Kingdom Compossible

Does God exist? Can we know for sure? What might it mean to know this? Furthermore what might it look like to make works of art while also seeking to find answers to these questions? This thesis details my personal experiences growing up in a world steeped in postmodernism and my move to answer such questions while looking to develop a meaningful, clear worldview and body of work. I have turned my focus on specific episodes in my life, which significantly illuminate a progression of thinking and experience. Together these thoughts and experiences have become the impetus for both questions and propositions embedded within the long haul of my work culminating in my thesis exhibition

Viability Criteria during Liver Ex-Situ Normothermic and Hypothermic Perfusion

With the increased use of extended-criteria donors, machine perfusion became a beneficial alternative to cold storage in preservation strategy for donor livers with the intent to expand donor pool. Both normothermic and hypothermic approach achieved good results in terms of mid- and long-term outcome in liver transplantation. Many markers and molecules have been proposed for the assessment of liver, but no definitive criteria for graft viability have been validated in large clinical trials and key parameters during perfusion still require optimization.In this review, we address the current literature of viability criteria during normothermic and hypothermic machine perfusion and discuss about future steps and evolution of these technologies

Long-Term Socio-Ecological Research in the Biosphere Reserve in Mapimi, Mexico: A Multidimensional Participatory Observatory of Rangeland/Pastoral Systems

Since the creation of the UNESCO Biosphere Reserve Mapimi (BRM) in Mexico 45 years ago, pastoralism has undergone a series of transformations. Upon the arrival of the Spaniards, horse breeding flourished until 1900; thereafter extensive cattle production lasted for six decades. Only recently, farmers have adopted alternative management types for organic meat production. National and international efforts to achieve the Sustainable Development Goals (SDGs) require basic, applied, and participatory research efforts. In the socio-ecological pastoral system BRM, first halophytic ecosystems were examined for their ecohydrological role in rangeland productivity. In 1996, a long-term ecological research site was installed to monitor the effects of herbivores on the composition and biodiversity of desert communities. Shortly thereafter, the National Commission of Natural Protected Areas began a rigorous monitoring and conservation program to guarantee both the sustainable management of natural resources and the sustainable development of reserve dwellers. Soon international multisectoral institutions joined Mexican efforts to protect the natural, cultural, and social diversity of the BRM and to strengthen its socio-ecological resilience to climate change and land degradation. Hence, the BRM is currently a space of participatory monitoring and research, with emphasis on the health of this important socio-ecological pastoralist system. It is examined whether institutional programs promoting organic livestock farming are compatible with this desert system and how biological soil crust is developing as a fundamental indicator of soil functioning and the provision of ecosystem services and human wellbeing. The formation of multisectoral partnerships to foster dryland sustainability have led to the foundation of the International Network for Dryland Sustainability; it is currently coordinating a national network of participatory socio-ecological observatories (PSEOs) to promote the SDGs. Mapimi is one of the first PSEOs to promote local governance and social and ecological sustainable development in the drylands of Mexico and world-wide

From a philosophical framework to a valid prognostic staging system of the new \u201ccomprehensive assessment\u201d for transplantable hepatocellular carcinoma

The comprehensive assessment of the transplantable tumor (TT) proposed and included in the last Italian consensus meeting still deserve validation. All consecutive patients with hepatocellular carcinoma (HCC) listed for liver transplant (LT) between January 2005 and December 2015 were post-hoc classified by the tumor/patient stage as assessed at the last re-staging-time (ReS-time) before LT as follow: high-risk-class (HRC) = stages TTDR, TTPR; intermediate-risk-class (IRC) = TT0NT, TTFR, TTUT; low-risk-class (LRC) = TT1, TT0L, TT0C. Of 376 candidates, 330 received LT and 46 dropped-out. Transplanted patients were: HRC for 159 (48.2%); IRC for 63 (19.0%); LRC for 108 (32.7%). Cumulative incidence function (CIF) of tumor recurrence after LT was 21%, 12%, and 8% at 5-years and 27%, 15%, and 12% at 10-years respectively for HRC, IRC, and LRC (P = 0.011). IRC patients had significantly lower CIF of recurrence after LT if transplanted >2-months from ReS-time (28% vs. 3% for <2 and >2 months, P = 0.031). HRC patients had significantly lower CIF of recurrence after-LT if transplanted <2 months from the ReS-time (10% vs. 33% for <2 and >2 months, P = 0.006). The proposed TT staging system can adequately describe the post-LT recurrence, especially in the LRC and HRC patients. The intermediate-risk-class needs to be better defined and further studies on its ability in defining intention-to-treat survival (ITT) and drop-out are required

Participatory Observatories to Connect Multifunctional Landscapes, Link Smallholder Farmers, and Collectively Diversify Income

Cattle ranching was introduced to Baja California, Mexico (semiarid and arid climates) by the Spaniards, who brought the animals and the techniques. One important activity was moving livestock from the mountains (forests and few kinds of grass) to the coast crossing poor shrublands known as chaparrals. Fire was a common practice to promote grass growth and pastoralists could move through the land freely. Pastoralism became a common practice when English workers built the Ensenada port and became ranching landowners. They followed the practice of livestock movement through the exorreic watersheds. Native Indians, as well as other Mexicans known as ejidatarios, who had access to communal land, and wealthy livestock managers learned the same transhumance practices. They followed them until recently when privatizing the land began fragmenting the rangeland by installing fences; besides insecure places emerged due to illegal crop production. The Guadalupe watershed in Baja California is an interesting place to study rangelands as dynamic socio-ecological systems driven by institutional changes. Its land-use history has provoked interesting questions oriented to enlighten the future of livestock and rangeland management. This talk deals with the project of a citizen\u27s observatory where results from good local land and water management practices are being compiled and presented in a portal for its out-reach. The internet site will also make available scientific papers translated into infographics to make high-quality information accessible. Before and after special techniques like keyline design, holistic management, and other locally adapted techniques are being measured by ranchers and students as a citizen science program. We think that co-monitoring and improving data availability will facilitate local decision-making and deal with the multifunctionality of future rangelands in a better way

Percutaneous Transhepatic Bile Duct Ablation with n-Butyl Cyanoacrylate in the Treatment of a Biliary Complication after Split Liver Transplantation

Biliary complications continue to be a major cause of morbidity after split-liver transplantation (SLT). In this report we describe an uncommon late biliary complication. One year after SLT the patient showed an intrahepatic bile dicy dilatation with severe cholangitis episodes. The segmentary bile duct of hepatic segment VI-VII draining in the left duct was unidentified and tied at the time of the in situ split-liver procedure. We perform a permanent obliteration of the dilated intrahepatic ducts by a percutaneous embolization using an n-butyl cyanoacrylate (NABC). The management of biliary complications after SLT requires a multidisciplinary approach. The use of NBCA in obliteration of a dilated bile duct seems to be a safe procedure with good results providing a less invasive option than hepatic resection and decreasing the morbidity associated with chronic external biliary drainage. Further studies are needed to determine whether this approach is effective and safe and whether it could reduce hospital stay and cost