363 research outputs found

    Participatory Approaches to Slum Upgrading and Poverty Reduction in African Cities

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    Many of Africa’s cities have been neglected for decades in an environment of rapid urbanisation. In particular, the inadequate housing conditions within slum areas increasingly do not match the needs of slum dwellers and have contributed to increased levels of poverty. Not only are improvements required to address the ‘backlog of urban neglect’ experienced by the majority of cities, but they are also required to meet the needs of the millions of newcomers expected to arrive over the next few decades. As such, there has been an increasing realisation that urgent solutions are required, especially through participatory programmes. This paper attempts to make a strong argument for these programmes by comparing the effects on poverty of a recent participatory project in Kenya, the BIB:PUP project, with one that has been non-participatory, the KENSUP programme. However, the evidence suggests that participatory programmes currently do not contribute meaningfully to poverty reduction in African cities as they are still implemented on too small a scale. They also face numerous challenges and limitations. Nonetheless, this paper argues that participatory programmes do result in improvements for communities and that there is a large potential for poverty reduction through scaling these up to city level

    Inside Front and Back Covers: Scene Design for Godspell and Noises Off

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    The efficacy of a behavioral activation intervention among depressed US Latinos with limited English language proficiency: study protocol for a randomized controlled trial

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    Major depressive disorder is highly prevalent among Latinos with limited English language proficiency in the United States. Although major depressive disorder is highly treatable, barriers to depression treatment have historically prevented Latinos with limited English language proficiency from accessing effective interventions. The project seeks to evaluate the efficacy of behavioral activation treatment for depression, an empirically supported treatment for depression, as an intervention that may address some of the disparities surrounding the receipt of efficacious mental health care for this population. Following a pilot study of behavioral activation treatment for depression with 10 participants which yielded very promising results, the current study is a randomized control trial testing behavioral activation treatment for depression versus a supportive counseling treatment for depression. We are in the process of recruiting 60 Latinos with limited English language proficiency meeting criteria for major depressive disorder according to the Diagnostic and Statistical Manual of Mental Disorders 4th and 5th Edition for participation in a single-center efficacy trial. Participants are randomized to receive 10 sessions of behavioral activation treatment for depression (n = 30) or 10 sessions of supportive counseling (n = 30). Assessments occur prior to each session and at 1 month after completing treatment. Intervention targets include depressive symptomatology and the proposed mechanisms of behavioral activation treatment for depression: activity level and environmental reward. We will also examine other factors related to treatment outcome such as treatment adherence, treatment satisfaction, and therapeutic alliance. This randomized controlled trial will allow us to determine the efficacy of behavioral activation treatment for depression in a fast-growing, yet highly underserved population in US mental health services. The study is also among the first to examine the effect of the proposed mechanisms of change of behavioral activation treatment for depression (that is, activity level and environmental reward) on depression over time. To our knowledge, this is the first randomized controlled trial to compare an empirical-supported treatment to a control supportive counseling condition in a sample of depressed, Spanish-speaking Latinos in the United States.https://doi.org/10.1186/1745-6215-15-23

    Supporting community energy development in Malawi : a scoping study for the Scottish Government

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    The Scotland and Malawi Co-operation Agreement sets out the ways in which the respective country’s governments engage and work with each other. Key elements of the Co-operation Agreement include regular discussion, learning and expertise exchange between the countries, and a Scottish Government (SG) financed International Development Fund, which supports discrete projects within Malawi. Under the auspices of the Co-operation Agreement, Ministerial discussion during the UN Climate Change Summit in Cancun in December 2010 highlighted the Government of Malawi’s target of increasing electricity access in Malawi from 8% to 15% of the population by 2015. It was agreed that the SG would consider how best it could contribute to this ambition through the Co-operation Agreement’s existing mechanisms. Against this background, the following scoping study was commissioned by the SG. The study commences with an overview of the broad energy and electricity sectors in Malawi, but its specific purpose is to understand how off-grid, community-level renewable energy technology can contribute towards meeting Malawi’s energy needs. To an extent, the scoping study also has its roots in one of the first projects to be supported through the SG’s International Development Fund. The University of Strathclyde-led Community Rural Electrification and Development (CRED) project aimed to improve the sustainability of rural solar panel deployments in Malawi by focussing on community engagement and empowerment, local responsibility and income generation. Learning captured through the project indicated that, aside from the obvious energy provision, community-level generation had the potential to bring considerable socio-economic benefits to rurally isolated Malawians. Given this grounding and experience, the SG invited the University of Strathclyde to lead this scoping study

    Discrepancy between how children perceive their own alcohol risk and how they perceive alcohol risk for other children longitudinally predicts alcohol use

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    This paper examined discrepancies between children's self-perceptions of the riskiness of alcohol use versus their perceptions of the riskiness of alcohol use for other children, and whether these discrepancies predicted children's future alcohol use. Participants included 234 children (M=11 years, 45.3% female) who completed baseline and one-year follow-up assessments on self-perceived riskiness of alcohol use, perceived riskiness of alcohol use for other same-age children, and own past year alcohol use. When considering child age and gender, baseline alcohol use, and the individual reports of the riskiness of alcohol use, the interaction between alcohol use riskiness reports prospectively predicted greater odds of alcohol use. The highest percentage of childhood alcohol use at one-year follow-up came from those children with both low self-perceived riskiness of alcohol use and high perceived riskiness of alcohol use for other children. Children's perceptions of multiple people's risk from alcohol use result in identifying important subgroups of children at risk for early-onset alcohol use.This work was supported, in part, by National Institutes of Health (NIH) grant R01DA18647 (awarded to C. W. Lejuez). NIH had no role in the study design, collection, analysis or interpretation of the data, writing the manuscript, or the decision to submit the paper for publication

    Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity

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    The secretome of cancer and stromal cells generates a microenvironment that contributes to tumour cell invasion and angiogenesis. Here we compare the secretome of human mammary normal and cancer-associated fibroblasts (CAFs). We discover that the chloride intracellular channel protein 3 (CLIC3) is an abundant component of the CAF secretome. Secreted CLIC3 promotes invasive behaviour of endothelial cells to drive angiogenesis and increases invasiveness of cancer cells both in vivo and in 3D cell culture models, and this requires active transglutaminase-2 (TGM2). CLIC3 acts as a glutathione-dependent oxidoreductase that reduces TGM2 and regulates TGM2 binding to its cofactors. Finally, CLIC3 is also secreted by cancer cells, is abundant in the stromal and tumour compartments of aggressive ovarian cancers and its levels correlate with poor clinical outcome. This work reveals a previously undescribed invasive mechanism whereby the secretion of a glutathione-dependent oxidoreductase drives angiogenesis and cancer progression by promoting TGM2-dependent invasion

    The role of gender and race in the relation between adolescent distress tolerance and externalizing and internalizing psychopathology

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    Distress tolerance (DT) is an established construct contributing to the onset and maintenance of psychopathology in adulthood; however, few studies have examined the role of DT in older adolescent psychopathology. Emerging data suggest that gender and race may influence this relation. Therefore, the current study examined the relation between gender, race, and DT on parent-reported internalizing and externalizing DSM-oriented symptoms among a community sample of 128, 14 to 18 year old adolescents. Results indicated a moderating effect of gender on affective problems, such that females with low DT, but not males, displayed significantly greater affective problems. Findings also indicated a significant moderating effect of race, such that Caucasians with low DT, but not African Americans, displayed significantly higher somatic, oppositional defiant, and conduct problems. These findings suggest that DT is an important clinical variable in older adolescence, particularly among Caucasians and females

    Positive and Negative Reinforcement Underlying Risk Behavior in Early Adolescents

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    This version of the article has been accepted for publication, after peer review and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s11121-010-0172-7The goal of the current study was to examine the combined influence of positive reinforcement processes using a behavioral task measuring risk taking propensity (RTP) and negative reinforcement processes using a behavioral task measuring deficits in distress tolerance (DT) on a range of risk taking behaviors among early adolescents. Participants included a community sample of 230 early adolescents (aged 9–13) who completed two behavioral tasks assessing reinforcement processes as well as reported on past year risk behavior involvement as assessed by items from the Youth Risk Behavior Surveillance System at a baseline and a 1-year follow-up assessment. Data indicated that at the Wave 2 assessment, RTP was positively related to number of risk-taking behaviors in the past year but only for those with low DT, with this finding persisting after controlling for the significant influence of male gender and higher sensation seeking. Results of the present study highlight the importance of considering both positive and negative reinforcement processes in combination when investigating vulnerability factors for early risk behavior engagement in youth.https://doi.org/10.1007/s11121-010-0172-

    'Being in Being': Contesting the Ontopolitics of Indigeneity Today

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    This article critiques the shift towards valorizing indigeneity in western thought and contemporary practice. This shift in approach to indigenous ways of knowing and being, historically derided under conditions of colonialism, is a reflection of the ‘ontological turn’ in anthropology. Rather than indigenous peoples simply having an inferior or different understanding of the world to a modernist one, the ‘ontological turn’ suggests their importance is that they constitute different worlds, and that they ‘world’ in a performatively different way. The radical promise is that a different world already exists in potentia and that access to this alternative world is a question of ontology - of being differently: being in being rather than thinking, acting and ‘worlding’ as if we were transcendent or ‘possessive’ subjects. We argue that ontopolitical arguments for the superiority of indigenous ways of being should not be seen as radical or emancipatory resistances to modernist or colonial epistemological and ontological legacies but instead as a new form of neoliberal governmentality, cynically manipulating critical, postcolonial and ecological sensibilities for its own ends. Rather than ‘provincialising’ dominant western hegemonic practices, discourses of ‘indigeneity’ are functioning to extend them, instituting new forms of governing through calls for adaptation and resilience

    A call to action for Universal Health Coverage – Why we need to address gender inequities in the Neglected Tropical Diseases community

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    The UN’s Sustainable Development Goals (SDGs) and pledge to leave no one behind have raised the importance of ensuring equitable health outcomes and healthcare delivery. Multisectoral approaches to tackling neglected tropical diseases (NTDs), including prevention, diagnosis, treatment, and healthcare, have had a limited focus on gender. Yet, gender roles and relations shape vulnerability to NTDs, access to prevention and treatment, and experience of living with NTDs [1]. Understanding the similarities and differences of disease vulnerability and experience between genders can support NTD actors to deliver equitable prevention, diagnosis, and treatment services. The NTD community, including researchers and practitioners, needs to better understand these dynamics and take action to advance gender equality, meet the NTD roadmap 2020 goals, and contribute towards the SDGs and universal health coverage (UHC). The UHC movement is advocating for clear action to address the gender determinants of health. This viewpoint synthesizes evidence from a discussion paper [2] developed by the UN Development Programme (UNDP) and TDR (Special Programme for Research and Training in Tropical Diseases sponsored by UNICEF, UNDP, World Bank, and WHO) in partnership with the Liverpool School of Tropical Medicine to support governments and nongovernment organizations to understand how to recognize and address gender inequities within NTD programs and improve delivery through gender analysis
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