids exposure with prophylactic indomethacin did not (aOR 1.24, 95% CI 0.48-3.21), compared with the respective groups with no prophylactic indomethacin. Among those not exposed to antenatal steroids, mortality was lower among those who received prophylactic indomethacin (aOR 0.45, 95% CI 0.28-0.73) compared with no prophylactic indomethacin.Conclusions: in preterm neonates of &lt;26 weeks of gestation or birth weight &lt;750 g, co-exposure of antenatal steroids and prophylactic indomethacin was associated with SIP, especially if antenatal steroids was received within 7 days before birth. Among those unexposed to antenatal steroids, prophylactic indomethacin was associated with lower odds of mortality.</p