7,651 research outputs found
Study of proton radiation effects on solar vehicle electronic system
Radiation effects on electronic equipment of solar spacecraft - shielding requirement
Endothelial HO-1 induction by model TG-rich lipoproteins is regulated through a NOX4-Nrf2 pathway
Circulating levels of chylomicron remnants (CMRs) increase postprandially and their composition directly reflects dietary lipid intake. These TG-rich lipoproteins likely contribute to the development of endothelial dysfunction, albeit via unknown mechanisms. Here, we investigated how the FA composition of CMRs influences their actions on human aortic endothelial cells (HAECs) by comparing the effects of model CMRs—artificial TG-rich CMR-like particles (A-CRLPs)—containing TGs extracted from fish, DHA-rich algal, corn, or palm oils. HAECs responded with distinct transcriptional programs according to A-CRLP TG content and oxidation status, with genes involved in antioxidant defense and cytoprotection most prominently affected by n-3 PUFA-containing A-CRLPs. These particles were significantly more efficacious inducers of heme oxygenase-1 (HO-1) than n-6 PUFA corn or saturated FA-rich palm CRLPs. Mechanistically, HO-1 induction by all CRLPs requires NADPH oxidase 4, with PUFA-containing particles additionally dependent upon mitochondrial reactive oxygen species. Activation of both p38 MAPK and PPARβ/δ culminates in increased nuclear factor erythroid 2-related factor 2 (Nrf2) expression/nuclear translocation and HO-1 induction. These studies define new molecular pathways coupling endothelial cell activation by model CMRs with adaptive regulation of Nrf2-dependent HO-1 expression and may represent key mechanisms through which dietary FAs differentially impact progression of endothelial dysfunction
Heat capacity mapping mission project HCM-051
There are no author-identified significant results in this report
Line Broadening in Field Metal-poor Red Giant and Red Horizontal Branch Stars
We report 349 radial velocities for 45 metal-poor field red giant and red
horizontal branch stars. We have have identified one new spectroscopic binary,
HD 4306, and one possible such system, HD 184711. We also report 57 radial
velocities for 11 of the 91 stars reported on previously by Carney et al.
(2003). As was found in the previous study, radial velocity "jitter" is present
in many of the most luminous stars. Excluding stars showing spectroscopic
binary orbital motion, all 7 of the red giants with M(V) <= -2.0 display
jitter, as well as 3 of the 14 stars with -2.0 <= M(V) <= -1.4. We have also
measured line broadening in all of the new spectra, using synthetic spectra as
templates. The most luminous red giants show significant line broadening, as do
many of the red horizontal branch stars, and we discuss briefly possible
causes.Comment: To appear in the Astronomical Journa
Remote sensing of vigor loss in conifers due to dwarf mistletoe
The initial operation of a multiband/multidate tower-tramway test site in northeastern Minnesota for the development of specifications for subsequent multiband aerial photography of more extensive study areas was completed. Multiband/multidate configurations suggested by the tower-tramway studies were and will be flown with local equipment over the Togo test site. This site was photographed by the NASA RB57F aircraft in August and September 1971. It appears that, of all the film/filter combinations attempted to date (including optical recombining of several spectral band images via photo enhancement techniques), Ektachrome infrared film with a Wratten 12 filter is the best for detecting dwarf mistletoe, and other tree diseases as well. Using this film/filter combination, infection centers are easily detectable even on the smallest photo scale (1:100,000) obtained on the Togo site
Heat Capacity Mapping Mission
The Tasman Front was delineated by airborne expendable bathythermograph survey; and an Heat Capacity Mapping Mission (HCMM) IR image on the same day shows the same principal features as determined from ground-truth. It is clear that digital enhancement of HCMM images is necessary to map ocean surface temperatures and when done, the Tasman Front and other oceanographic features can be mapped by this method, even through considerable scattered cloud cover
High-fat meals rich in EPA plus DHA compared with DHA only have differential effects on postprandial lipemia and plasma 8-isoprostane F-2 alpha concentrations relative to a control high-oleic acid meal: a randomized controlled trial
Background: Eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) supplementation has beneficial cardiovascular effects, but postprandial influences of these individual fatty acids are unclear. Objectives: The primary objective was to determine the vascular effects of EPA + DHA compared with DHA only during postprandial lipemia relative to control high–oleic acid meals; the secondary objective was to characterize the effects of linoleic acid–enriched high-fat meals relative to the control meal. Design: We conducted a randomized, controlled, double-blind crossover trial of 4 high-fat (75-g) meals containing 1) high–oleic acid sunflower oil (HOS; control), 2) HOS + fish oil (FO; 5 g EPA and DHA), 3) HOS + algal oil (AO; 5 g DHA), and 4) high–linoleic acid sunflower oil (HLS) in 16 healthy men (aged 35–70 y) with higher than optimal fasting triacylglycerol concentrations (mean ± SD triacylglycerol, 1.9 ± 0.5 mmol/L). Results: Elevations in triacylglycerol concentration relative to baseline were slightly reduced after FO and HLS compared with the HOS control (P < 0.05). The characteristic decrease from baseline in plasma nonesterified fatty acids after a mixed meal was inhibited after AO (Δ 0–3 h, P < 0.05). HLS increased the augmentation index compared with the other test meals (P < 0.05), although the digital volume pulse–reflection index was not significantly different. Plasma 8-isoprostane F(2α) analysis revealed opposing effects of FO (increased) and AO (reduced) compared with the control (P < 0.05). No differences in nitric oxide metabolites were observed. Conclusions: These data show differential postprandial 8-isoprostane F(2α) responses to high-fat meals containing EPA + DHA–rich fish oil compared with DHA-rich AO, but these differences were not associated with consistent effects on postprandial vascular function or lipemia. More detailed analyses of polyunsaturated fatty acid–derived lipid mediators are required to determine possible divergent functional effects of single meals rich in either DHA or EPA. This trial was registered at clinicaltrials.gov as NCT01618071
Technical Reference: Using Lightning Location in the Wildland Fire Assessment System
Location of the ground position of lightning discharges has been possible for several years. A technique for using ignition probability calculations together with lightning location data results in maps that are useful to fire managers in making decisions on timescales from historical to real-time. These maps, part of the Wildland Fire Assessment System, will aid fire managers in assessing the potential that lightning will result in reportable fires. The maps are generated using ignition probability based on duff depth, fuel moisture, and fuel type. To match fire potential classes, ignition probabilities are classified into ignition potential classes of low. medium, high, very high, and extreme. Possible benefits are savings in time, fire suppression costs, and perhaps even lives
Blue Dots Team Transits Working Group Review
Transiting planet systems offer an unique opportunity to observationally
constrain proposed models of the interiors (radius, composition) and
atmospheres (chemistry, dynamics) of extrasolar planets. The spectacular
successes of ground-based transit surveys (more than 60 transiting systems
known to-date) and the host of multi-wavelength, spectro-photometric follow-up
studies, carried out in particular by HST and Spitzer, have paved the way to
the next generation of transit search projects, which are currently ongoing
(CoRoT, Kepler), or planned. The possibility of detecting and characterizing
transiting Earth-sized planets in the habitable zone of their parent stars
appears tantalizingly close. In this contribution we briefly review the power
of the transit technique for characterization of extrasolar planets, summarize
the state of the art of both ground-based and space-borne transit search
programs, and illustrate how the science of planetary transits fits within the
Blue Dots perspective.Comment: 9 pages, 3 figures, to be published in the proceedings (ASP Conf.
Ser.) of the "Pathways Towards Habitable Planets" conference, held in
Barcelona (14-18 Sep 2009
A Photometric Survey for Variables and Transits in the Field of Praesepe with KELT
The Kilodegree Extremely Little Telescope (KELT) project is a small aperture,
wide-angle search for planetary transits of solar-type stars. In this paper, we
present the results of a commissioning campaign with the KELT telescope to
observe the open cluster Praesepe for 34 nights in early 2005. Lightcurves were
obtained for 69,337 stars, out of which we identify 58 long period variables
and 152 periodic variables. Sixteen of these are previously known as variable,
yielding 194 newly discovered variable stars for which we provide properties
and lightcurves. We also searched for planetary-like transits, finding four
transit candidates. Follow-up observations indicate that two of the candidates
are astrophysical false positives, with two candidates remaining as potential
planetary transits.Comment: 45 pages, 16 figures. Submitted to AJ. PDF version with full
resolution figures located at
http://www.astronomy.ohio-state.edu/~pepper/kelt.pd
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