1,500 research outputs found
Analysis of optical properties of strained semiconductor quantum dots for electromagnetically induced transparency
Using multiband k*p theory we study the size and geometry dependence on the
slow light properties of conical semiconductor quantum dots. We find the V-type
scheme for electromagnetically induced transparency (EIT) to be most favorable,
and identify an optimal height and size for efficient EIT operation. In case of
the ladder scheme, the existence of additional dipole allowed intraband
transitions along with an almost equidistant energy level spacing adds
additional decay pathways, which significantly impairs the EIT effect. We
further study the influence of strain and band mixing comparing four different
k*p band structure models. In addition to the separation of the heavy and light
holes due to the biaxial strain component, we observe a general reduction in
the transition strengths due to energy crossings in the valence bands caused by
strain and band mixing effects. We furthermore find a non-trivial quantum dot
size dependence of the dipole moments directly related to the biaxial strain
component. Due to the separation of the heavy and light holes the optical
transition strengths between the lower conduction and upper most valence-band
states computed using one-band model and eight-band model show general
qualitative agreement, with exceptions relevant for EIT operation.Comment: 9 pages, 12 figure
The interaction of 11Li with 208Pb
Background: 11Li is one of the most studied halo nuclei. The fusion of 11Li
with 208Pb has been the subject of a number of theoretical studies with widely
differing predictions, ranging over four orders of magnitude, for the fusion
excitation function.
Purpose: To measure the excitation function for the 11Li + 208Pb reaction.
Methods: A stacked foil/degrader assembly of 208Pb targets was irradiated
with a 11Li beam producing center of target beam energies from above barrier to
near barrier energies (40 to 29 MeV). The intensity of the 11Li beam (chopped)
was 1250 p/s and the beam on-target time was 34 hours. The alpha-decay of the
stopped evaporation residues was detected in a alpha-detector array at each
beam energy in the beam-off period (the beam was on for <= 5 ns and then off
for 170 ns).
Results: The 215At evaporation residues were associated with the fusion of
11Li with 208Pb. The 213,214At evaporation residues were formed by the breakup
of 11Li into 9Li + 2n, with the 9Li fusing with 208Pb. The 214At evaporation
residue appears to result from a "quasi-breakup" process.
Conclusions: Most of 11Li + 208Pb interactions lead to breakup with a small
fraction (<= 11%) leading to complete fusion.Comment: 25 pages, 11 figure
A phase I study of the safety and pharmacokinetics of the histone deacetylase inhibitor belinostat administered in combination with carboplatin and/or paclitaxel in patients with solid tumours
BACKGROUND: This phase I study assessed the maximum tolerated dose, dose-limiting toxicity (DLT) and pharmacokinetics of belinostat with carboplatin and paclitaxel and the anti-tumour activity of the combination in solid tumours. METHODS: Cohorts of three to six patients were treated with escalating doses of belinostat administered intravenously once daily, days 1-5 q21 days; on day 3, carboplatin (area under the curve (AUC) 5) and/or paclitaxel (175 mgm(-2)) were administered 2-3 h after the end of the belinostat infusion. RESULTS: In all 23 patients received 600-1000 mgm(-2) per day of belinostat with carboplatin and/or paclitaxel. No DLT was observed. The maximal administered dose of belinostat was 1000 mgm(-2) per day for days 1-5, with paclitaxel (175 mgm-2) and carboplatin AUC 5 administered on day 3. Grade III/IV adverse events were (n; %): leucopenia (5; 22%), neutropenia (7; 30%), thrombocytopenia (3; 13%) anaemia (1; 4%), peripheral sensory neuropathy (2; 9%), fatigue (1; 4%), vomiting (1; 4%) and myalgia (1; 4%). The pharmacokinetics of belinostat, paclitaxel and carboplatin were unaltered by the concurrent administration. There were two partial responses (one rectal cancer and one pancreatic cancer). A third patient (mixed mullerian tumour of ovarian origin) showed a complete CA-125 response. In addition, six patients showed a stable disease lasting >= 6 months. CONCLUSION: The combination was well tolerated, with no evidence of pharmacokinetic interaction. Further evaluation of anti-tumour activity is warranted. British Journal of Cancer (2010) 103, 12-17. doi:10.1038/sj.bjc.6605726 www.bjcancer.com Published online 15 June 2010 (C) 2010 Cancer Research U
You are the Way You Fly: On the Association between Business Travel and Business Class Travel
Italian intersociety consensus statement on antithrombotic prophylaxis in hip and knee replacement and in femoral neck fracture surgery
Anticoagulant prophylaxis for preventing venous thromboembolism (VTE) is a worldwide established procedure in hip and knee replacement surgery, as well as in the treatment of femoral neck fractures (FNF). Different guidelines are available in the literature, with quite different recommendations. None of them is a multidisciplinary effort as the one presented. The Italian Society for Studies on Haemostasis and Thrombosis (SISET), the Italian Society of Orthopaedics and Traumatology (SIOT), the association of Orthopaedists and Traumatologists of Italian Hospitals (OTODI), together with the Italian Society of Anesthesia, Analgesia, Resuscitation, and Intensive Care (SIAARTI) have set down easy and quick suggestions for VTE prophylaxis in hip and knee surgery as well as in FNF treatment. This inter-society consensus statement aims at simplifying the grading system reported in the literature, and its goal is to benefit its clinical application. Special focus is given to fragile patients, those with high bleeding risk, and those receiving chronic antiplatelet (APT) and vitamin K antagonists treatment. A special chapter is dedicated to regional anaesthesia and VTE prophylaxis
Gaseous Dark Matter Detectors
Dark Matter detectors with directional sensitivity have the potential of
yielding an unambiguous positive observation of WIMPs as well as discriminating
between galactic Dark Matter halo models. In this article, we introduce the
motivation for directional detectors, discuss the experimental techniques that
make directional detection possible, and review the status of the experimental
effort in this field.Comment: 19 pages, review on gaseous directional dark matter detectors
submitted to New Journal of Physic
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