19 research outputs found
Additional file 1: of Empowering smokers with a web-assisted tobacco intervention to use prescription smoking cessation medications: a feasibility trial
Screenshot of study website (home page). A screenshot of the home page of the study website (stopstudy.ca) during recruitment (July 2009). (PNG 130 KB
Schedule of enrolment interventions and assessments.
*Baseline MRI Scans will be counterbalanced such that participants will be undergoing an abstinence scan and a satiated scan within one week of each other. ** Daily tDCS stimulation over the first 2 weeks. List of abbreviations: MRI = functional magnetic resonance imaging; Eot = end of treatment; PHQ-9 = Patient Health Questionnaire–validated self-completed measure of depressive symptoms mapped on to DSM-IV criteria; QSU-brief = 10-item Questionnaire of Smoking Urges; AUDIT = Alcohol Use Disorders Identification Test; FTND = Fagerstrom Test for Nicotine Dependence; EIS = Eysenck Impulsivity Inventory; SSS = Sensation Seeking Scale; PANAS = Positive and Negative Affect Schedule; State Trait = State Trait Anxiety; POMS = Profile of Mood States.; BOLD = Blood oxygen level dependent signal, functional MRI measure of blood flow; Abs = MRI scan conducted following overnight nicotine abstinence (of at least 10 hours); Sat = MRI scan conducted following nicotine satiety (within 1–2 hours of smoking a cigarette).</p
Adverse events of tDCS and varenicline.
Participants will complete the adverse event list at each study appointment. The list consists of the most common side effects of varenicline and tDCS respectively. Participants can indicate the severity by mild, moderate or severe. (PDF)</p
Biological specimens.
Details of biological specimen collection and the tests used for cotinine and drugs abuse. (PDF)</p
Design for smoking cue reactivity task paradigm (MRI task).
During each MRI scan, participants will be presented images for approximately 7 minutes whilst being asked regarding their cigarette craving in between the blocks. The smoking block will consist of pictures related to smoking whilst the neutral block will have neutral images. Each block will last for 35 seconds for a total of 6 blocks. Blood oxygen level signal will be measured during this task. *Photos were taken from the Geneva Smoking Pictures (Khazaal et al. 2012).</p
Estimated electrical field for tDCS stimulation (using SimNIBs).
Estimated electrical field for tDCS stimulation (using SimNIBs).</p