Antiproton-deuteron annihilation at low energies

Recent experimental studies of the antiproton-deuteron system at low energies have shown that the imaginary part of the antiproton-deuteron scattering length is smaller than the antiproton-proton one. Two- and three-body systems with strong annihilation are investigated and a mechanism explaining this unexpected relation between the imaginary parts of the scattering lengths is proposed.Comment: 6 pages, 3 figures, to be published in The European Physical Journal

Inhibition of Interleukin-1-Induced Effects in Synoviocytes Transduced with the Human IL-1 Receptor Antagonist cDNA Using an Adenoviral Vector

Overview summary Adenovirus-mediated gene transfer into the cells of the synovial membrane may provide a means to deliver therapeutically active proteins for the local modification of the immune response in inflammatory arthropathies. In this study, we infected type B human synoviocytes in vitro and rabbit synovial lining membrane in vivo with a recombinant human adenovirus containing the cDNA for the human interleukin-1 receptor antagonist protein (IL-1ra). Expression of human IL-1ra was observed both in the transduced synoviocytes in vitro and in the microenvironment of the transduced rabbit synovial membrane in vivo, and the functional activity of the transgenic IL-1ra was suggested by in vitro inhibition of interleukin-1 (IL-1)-induced prostaglandin E2 (PGE2) production and by in vivo inhibition of IL-1-induced glycosaminoglycan (GAG) degradation.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/63124/1/hum.1995.6.3-307.pd

Discovery Investigative Group (DIG) Report, December 2016

This report is a response to the following charge from project sponsor DeeAnn Allison: Develop a working definition of the purpose and scope for a discovery tool that includes a description of what it should accomplish. How will it help scholars connect with information? The charge included a request to answer seven questions: 1. What content should be included and why? 2. What functions or search capabilities should be included? 3. What social media enhancements should be included? 4. How can it be structured to help both novice and advanced researchers? 5. Can you identify a “perfect” tool? If not, which ones are better and why? 6. Should we abandon Encore? Why or Why not? 7. What is the relation, or non-relation to Google products? Is a discovery tool just a variation of Google? Should it be? Over the course of the Fall 2016 semester, DIG committee members, comprised of seven Libraries faculty who voluntarily participated, met frequently to discuss the charge and determine how to best answer each question. Our answers were ultimately informed through a combination of reviewing the current literature, investigating peer institutions’ search tools, soliciting feedback from our library colleagues through a library-wide survey, and the committee members’ own insights. The responses to each of the following questions are a reflection of the consensus of the DIG committee members

Discovery Investigative Group (DIG) Report, December 2016

This report is a response to the following charge from project sponsor DeeAnn Allison: Develop a working definition of the purpose and scope for a discovery tool that includes a description of what it should accomplish. How will it help scholars connect with information? The charge included a request to answer seven questions: 1. What content should be included and why? 2. What functions or search capabilities should be included? 3. What social media enhancements should be included? 4. How can it be structured to help both novice and advanced researchers? 5. Can you identify a “perfect” tool? If not, which ones are better and why? 6. Should we abandon Encore? Why or Why not? 7. What is the relation, or non-relation to Google products? Is a discovery tool just a variation of Google? Should it be? Over the course of the Fall 2016 semester, DIG committee members, comprised of seven Libraries faculty who voluntarily participated, met frequently to discuss the charge and determine how to best answer each question. Our answers were ultimately informed through a combination of reviewing the current literature, investigating peer institutions’ search tools, soliciting feedback from our library colleagues through a library-wide survey, and the committee members’ own insights. The responses to each of the following questions are a reflection of the consensus of the DIG committee members

Prenormative verification and validation of a protocol for measuring magnetite-maghemite ratios in magnetic nanoparticles

An important step in establishing any new metrological method is a prenormative interlaboratory study, designed to verify and validate the method against its stated aims. Here, the 57Fe Mössbauer spectrometric 'centre of gravity' (COG) method was tested as a means of quantifying the magnetite/maghemite (Fe3O4/γ-Fe2O3) composition ratio in biphasic magnetic nanoparticles. The study involved seven laboratories across Europe and North and South America, and six samples—a verification set of three microcrystalline mixtures of known composition, and a validation set of three nanoparticle samples of unknown composition. The spectra were analysed by each participant using in-house fitting packages, and ex post facto by a single operator using an independent package. Repeatability analysis was performed using Mandel's h statistic and modified Youden plots. It is shown that almost all (83/84) of the Mandel h statistic values fall within the 0.5% significance level, with the one exception being borderline. Youden-based pairwise analysis indicates the dominance of random uncertainties; and in almost all cases the data analysis phase is only a minor contributor to the overall measurement uncertainty. It is concluded that the COG method is a robust and promising candidate for its intended purpose

Fluid observers and tilting cosmology

We study perfect fluid cosmological models with a constant equation of state parameter $\gamma$ in which there are two naturally defined time-like congruences, a geometrically defined geodesic congruence and a non-geodesic fluid congruence. We establish an appropriate set of boost formulae relating the physical variables, and consequently the observed quantities, in the two frames. We study expanding spatially homogeneous tilted perfect fluid models, with an emphasis on future evolution with extreme tilt. We show that for ultra-radiative equations of state (i.e., $\gamma>4/3$), generically the tilt becomes extreme at late times and the fluid observers will reach infinite expansion within a finite proper time and experience a singularity similar to that of the big rip. In addition, we show that for sub-radiative equations of state (i.e., $\gamma < 4/3$), the tilt can become extreme at late times and give rise to an effective quintessential equation of state. To establish the connection with phantom cosmology and quintessence, we calculate the effective equation of state in the models under consideration and we determine the future asymptotic behaviour of the tilting models in the fluid frame variables using the boost formulae. We also discuss spatially inhomogeneous models and tilting spatially homogeneous models with a cosmological constant

Full coherent control of nuclear spins in an optically pumped single quantum dot

Highly polarized nuclear spins within a semiconductor quantum dot (QD) induce effective magnetic (Overhauser) fields of up to several Tesla acting on the electron spin or up to a few hundred mT for the hole spin. Recently this has been recognized as a resource for intrinsic control of QD-based spin quantum bits. However, only static long-lived Overhauser fields could be used. Here we demonstrate fast redirection on the microsecond time-scale of Overhauser fields of the order of 0.5 T experienced by a single electron spin in an optically pumped GaAs quantum dot. This has been achieved using full coherent control of an ensemble of 10^3-10^4 optically polarized nuclear spins by sequences of short radio-frequency (rf) pulses. These results open the way to a new class of experiments using rf techniques to achieve highly-correlated nuclear spins in quantum dots, such as adiabatic demagnetization in the rotating frame leading to sub-micro K nuclear spin temperatures, rapid adiabatic passage, and spin squeezing