Arrow injuries to the eye

Two male siblings aged 10 and 17 years, respectively, presented to our hospital with two days history of being shot in the right eyes with arrows. The patients presented with severe pains, bleeding, swelling, discharge and loss of vision. There was positive history of application of traditional eye medicine and an unsuccessful attempt was made to remove the arrows. Both patients presented with panophthalmitis. X-rays of the orbits and para nasal sinuses indicated the tip of the arrow was lodged to the apex of the orbit in the younger patient, and the arrow vertically traverses the eye/ orbit and lodged in the roof of the maxillary sinus in the other patient with fluid level in the lower third of the sinus. The patients were placed on broad-spectrum systemic antibiotics, had base line investigations and prepared for exploration. The patients had evisceration with removal of the arrows

Effects of Allelochemicals of Some Eucalyptus Species on Germination and Radicle Growth of Arachis Hypogea

A laboratory experiment was conducted to assess the effects of allelochemicals of Eucalyptus camaldulensis, Eucalyptus citriodora and Eucalyptus globules on germination and root elongation using leguminous crop ground nut (Arachis hypogea) as bioassay material. The experiments were conducted in sterilized petridishes. The effect of different concentration of aqueous extracts was compared with distilled water (control). The result revealed that different concentrations of E. globulus and E. camaldulensis extracts caused highly significant (p=0.05) inhibitory effect on germination and root elongation. The bioassays indicated that the inhibitory effect was proportional to the concentrations of the extracts so that higher concentration has a stronger inhibitory effect. The study also revealed that inhibitory effect was much pronounced in root development rather than seed germination. Key words: Allelochemicals, Eucalyptus species, Root length, Germination, Arachis hypoge

Inhibition of Germination and Growth Behavior of Some Cowpea Varieties Using Neem (Azadiracta Indica) Leaf Water Extracts

The experiment was conducted to observe the inhibitory effects of the leaf extract derived from neem (Azadiracta indica) on germination and growth behavior of some cowpea varieties (receptor). Experiments were set on sterilized petridishes with a photoperiod of 24 hours at room temperature of 27-30oC. The effects of the different concentrations of aqueous extracts were compared with distilled water (control). The aqueous extracts of leaf caused significant inhibitory effects on germination, root and shoot elongation and development of lateral roots of treated plants. Bioassays indicated that the inhibitory effect was proportional to the concentrations of the extract, as concentration increased the extent of inhibition also increased. The study also revealed that inhibitory effect was much pronounced in root and lateral root development rather than germination and shoot growth.Keywords: Neem, Allelopathic effect, Leaf extract, Germination, Growth behavio

Adapted motivational interviewing to improve the uptake of treatment for glaucoma in Nigeria: study protocol for a randomized controlled trial.

BACKGROUND: Glaucoma is a chronic eye disease associated with irreversible visual loss. In Africa, glaucoma patients often present late, with very advanced disease. One-off procedures, such as laser or surgery, are recommended in Africa because of lack of or poor adherence to medical treatment. However, acceptance of surgery is usually extremely low. To prevent blindness, adherence to treatment needs to improve, using acceptable, replicable and cost-effective interventions. After reviewing the literature and interviewing patients in Bauchi (Nigeria) motivational interviewing (MI) was selected as the intervention for this trial, with adaptation for glaucoma (MIG). MI is designed to strengthen personal motivation for, and commitment to a specific goal by eliciting and exploring a person's reasons for change within an atmosphere of acceptance and compassion. The aim of this study is to assess whether MIG increases the uptake of laser or surgery amongst glaucoma patients where this is the recommended treatment. The hypothesis is that MIG increases the uptake of treatment. This will be the first trial of MI in Africa. METHODS: This is a hospital based, single centre, randomized controlled trial of MIG plus an information sheet on glaucoma and its treatment (the latter being "standard care") compared with standard care alone for glaucoma patients where the treatment recommended is surgery or laser.Those eligible for the trial are adults aged 17 years and above who live within 200 km of Bauchi with advanced glaucoma where the examining ophthalmologist recommends surgery or laser. After obtaining written informed consent, participants will be randomly allocated to MIG plus standard care, or standard care alone. Motivational interviewing will be delivered in Hausa or English by one of two MIG trained personnel. One hundred and fifty participants will be recruited to each arm. The primary outcome is the proportion of participants undergoing laser or surgery within two months of the date given to re attend for the procedure. MIG quality will be assessed using the validated MI treatment integrity scale. DISCUSSION: Motivational interviewing may be an important tool to increase the acceptance of treatment for glaucoma. The approach is potentially scalable and may be useful for other chronic conditions in Africa. TRIAL REGISTRATION: ISRCTN79330571 (Controlled-Trials.com)

Seasonal prevalence of bovine fasciolosis and its direct economic losses (del) due to liver condemnation at Makurdi abattoirs north central Nigeria

This study was conducted to report the prevalence of bovine fasciolosis and to estimate the direct  economic losses (DEL) from condemnation of liver as a result of detection of lesions of fasciolosis in cattle slaughtered in Makurdi abattoirs. Retrospective data were collected from the abattoir records obtained  from Ministry of Agriculture and Natural Resources (MANR) Makurdi, from 2008 to 2012. Direct economic losses were calculated based on a pilot study to determine the average price of liver per kilogram  (AvP/kg) and using the formula: DEL = w × AvP/kg, where is the number of livers condemned and is the average liver weight in kg. Between 2008 and 2012, 64,978 cattle were slaughtered at Makurdi abattoirs, out of which 9,478 cattle were infected with Fasciola species. This represents an overall prevalence of 14.56% (95%, C.I.: 12.99 – 16.85%). Annual prevalence of bovine fasciolosis was  significantly (P <0.05) high in 2010 and decreased from 2011 to 2012. During the late dry season, the  prevalence of bovine fasciolosis was significantly high (P <0.05). A total of 4220 liver were condemned  during the study period. This amounted to 12660 kg and valued at ₦12,660,000.00 ($79251.60 USD). The  highest prevalence was recorded during the late dry season. However, cattle acquire the infection during  the wet season and early dry season. Pathological lesions were much obvious during the late dry season  possibly when the animals were most stressed, hence we suggest that control measures should be  targeted towards wet and early dry seasons. Bovine fasciolosis is prevalent in cattle slaughtered in  Makurdi abattoirs and accounts for huge financial losses.Keywords: Bovine fasciolosis, Economic losses, Makurdi, Prevalence, Seaso

Prevalence and risk factors for diabetes and diabetic retinopathy: results from the Nigeria national blindness and visual impairment survey.

BACKGROUND: In Nigeria, urbanisation and increasing life expectancy are likely to increase the incidence of non-communicable diseases. As the epidemic of diabetes matures, visual loss from diabetic retinopathy (DR) will increase unless mechanisms for early detection and treatment improve, and health systems respond to the growing burden of non-communicable diseases. METHODS: A nationally-representative population-based sample of 13,591 participants aged ≥40 years selected by multistage-stratified-cluster-random-sampling with probability-proportional-to-size procedures were examined in 305 clusters in Nigeria between January 2005 to June 2007. All were asked about history of diabetes and underwent basic eye examination. Visual acuity (VA) was measured using logMAR E-chart. Participants with VA11.1mmol/l or had DR. Data in the subsample were used to estimate the prevalence and to analyse risk factors for diabetes and DR using multivariable logistic regression. Additional information on the types of DR was obtained from participants not in the subsample. RESULTS: In the subsample, 164 participants were excluded due to missing data; and 1,595 analysed. 52/1,595 had diabetes, a prevalence of 3.3% (95%CI 2.5-4.3%); and 25/52(48%) did not know. Media opacity in 8/52 precluded retinal examination. 9/44(20.5%) had DR. Higher prevalence of diabetes was associated with urban residence (Odds ratio [OR]1.87) and overweight/obesity (OR3.02/4.43 respectively). Although not statistically significant, DR was associated with hypertension (OR3.49) and RBG>15.0mmol/L (OR8.10). Persons with diabetes had 3 times greater odds of blindness. Of 11,832 other participants in the study sample, 175(1.5%) had history of diabetes; 28 had DR. Types of DR (total=37) included 10.8% proliferative, 51.4% macular oedema. CONCLUSION: The age-adjusted prevalence of diabetes in Nigeria was 3.25% (95%CI 2.50-4.30) and over 10% of people with diabetes aged ≥40 years had sight-threatening-DR. These data will enable the development of better public health strategies for the control of diabetes and planning services for DR to prevent vision loss