Analytical studies of nuclear light bulb engine radiant heat transfer and performance characteristics

Analytical model of nuclear light bulb engine radiant heat transfer and engine performance, dynamics and control, heat loads and shutdown characteristic

Analytical study of hydrogen turbopump cycles for advanced nuclear rockets Progress report, Sep. 15, 1964 - Sep. 15, 1965

Hydrogen turbopump cycles for obtaining high engine inlet pressures in advanced nuclear rockets, and data on gaseous nuclear reactors and heavy gas containmen

Studies of nuclear light bulb start-up conditions and engine dynamics

Deep Space Network for two-way communications with unmanned spacecraft at planetary distances - Vol.

Endothelial HO-1 induction by model TG-rich lipoproteins is regulated through a NOX4-Nrf2 pathway

Circulating levels of chylomicron remnants (CMRs) increase postprandially and their composition directly reflects dietary lipid intake. These TG-rich lipoproteins likely contribute to the development of endothelial dysfunction, albeit via unknown mechanisms. Here, we investigated how the FA composition of CMRs influences their actions on human aortic endothelial cells (HAECs) by comparing the effects of model CMRs—artificial TG-rich CMR-like particles (A-CRLPs)—containing TGs extracted from fish, DHA-rich algal, corn, or palm oils. HAECs responded with distinct transcriptional programs according to A-CRLP TG content and oxidation status, with genes involved in antioxidant defense and cytoprotection most prominently affected by n-3 PUFA-containing A-CRLPs. These particles were significantly more efficacious inducers of heme oxygenase-1 (HO-1) than n-6 PUFA corn or saturated FA-rich palm CRLPs. Mechanistically, HO-1 induction by all CRLPs requires NADPH oxidase 4, with PUFA-containing particles additionally dependent upon mitochondrial reactive oxygen species. Activation of both p38 MAPK and PPARβ/δ culminates in increased nuclear factor erythroid 2-related factor 2 (Nrf2) expression/nuclear translocation and HO-1 induction. These studies define new molecular pathways coupling endothelial cell activation by model CMRs with adaptive regulation of Nrf2-dependent HO-1 expression and may represent key mechanisms through which dietary FAs differentially impact progression of endothelial dysfunction

High-fat meals rich in EPA plus DHA compared with DHA only have differential effects on postprandial lipemia and plasma 8-isoprostane F-2 alpha concentrations relative to a control high-oleic acid meal: a randomized controlled trial

Background: Eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) supplementation has beneficial cardiovascular effects, but postprandial influences of these individual fatty acids are unclear. Objectives: The primary objective was to determine the vascular effects of EPA + DHA compared with DHA only during postprandial lipemia relative to control high–oleic acid meals; the secondary objective was to characterize the effects of linoleic acid–enriched high-fat meals relative to the control meal. Design: We conducted a randomized, controlled, double-blind crossover trial of 4 high-fat (75-g) meals containing 1) high–oleic acid sunflower oil (HOS; control), 2) HOS + fish oil (FO; 5 g EPA and DHA), 3) HOS + algal oil (AO; 5 g DHA), and 4) high–linoleic acid sunflower oil (HLS) in 16 healthy men (aged 35–70 y) with higher than optimal fasting triacylglycerol concentrations (mean ± SD triacylglycerol, 1.9 ± 0.5 mmol/L). Results: Elevations in triacylglycerol concentration relative to baseline were slightly reduced after FO and HLS compared with the HOS control (P < 0.05). The characteristic decrease from baseline in plasma nonesterified fatty acids after a mixed meal was inhibited after AO (Δ 0–3 h, P < 0.05). HLS increased the augmentation index compared with the other test meals (P < 0.05), although the digital volume pulse–reflection index was not significantly different. Plasma 8-isoprostane F(2α) analysis revealed opposing effects of FO (increased) and AO (reduced) compared with the control (P < 0.05). No differences in nitric oxide metabolites were observed. Conclusions: These data show differential postprandial 8-isoprostane F(2α) responses to high-fat meals containing EPA + DHA–rich fish oil compared with DHA-rich AO, but these differences were not associated with consistent effects on postprandial vascular function or lipemia. More detailed analyses of polyunsaturated fatty acid–derived lipid mediators are required to determine possible divergent functional effects of single meals rich in either DHA or EPA. This trial was registered at clinicaltrials.gov as NCT01618071

Line Broadening in Field Metal-poor Red Giant and Red Horizontal Branch Stars

We report 349 radial velocities for 45 metal-poor field red giant and red horizontal branch stars. We have have identified one new spectroscopic binary, HD 4306, and one possible such system, HD 184711. We also report 57 radial velocities for 11 of the 91 stars reported on previously by Carney et al. (2003). As was found in the previous study, radial velocity "jitter" is present in many of the most luminous stars. Excluding stars showing spectroscopic binary orbital motion, all 7 of the red giants with M(V) <= -2.0 display jitter, as well as 3 of the 14 stars with -2.0 <= M(V) <= -1.4. We have also measured line broadening in all of the new spectra, using synthetic spectra as templates. The most luminous red giants show significant line broadening, as do many of the red horizontal branch stars, and we discuss briefly possible causes.Comment: To appear in the Astronomical Journa

Acoustic tests of duct-burning turbofan jet noise simulation

The results of a static acoustic and aerodynamic performance, model-scale test program on coannular unsuppressed and multielement fan suppressed nozzle configurations are summarized. The results of the static acoustic tests show a very beneficial interaction effect. When the measured noise levels were compared with the predicted noise levels of two independent but equivalent conical nozzle flow streams, noise reductions for the unsuppressed coannular nozzles were of the order of 10 PNdB; high levels of suppression (8 PNdB) were still maintained even when only a small amount of core stream flow was used. The multielement fan suppressed coannular nozzle tests showed 15 PNdB noise reductions and up to 18 PNdB noise reductions when a treated ejector was added. The static aerodynamic performance tests showed that the unsuppressed coannular plug nozzles obtained gross thrust coefficients of 0.972, with 1.2 to 1.7 percent lower levels for the multielement fan-suppressed coannular flow nozzles. For the first time anywhere, laser velocimeter velocity profile measurements were made on these types of nozzle configurations and with supersonic heated flow conditions. Measurements showed that a very rapid decay in the mean velocity occurs for the nozzle tested

Acoustic tests of duct-burning turbofan jet noise simulation: Comprehensive data report. Volume 2: Model design and aerodynamic test results

The selection procedure is described which was used to arrive at the configurations tested, and the performance characteristics of the test nozzles are given

Speckle Interferometry of Metal-Poor Stars in the Solar Neighborhood. I

We report the results of speckle-interferometric observations of 109 high proper-motion metal-poor stars made with the 6-m telescope of the Special Astrophysical Observatory of the Russian Academy of Sciences. We resolve eight objects -- G102-20, G191-55, BD+19$^\circ$~1185A, G89-14, G87-45, G87-47, G111-38, and G114-25 -- into individual components and we are the first to astrometrically resolve seven of these stars. New resolved systems included two triple (G111-38, G87-47) and one quadruple (G89-14) star. The ratio of single-to-binary-to-triple-to-quadruple systems among the stars of our sample is equal to 71:28:6:1.Comment: 8 pages, 4 figures, accepted to Astrophysical Bulleti

Analytical studies of start-up and dynamic response characteristics of the nuclear light bulb engine

Computerized simulation of control systems for nuclear light bulb engine during start-up and at nominal full power operatio