Efficient operation of a high-power X-band gyroklystron

Experimental studies of amplification in a two-cavity X-band gyroklystron are reported. The system utilizes a thermionic magnetron injection gun at voltages up to 440 kV and currents up to 190 A in 1-μs pulses. Optimum performance is achieved by tapering the magnetic-field profile. Peak powers of 20 MW in the TE01 mode at 9.87 GHz are measured with calibrated crystals and with methanol calorimetry. Resultant efficiencies are in excess of 31% and large-signal gains surpass 26 dB. The experimental results are in good agreement with simulated results from a partially self-consistent, nonlinear, steady-state code

Endothelial HO-1 induction by model TG-rich lipoproteins is regulated through a NOX4-Nrf2 pathway

Circulating levels of chylomicron remnants (CMRs) increase postprandially and their composition directly reflects dietary lipid intake. These TG-rich lipoproteins likely contribute to the development of endothelial dysfunction, albeit via unknown mechanisms. Here, we investigated how the FA composition of CMRs influences their actions on human aortic endothelial cells (HAECs) by comparing the effects of model CMRs—artificial TG-rich CMR-like particles (A-CRLPs)—containing TGs extracted from fish, DHA-rich algal, corn, or palm oils. HAECs responded with distinct transcriptional programs according to A-CRLP TG content and oxidation status, with genes involved in antioxidant defense and cytoprotection most prominently affected by n-3 PUFA-containing A-CRLPs. These particles were significantly more efficacious inducers of heme oxygenase-1 (HO-1) than n-6 PUFA corn or saturated FA-rich palm CRLPs. Mechanistically, HO-1 induction by all CRLPs requires NADPH oxidase 4, with PUFA-containing particles additionally dependent upon mitochondrial reactive oxygen species. Activation of both p38 MAPK and PPARβ/δ culminates in increased nuclear factor erythroid 2-related factor 2 (Nrf2) expression/nuclear translocation and HO-1 induction. These studies define new molecular pathways coupling endothelial cell activation by model CMRs with adaptive regulation of Nrf2-dependent HO-1 expression and may represent key mechanisms through which dietary FAs differentially impact progression of endothelial dysfunction

Heat capacity mapping mission project HCM-051

There are no author-identified significant results in this report

Pulsar timing arrays as imaging gravitational wave telescopes: angular resolution and source (de)confusion

Pulsar timing arrays (PTAs) will be sensitive to a finite number of gravitational wave (GW) "point" sources (e.g. supermassive black hole binaries). N quiet pulsars with accurately known distances d_{pulsar} can characterize up to 2N/7 distant chirping sources per frequency bin \Delta f_{gw}=1/T, and localize them with "diffraction limited" precision \delta\theta \gtrsim (1/SNR)(\lambda_{gw}/d_{pulsar}). Even if the pulsar distances are poorly known, a PTA with F frequency bins can still characterize up to (2N/7)[1-(1/2F)] sources per bin, and the quasi-singular pattern of timing residuals in the vicinity of a GW source still allows the source to be localized quasi-topologically within roughly the smallest quadrilateral of quiet pulsars that encircles it on the sky, down to a limiting resolution \delta\theta \gtrsim (1/SNR) \sqrt{\lambda_{gw}/d_{pulsar}}. PTAs may be unconfused, even at the lowest frequencies, with matched filtering always appropriate.Comment: 7 pages, 1 figure, matches Phys.Rev.D versio

Extrasolar Planets in the Classroom

The field of extrasolar planets is still, in comparison with other astrophysical topics, in its infancy. There have been about 300 or so extrasolar planets detected and their detection has been accomplished by various different techniques. Here we present a simple laboratory experiment to show how planets are detected using the transit technique. Following the simple analysis procedure describe we are able to determine the planetary radius to be 1.27 +/- 0.20 R_{J} which, within errors agrees with the establish value of 1.32 +/- 0.25 R_{J}.Comment: 7 pages, 2 figures, published in Physics Educatio

Field Measurements of Penetrator Seismic Coupling in Sediments and Volcanic Rocks

Field experiments were conducted to determine how well a seismometer installed using a penetrator would be coupled to the ground. A dry-lake bed and a lava bed were chosen as test sites to represent geological environments of two widely different material properties. At each site, two half-scale penetrators were fired into the ground, a three-component geophone assembly was mounted to the aft end of each penetrator, and dummy penetrators were at various distances to generate seismic signals. These signals were detected by the penetrator-mounted geophone assembly and by a reference geophone assembly buried or anchored to surface rock and 1-m from the penetrator. The recorded signals were digitized, and cross-spectral analyses were performed to compare the observed signals in terms of power spectral density ratio, coherence, and phase difference. The analyses indicate that seismometers deployed by penetrators will be as well coupled to the ground as are seismometers installed by conventional methods for the frequency range of interest in earthquake seismology

High-fat meals rich in EPA plus DHA compared with DHA only have differential effects on postprandial lipemia and plasma 8-isoprostane F-2 alpha concentrations relative to a control high-oleic acid meal: a randomized controlled trial

Background: Eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) supplementation has beneficial cardiovascular effects, but postprandial influences of these individual fatty acids are unclear. Objectives: The primary objective was to determine the vascular effects of EPA + DHA compared with DHA only during postprandial lipemia relative to control high–oleic acid meals; the secondary objective was to characterize the effects of linoleic acid–enriched high-fat meals relative to the control meal. Design: We conducted a randomized, controlled, double-blind crossover trial of 4 high-fat (75-g) meals containing 1) high–oleic acid sunflower oil (HOS; control), 2) HOS + fish oil (FO; 5 g EPA and DHA), 3) HOS + algal oil (AO; 5 g DHA), and 4) high–linoleic acid sunflower oil (HLS) in 16 healthy men (aged 35–70 y) with higher than optimal fasting triacylglycerol concentrations (mean ± SD triacylglycerol, 1.9 ± 0.5 mmol/L). Results: Elevations in triacylglycerol concentration relative to baseline were slightly reduced after FO and HLS compared with the HOS control (P < 0.05). The characteristic decrease from baseline in plasma nonesterified fatty acids after a mixed meal was inhibited after AO (Δ 0–3 h, P < 0.05). HLS increased the augmentation index compared with the other test meals (P < 0.05), although the digital volume pulse–reflection index was not significantly different. Plasma 8-isoprostane F(2α) analysis revealed opposing effects of FO (increased) and AO (reduced) compared with the control (P < 0.05). No differences in nitric oxide metabolites were observed. Conclusions: These data show differential postprandial 8-isoprostane F(2α) responses to high-fat meals containing EPA + DHA–rich fish oil compared with DHA-rich AO, but these differences were not associated with consistent effects on postprandial vascular function or lipemia. More detailed analyses of polyunsaturated fatty acid–derived lipid mediators are required to determine possible divergent functional effects of single meals rich in either DHA or EPA. This trial was registered at clinicaltrials.gov as NCT01618071

Remote sensing of vigor loss in conifers due to dwarf mistletoe

The initial operation of a multiband/multidate tower-tramway test site in northeastern Minnesota for the development of specifications for subsequent multiband aerial photography of more extensive study areas was completed. Multiband/multidate configurations suggested by the tower-tramway studies were and will be flown with local equipment over the Togo test site. This site was photographed by the NASA RB57F aircraft in August and September 1971. It appears that, of all the film/filter combinations attempted to date (including optical recombining of several spectral band images via photo enhancement techniques), Ektachrome infrared film with a Wratten 12 filter is the best for detecting dwarf mistletoe, and other tree diseases as well. Using this film/filter combination, infection centers are easily detectable even on the smallest photo scale (1:100,000) obtained on the Togo site

Line Broadening in Field Metal-poor Red Giant and Red Horizontal Branch Stars

We report 349 radial velocities for 45 metal-poor field red giant and red horizontal branch stars. We have have identified one new spectroscopic binary, HD 4306, and one possible such system, HD 184711. We also report 57 radial velocities for 11 of the 91 stars reported on previously by Carney et al. (2003). As was found in the previous study, radial velocity "jitter" is present in many of the most luminous stars. Excluding stars showing spectroscopic binary orbital motion, all 7 of the red giants with M(V) <= -2.0 display jitter, as well as 3 of the 14 stars with -2.0 <= M(V) <= -1.4. We have also measured line broadening in all of the new spectra, using synthetic spectra as templates. The most luminous red giants show significant line broadening, as do many of the red horizontal branch stars, and we discuss briefly possible causes.Comment: To appear in the Astronomical Journa

Transits and Occultations of an Earth-Sized Planet in an 8.5-Hour Orbit

We report the discovery of an Earth-sized planet ($1.16\pm 0.19 R_\oplus$) in an 8.5-hour orbit around a late G-type star (KIC 8435766, Kepler-78). The object was identified in a search for short-period planets in the {\it Kepler} database and confirmed to be a transiting planet (as opposed to an eclipsing stellar system) through the absence of ellipsoidal light variations or substantial radial-velocity variations. The unusually short orbital period and the relative brightness of the host star ($m_{\rm Kep}$ = 11.5) enable robust detections of the changing illumination of the visible hemisphere of the planet, as well as the occultations of the planet by the star. We interpret these signals as representing a combination of reflected and reprocessed light, with the highest planet dayside temperature in the range of 2300 K to 3100 K. Follow-up spectroscopy combined with finer sampling photometric observations will further pin down the system parameters and may even yield the mass of the planet.Comment: Accepted for publication, ApJ, 10 pages and 6 figure