Negative Pressure Wound Therapy Versus Conventional Wound Care In Cancer Surgical Wounds: A Meta-Analysis Of Observational Studies And Randomised Controlled Trials

Abstract The application of negative pressure wound therapy (NPWT) in cancer surgical wounds is still controversial, despite its promising usage, because of the risks of increased tumorigenesis and metastasis. This study aimed to review the risks and benefits of NPWT in surgical wounds with the underlying malignant disease compared with conventional wound care (CWC). The first outcome was wound complications, divided into surgical site infection (SSI), seroma, hematoma, and wound dehiscence. The secondary outcome was hospital readmission. We performed a separate meta-analysis of observational studies and randomised controlled trials (RCTs) with CI 95%. Thirteen observational studies with 1923 patients and seven RCTs with 1091 patients were included. NPWT group showed significant decrease in the risk of SSI (RR = 0.45) and seroma (RR = 0.61) in observational studies with P value <0.05, as well as RCTs but were not significant (RR = 0.88 and RR = 0.68). Wound dehiscence (RR = 0.74 and RR = 1.15) and hospital readmission (RR = 0.90 and RR = 0.62) showed lower risks in NPWT group but were not significant. Hematoma (RR = 1.08 and RR = 0.87) showed no significant difference. NPWT is not contraindicated in cancer surgical wounds and can be considered a beneficial palliative treatment to promote wound healing

Hubungan Merokok Terhadap Angka Kejadian Hipertensi di Poli Jantung RSUD Dr. Soetomo Surabaya Periode 2015-2016

Background: Hypertension or high blood pressure, has now become a global health problem in the cardiovascular field. In Indonesia, hypertension is a serious problem, in addition to the high prevalence, the disease also causes another fatal diseases such as heart disease, stroke, kidney failure and others. Smoking is one of the hypertension risk factors. Objective: The aim of this study is to analyze the association between smoking and hypertension in cardiac outpatient unit of RSUD Dr. Soetomo Surabaya 2015 – 2016 period. Methods: This research is a cross-sectional study using primary data with questionnaires. The amount of subjects was calculated with minimum sampling, in result of 83 respondents. The data was analyzed with Chi-square and Relative Risk test statistics. Results: The result showed a positive association between active and passive smoking with significant value of p=0.033 (p<0.05) and RR=1.565, which means passive smoking increases the risk of hypertension 1,565 times bigger than active smoking. The non-filter type of cigarettes has a value of RR=1.500, which means the incidence rate of hypertension is 1.5 times bigger than the filter type of cigarettes. There is also increased blood pressure as the number and duration of smoking in active smokers increased