A Novel Adaptive Noise Elimination Algorithm in Long RR Interval Sequences for Heart Rate Variability Analysis

As heart rate variability (HRV) studies become more and more prevalent in clinical practice, one of the most common and significant causes of errors is associated with distorted RR interval (RRI) data acquisition. The nature of such artifacts can be both mechanical as well as software based. Various currently used noise elimination in RRI sequences methods use filtering algorithms that eliminate artifacts without taking into account the fact that the whole RRI sequence time cannot be shortened or lengthened. Keeping that in mind, we aimed to develop an artifacts elimination algorithm suited to long-term (hours or days) sequences that does not affect the overall structure of the RRI sequence and does not alter the duration of data registration. An original adaptive smart time series step-by-step analysis and statistical verification methods were used. The adaptive algorithm was designed to maximize the reconstruction of the heart-rate structure and is suitable for use, especially in polygraphy. The authors submit the scheme and program for use

Ambulatory and successive home-based heart rate targeted aerobic training improves arterial parameters: a follow-up study in people with metabolic syndrome

Background: studies demonstrated that outpatient aerobic exercise programs (aeP) can significantly decrease aortic stiffness in people with metabolic syndrome (Mets). there is some limited data that remotely supervised home-based aeP can also improve arterial stiffness in this population. We aimed to evaluate the changes in the arterial wall parameters after the 2-month ambulatory supervised aeP followed by the 6-month home-based aeP with and without targeting of heart rate (hR) by electrocardiogram (ecG) in people with Mets.Methods: in this prospective study (clinicaltrials.gov identifier: Nct05592704) 132 Mets subjects (mean age 52.44 ± 6.26 years, 54.55% female) were evaluated. at first, all subjects participated in the 2-month ambulatory supervised aeP, which consisted of 40 individual aerobic training sessions on a cycle ergometer 5 times/week for 40 min and received the recommendations for home-based training. then the study (n = 66) and the control (n = 66) groups participated in the 6-month home-based aeP, but only the study group subjects targeted their hR using ecG monitor connected to the smartphone during workouts. arterial stiffness parameters and carotid artery intima-media thickness (ciMt) were evaluated in all participants at baseline and after 8 months.Results: after 8 months, carotid-femoral pulse wave velocity (c-f PWV) significantly reduced in both groups (−12.22% in the study group vs. −7.85% in the control group, all p 7.90 m/s). a significant decrease of 3.32% in ciMt was present only in the study group (p = .032, d = −0.288).Conclusions: the combination of 2-month ambulatory supervised aeP and successive 6-month home-based aeP targeted by hR monitoring using ecG improved arterial properties in Metssubjects more than the same combination without hR targeting, leading to the greater reduction of c-r PWV and ciM

Daily heart rate variability indices in subjects with and without metabolic syndrome before and after the elimination of the influence of day‐time physical activity

Background and Objectives: The available research shows conflicting data on the heart rate variability (HRV) in metabolic syndrome (MetS) subjects. The discrepancy suggests a methodical shortcoming: due to the influence of physical activity, the standard measuring of HRV at rest is not comparable with HRV assessment based on 24h Holter monitoring, which is preferred because of its comprehensiveness. To obtain a more reliable measure and to clarify to what extent HRV is altered in MetS, we assessed a 24h HRV before and after the elimination of the influence of physical activity. Materials and Methods: We investigated 69 metabolic syndrome (MetS) and 37 control subjects, aged 50–55. In all subjects, 24h monitoring of electrocardiogram, blood pressure, and actigraphy profiles were conducted. To eliminate the influence of day-time physical activity on RR intervals (RRI), a linear polynomial autoregressive model with exogenous terms (ARX) was used. Standard spectral RRI analysis was performed. Results: Subjects with MetS had blunted HRV; the diurnal SDNN index was reliably lower in the MetS group than in control subjects. The elimination of the influence of physical activity did not reveal a significant HRV change in long-term indices (SDNN, SDANN, and SD2), whilst adjacent RRI values (RMSSD, pNN50, and SD1) and SDNN index significantly increased (p < 0.001). An increase in the latter indices highlighted the HRV difference between the MetS and control groups; a significant (p < 0.001) decrease of all short-term HRV variables was found in the MetS group (p < 0.01), and low-frequency spectral components were less pronounced in the MetS group. Conclusion: The application of a polynomial autoregressive model in 24h HRV assessment allowed for the exclusion of the influence of physical activity and revealed that MetS is associated with blunted HRV, which reflects mitigated parasympathetic tone