2,788 research outputs found
Cap mesenchyme cell swarming during kidney development is influenced by attraction, repulsion, and adhesion to the ureteric tip
Morphogenesis of the mammalian kidney requires reciprocal interactions between two cellular domains at the periphery of the developing organ: the tips of the epithelial ureteric tree and adjacent regions of cap mesenchyme. While the presence of the cap mesenchyme is essential for ureteric branching, how it is specifically maintained at the tips is unclear. Using ex vivo timelapse imaging we show that cells of the cap mesenchyme are highly motile. Individual cap mesenchyme cells move within and between cap domains. They also attach and detach from the ureteric tip across time. Timelapse tracks collected for >800 cells showed evidence that this movement was largely stochastic, with cell autonomous migration influenced by opposing attractive, repulsive and cell adhesion cues. The resulting swarming behaviour maintains a distinct cap mesenchyme domain while facilitating dynamic remodelling in response to underlying changes in the tip
SOOP Network Enhancement Report
Report on the network enhancement project, this will document (a) extension of network coverage to South Atlantic; (b) evaluation of improved EOV carbonate system; and (c) re-assessment of instrumentatio
Size of Outbreaks Near the Epidemic Threshold
The spread of infectious diseases near the epidemic threshold is
investigated. Scaling laws for the size and the duration of outbreaks
originating from a single infected individual in a large susceptible population
are obtained. The maximal size of an outbreak n_* scales as N^{2/3} with N the
population size. This scaling law implies that the average outbreak size
scales as N^{1/3}. Moreover, the maximal and the average duration of an
outbreak grow as t_* ~ N^{1/3} and ~ ln N, respectively.Comment: 4 pages, 5 figure
Is diversity good?
Prominent ethical and policy issues such as affirmative action and female
enrollment in science and engineering revolve around the idea that diversity is
good. However, even though diversity is an ambiguous concept, a precise
definition is seldom provided. We show that diversity may be construed as a
factual description, a craving for symmetry, an intrinsic good, an instrumental
good, a symptom, or a side effect. These acceptions differ vastly in their
nature and properties. The first one cannot lead to any action and the second
one is mistaken. Diversity as intrinsic good is a mere opinion, which cannot be
concretely applied; moreover, the most commonly invoked forms of diversity
(sexual and racial) are not intrinsically good. On the other hand, diversity as
instrumental good can be evaluated empirically and can give rise to policies,
but these may be very weak. Finally, symptoms and side effects are not actually
about diversity. We consider the example of female enrollment in science and
engineering, interpreting the various arguments found in the literature in
light of this polysemy.
Keywords: ethics, policy, higher education, female students, minority
students, affirmative actionComment: 7 page
Circuits in random graphs: from local trees to global loops
We compute the number of circuits and of loops with multiple crossings in
random regular graphs. We discuss the importance of this issue for the validity
of the cavity approach. On the one side we obtain analytic results for the
infinite volume limit in agreement with existing exact results. On the other
side we implement a counting algorithm, enumerate circuits at finite N and draw
some general conclusions about the finite N behavior of the circuits.Comment: submitted to JSTA
Analytical solution of a one-dimensional Ising model with zero temperature dynamics
The one-dimensional Ising model with nearest neighbour interactions and the
zero-temperature dynamics recently considered by Lefevre and Dean -J. Phys. A:
Math. Gen. {\bf 34}, L213 (2001)- is investigated. By introducing a
particle-hole description, in which the holes are associated to the domain
walls of the Ising model, an analytical solution is obtained. The result for
the asymptotic energy agrees with that found in the mean field approximation.Comment: 6 pages, no figures; accepted in J. Phys. A: Math. Gen. (Letter to
the Editor
Treating clinical mastitis in dairy cows with essential oils
Clinical mastitis is the main concern in dairy farming today, but there are very few drugs that are compatible with organic specifications. Our study was conducted in order to evaluate the therapeutic efficiency of the intramammary infusion of three essential oils, Thymus vulgaris, Rosmarinus verbenone and Laurus nobilis. Fifty-five cases of mastitis were treated with 10 ml of a mixture of the three oils (1.5% each in sunflower oil). Forty-five others were treated with 10 ml of a mixture of Thymus vulgaris and Rosmarinus verbenone (6% of each in sunflower oil or in water). The recovery rate was only 40%, which is deemed unsatisfactory
Laser Wire Scanner Compton Scattering Techniques for the Measurement of the Transverse Beam Size of Particle Beams at Future Linear Colliders
This archive summarizes a working paper and conference proceedings related to
laser wire scanner development for the Future Linear Collider (FLC) in the
years 2001 to 2006. In particular the design, setup and data taking for the
laser wire experiments at PETRA II and CT2 are described. The material is
focused on the activities undertaken by Royal Holloway University of London
(RHUL).Comment: 61 page
General relativistic corrections to the Sagnac effect
The difference in travel time of corotating and counter-rotating light waves
in the field of a central massive and spinning body is studied. The corrections
to the special relativistic formula are worked out in a Kerr field. Estimation
of numeric values for the Earth and satellites in orbit around it show that a
direct measurement is in the order of concrete possibilities.Comment: REVTex, accepted for publication on Phys. Rev.
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