Présentation et mise en place du premier système de dialyse péritonéale automatisée connecté en France

The first system of connected automated peritoneal dialysis (APD) was set up in France in the CHSF. This system allows to collect and transmit the data of APD sessions via a modem and a platform towards the medical team and permits the remote adaptation of the treatments. This implementation required a number of steps on national and regional levels. We present the functioning and the expected benefits of such a system.Le premier système connecté de dialyse péritonéale automatisée (DPA) a été mis en place en France au CHSF. Il s’agit d’un système collectant les données des séances de DPA via un modem et une plateforme sécurisée puis les transmettant vers l’équipe médicale et permettant l’adaptation des traitements à distance. Cette mise en place a nécessité un certain nombre de démarches à l’échelle nationale et régionale. Nous en présentons le fonctionnement et les bénéfices attendus. Cette revue est mise à disposition selon les termes de la Licence Creative Commons Attribution 4.0 International

Sotrovimab therapy elicits antiviral activities against Omicron BQ.1.1 and XBB.1.5 in sera of immunocompromised patients [letter]

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Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients

International audienceThe aim of this study was to estimate the incidence of COVID-19 disease in the French national population of dialysis patients, their course of illness and to identify the risk factors associated with mortality. Our study included all patients on dialysis recorded in the French REIN Registry in April 2020. Clinical characteristics at last follow-up and the evolution of COVID-19 illness severity over time were recorded for diagnosed cases (either suspicious clinical symptoms, characteristic signs on the chest scan or a positive reverse transcription polymerase chain reaction) for SARS-CoV-2. A total of 1,621 infected patients were reported on the REIN registry from March 16th, 2020 to May 4th, 2020. Of these, 344 died. The prevalence of COVID-19 patients varied from less than 1% to 10% between regions. The probability of being a case was higher in males, patients with diabetes, those in need of assistance for transfer or treated at a self-care unit. Dialysis at home was associated with a lower probability of being infected as was being a smoker, a former smoker, having an active malignancy, or peripheral vascular disease. Mortality in diagnosed cases (21%) was associated with the same causes as in the general population. Higher age, hypoalbuminemia and the presence of an ischemic heart disease were statistically independently associated with a higher risk of death. Being treated at a selfcare unit was associated with a lower risk. Thus, our study showed a relatively low frequency of COVID-19 among dialysis patients contrary to what might have been assumed