Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of and -2

<p><b>Copyright information:</b></p><p>Taken from "Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of and "</p><p>http://www.biomedcentral.com/1471-2156/8/45</p><p>BMC Genetics 2007;8():45-45.</p><p>Published online 3 Jul 2007</p><p>PMCID:PMC1937007.</p><p></p>on. . Side view dimensions of the anterior chamber. D2-eyes show no IPD but have a distinct form of ISA where the iris appears 'roughened'. D2-eyes have no transillumination defects and normal anterior chamber morphology (more than 20 eyes were analyzed from a variety of ages, images shown here are from a 13 months old mouse). . IOP measurements in D2-mice. Individual IOP readings are plotted as circles. The solid horizontal line indicates 21 mmHg, a value considered to be glaucoma-suspect in people. No 'high' IOP readings were seen in 97 eyes measured. Also, there is no significant change in IOP levels comparing 4 months old D2-mice to the 8, 10, 12 or 14 months old groups (p > 0.37 for all comparisons)