Down-regulated cell growth and development- and cell signaling and signal transduction-associated genes in colonic mucosa of senior vs. young adult dogs.

<p>Down-regulated cell growth and development- and cell signaling and signal transduction-associated genes in colonic mucosa of senior vs. young adult dogs.</p

Down-regulated cellular trafficking and protein processing-, immune and stress response-, and transcription-translation-associated genes in hepatic tissue of senior vs. young adult dogs fed an animal protein-based (APB) or plant protein-based (PPB) diet.

<p>Down-regulated cellular trafficking and protein processing-, immune and stress response-, and transcription-translation-associated genes in hepatic tissue of senior vs. young adult dogs fed an animal protein-based (APB) or plant protein-based (PPB) diet.</p

Up-regulated genes in hepatic tissue of senior and young adult dogs fed an animal protein-based (APB) vs. plant protein-based (PPB) diet.

<p>Up-regulated genes in hepatic tissue of senior and young adult dogs fed an animal protein-based (APB) vs. plant protein-based (PPB) diet.</p

Down-regulated cell signaling and signal transduction-, cellular trafficking and protein processing-, and transcription-translation-associated genes in hepatic tissue of young adult dogs fed an animal protein-based (APB) vs. plant protein-based (PPB) diet.

<p>Down-regulated cell signaling and signal transduction-, cellular trafficking and protein processing-, and transcription-translation-associated genes in hepatic tissue of young adult dogs fed an animal protein-based (APB) vs. plant protein-based (PPB) diet.</p

Range map for members of the Suidae.

<p>Range map for members of the Suidae.</p

Heatmap of senior vs. young adult dog pairwise comparisons.

<p>Values are the GCRMA-processed probe set value (Log₂ scale) minus the mean value for that probe set across all arrays. The dendrogram was created by hierarchical cluster analysis.</p

Heatmap of animal-protein based diet (APB) vs. plant-protein based diet (PPB) pairwise comparisons.

<p>Values are the GCRMA-processed probe set value (Log₂ scale) minus the mean value for that probe set across all arrays. The dendrogram was created by hierarchical cluster analysis.</p

Differentially expressed cell growth and development-, cell signaling and signal transduction-, and immune and stress response-associated genes in colonic mucosa of senior and young adult dogs fed an animal protein-based diet vs. plant protein–based diet.

<p>Differentially expressed cell growth and development-, cell signaling and signal transduction-, and immune and stress response-associated genes in colonic mucosa of senior and young adult dogs fed an animal protein-based diet vs. plant protein–based diet.</p

Differentially expressed cellular metabolism and protein processing- and transcription/translation-associated genes in colonic mucosa of senior and young adult dogs fed an animal protein-based diet vs. plant protein–based diet.

<p>Differentially expressed cellular metabolism and protein processing- and transcription/translation-associated genes in colonic mucosa of senior and young adult dogs fed an animal protein-based diet vs. plant protein–based diet.</p

Global view of colonic mucosal gene expression alterations in senior vs. young adult dogs fed an animal protein-based diet (APB) or plant protein-based diet (PPB).

1<p>Values in the parenthesis represent the percentage of gene transcripts differentially expressed in relation to the total number of genes expressed in colon tissue (14,217 genes).</p>2<p>Number of annotated and non-redundant genes that had >1.5 fold-change in gene expression.</p