Impaired Mental Age Self-Consciousness in Latent Schizophrenia

BACKGROUND: The topic of research was phenomenon of impaired age self-consciousness in non-psychotic latent schizophrenia patients defined. METHODS: The study sample comprised 141 patients with latent schizophrenia (pseudo neurotic (F21.3 - 64.5%, 91 patients), coenesthopathic (F20.8 - 25.5%, 36 patients) and pseudo psychopathic (F21.4 - 9.9%, 14 patients)) aged 16-31 (average 22.1 years old) in 2007-2019. A follow-up, experimental psychological and clinical study was conducted. RESULTS: The onset of impaired age self-identity was dominated by a radical drop of the subjective age in self-conscious mind of the patients accompanied by a tormented feeling of loss of self-dependence, role autonomy, helplessness, inability of decision making and to be answerable. Patients described this sudden condition as a loss of 'maturity feeling' and return to the juvenile perception of self. In a delusive and unclear manner, phrases such as 'I feel inferior to others as if a helpless child among adults', 'I feel as if my childhood is back' were uttered. Excessive worrying and enlivening of childhood memories were also included. This correlates to occurrence of humble and sometimes dependent/avoidant behavior, feeling of helplessness and fear with respect to caring for one self, rising subordination and suggestibility. CONCLUSIONS: This phenomenon of regress to earlier ontogenetic level of personal development reported as impaired age self-consciousness can thus be regarded as an obligate form of depersonalization in patients with latent schizophrenia

ИЗМЕНЕНИЕ КЛИНИЧЕСКОЙ КАРТИНЫ АЛКОГОЛЬНОЙ ЗАВИСИМОСТИ НА ФОНЕ ЛЕЧЕНИЯ НАЛТРЕКСОНОМ ДЛИТЕЛЬНОГО ДЕЙСТВИЯ В ИНЪЕКЦИОННОЙ ФОРМЕ: СЛУЧАЙ ИЗ ПРАКТИКИ

Alcoholism is a severe chronic mental illness, often subordinating all aspects of the patient’s life and quickly leading to social degradation. In recent years we observed a certain change in the attitude towards the classical therapeutic approach, which implies a complete abstention from alcohol intake. This was due to the research on pharmacological agents that can affect the brain reinforcement system, thereby reducing craving and decreasing the amount of alcohol consumed. This article describes a clinical case of changing the pattern of alcohol abuse during the use of opioid receptor antagonist naltrexone in the form of injections for the treatment of a patient with severe alcohol dependence, resistant to psychopharmacotherapy. The effectiveness and duration of the treatment course is determined primarily by patients’ motivation or by the interest of persons close to the patient.В данной статье описан клинический случай применения антагониста опиоидных рецепторов налтрексона пролонгированного действия в форме инъекций для лечения пациента с тяжелым случаем алкогольной зависимости, резистентной к психофармакотерапии. Эффективность и продолжительность курса лечения, определяется в первую очередь, мотивацией больных либо заинтересованностью близких пациенту лиц

Psychosomatics in eating disorders

Background: To study the psychosomatic options and dynamics in patients with eating disorders. To conduct a comparative study of psychosomatic characteristics of surveyed patients with eating disorders, taking into account the duration and severity of protein-energy deficiency and levels of catecholamines excretion; to reveal features of mental working capacity, basic mental processes and EEG data at different stages of eating disorders; to develop scientifically based effective methods and means for correcting pathological changes that have arisen as a result ofprolonged protein-energy deficiency in eating disorders. Methods: Catamnestic, statistical, clinico-psychopathological with somatic, psychological and laboratory examination, anthropometry, high-performance liquid chromatography, electroencephalography. Statistical analysis of collected data was processed using the program IBM SPSS Statistics 22, the confidence level p-value is <0.001. Results: The long-term consequences ofprolonged fasting in 500 women with eating disorders (ED), who applied for help at the RUDN department and were examined in 1987-2013, were studied. The most common somatic complications ofprolonged protein-energy deficiency were investigated. In addition to the clinical method and anthropometry, to measure the efficiency of weight gain after prolonged alimentary deficiencies and to treat anorexia nervosa patients the pathopsychological method of "Shabalina's complex decoding" and analysis of catecholamine excretion rates in urine of patients with anorexia at different stages of therapy were used. Improvement of mental performance and general condition of the examined after applying the developed treatment was observed. Scientifically based principles of therapy, allowing to avoid complications of long-term fasting and during weight gain were suggested. © Medicinska naklada - Zagreb, Croati

ИЗМЕНЕНИЕ КЛИНИЧЕСКОЙ КАРТИНЫ АЛКОГОЛЬНОЙ ЗАВИСИМОСТИ НА ФОНЕ ЛЕЧЕНИЯ НАЛТРЕКСОНОМ ДЛИТЕЛЬНОГО ДЕЙСТВИЯ В ИНЪЕКЦИОННОЙ ФОРМЕ: СЛУЧАЙ ИЗ ПРАКТИКИ

Alcoholism is a severe chronic mental illness, often subordinating all aspects of the patient’s life and quickly leading to social degradation. In recent years we observed a certain change in the attitude towards the classical therapeutic approach, which implies a complete abstention from alcohol intake. This was due to the research on pharmacological agents that can affect the brain reinforcement system, thereby reducing craving and decreasing the amount of alcohol consumed. This article describes a clinical case of changing the pattern of alcohol abuse during the use of opioid receptor antagonist naltrexone in the form of injections for the treatment of a patient with severe alcohol dependence, resistant to psychopharmacotherapy. The effectiveness and duration of the treatment course is determined primarily by patients’ motivation or by the interest of persons close to the patient.В данной статье описан клинический случай применения антагониста опиоидных рецепторов налтрексона пролонгированного действия в форме инъекций для лечения пациента с тяжелым случаем алкогольной зависимости, резистентной к психофармакотерапии. Эффективность и продолжительность курса лечения, определяется в первую очередь, мотивацией больных либо заинтересованностью близких пациенту лиц

Analysis of the Quality of life and the Prevalence of Various Types of Mental Disorders in Patients with Isolated and Combined Somatic Pathology

BACKGROUND: The aim of the work is to compare the characteristics of quality of life and mental disorders in patients in the group with isolated gastroesophageal reflux disease (GERD) and in patients with combined pathology (GERD in combination with hypothyroidism). METHODS: Symptomatic questionnaire of Yu. Alexandrovich and questionnaire SF-36 were used. The survey was conducted in 124 patients aged 18 to 65 years. RESULTS: Anxiety disorders are the most common among the mental disorders in patients with GERD, depressive and psychasthenic disorders - in patients with combined pathology. All indicators of quality of life were lower in patients with combined pathology