Secondary Mathematics Teachers’ Literacy Professional Learning: An Amalgamation of Adolescent Literacy, Mathematics Teaching, and Adult Learning

This study uses practitioner research to examine secondary mathematics teachers’ learning of literacy integration practices in the context of a district-wide literacy professional development series. The author, a secondary mathematics curriculum and instruction facilitator in a large, Midwestern suburban district, engaged in a two-year partnership with seventeen Mathematics Teacher Facilitators (MTFs) who taught literacy practices to their colleagues via a train-the-trainer model. This study provides an explicit rendering of professional development practices and ongoing, job-embedded learning vignettes of six MTF’s experiences in (a) teaching literacy practices to their colleagues and (b) how they learned and enacted these practices in their classrooms. Nested in calls by the Common Core State Standards for English-Language Arts (CCSS-ELA) and Response to Intervention (RTI) process, this research is a flagship for literacy integration professional development in mathematics. The MTFs’ detailed descriptions provide valuable information regarding the discipline-specific literacy practices of secondary mathematics and offer important considerations for staff developers, curriculum coordinators, including the author, literacy/instructional coaches, and administrators seeking to improve literacy integration. Adviser: Kathleen Wilso

Acid-Base Catalysis of the Enolization of Acetone

Measurements are reported on the rate of iodination of acetone at 25°c in arsenate, phosphate, and diethylmalonic acid buffers at a constant ionic strength of 0.2. Unlike earlier results which indicate that in acetic acid buffer the expression for the reaction velocity contains an appreciable kinetic term involving the product of the concentrations of acid and anion, it has been found from the present work that such a term is experimentally immeasurable for the above mentioned buffers. This finding coupled with the relatively powerful catalysis by the phosphate and arsenate dianions could imply the simultaneous participation of these species in both an acidic and basic capacity

Misdiagnosis in Rehabilitation Settings with the Hearing Impaired Client

Non

Symptom cluster, healthcare use and mortality in patients with severe chronic obstructive pulmonary disease

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108090/1/jocn12526.pd

Pathophysiologic consequences following inhibition of a CFTR-dependent developmental cascade in the lung

BACKGROUND: Examination of late gestation developmental genes in vivo may be limited by early embryonic lethality and compensatory mechanisms. This problem is particularly apparent in evaluating the developmental role of the cystic fibrosis transmembrane conductance regulator (CFTR) gene in the cystic fibrosis (CF) phenotype. A previously described transient in utero knockout (TIUKO) technology was used to address the developmental role of CFTR in the rat lung. RESULTS: Rat fetuses transiently treated with antisense cftr in utero developed pathology that replicated aspects of the human CF phenotype. The TIUKO CF rat developed lung fibrosis, chronic inflammation, reactive airway disease, and the CF Antigen (MRP8/14), a marker for CF in human patients, was expressed. CONCLUSIONS: The transient in utero antisense technology can be used to evaluate genes that exhibit either early lethality or compensating gene phenotypes. In the lung CFTR is part of a developmental cascade for normal secretory cell differentiation. Absence of CFTR results in a constitutive inflammatory process that is involved in some aspects of CF pathophysiology

Sooner or Later... The Disappearance of Federally Subsidized Low Income Rental Housing in Minnesota.

Federal housing programs subsidized privately-owned rental housing units for low-income people since the early 1960s. The current administration in 1988, however, has reduced funding to almost zero for those programs that had provided the existing stock of affordable housing. This report documents how quickly subsidized housing is likely to be lost in Minnesota and shows what agencies and programs control which housing, how many units are involved, and where those units are located.Minnesota Housing Project

The High School in the Middle of Everywhere: Nebraska’s Lincoln High

In 2002, world-renowned author Mary Pipher published a book about her home city, Lincoln Nebraska, playfully titled “The Middle of Everywhere” a tongue-in-cheek rejoinder to the idea that Nebraska is ‘the middle of nowhere.’ But word play aside, her title was empirically apt, as her volume documented how immigration and refugee resettlement were demographically transforming Nebraska’s capital city. As in other cities, resettlement was concentrated in some areas of Lincoln, placing differential burdens on different parts of the community’s institutional infrastructure. Of interest to readers of this volume, Lincoln’s refugees and immigrants were concentrated in the city’s oldest high school. This account shares how that school embraced the challenges of demographic change by valuing the knowledge, skills and experience of students and their families

Nightingale Discourse and “Author-ity”

This essay considers current discourses circulated by what I call the Spiritual School of Nightingale production that enlarge her authority through religious authorship. Since the 1990s, this School’s distinctive populist and academic wings have been bringing out editions of her (mostly) unpublished manuscripts on religion along with their own commentaries, which construct Nightingale as a deeply spiritual author and inspirational role model by reading her writings as proofs of the “faith [. . .] central to her life, work, and thought,” rather than as textual evidences that require nonpartisan sifting. This School, which is positioned to take over Nightingale studies, can be credited with reviving interest in her work; and religious ideas could hardly have been more important for her sense of vocation. Despite the value of these efforts, especially the recently-arrived Collected Works, taking her equivocal writing about “faith” on faith of their own is problematic because it generally forecloses probing more deeply into what else these expressions might have meant or been intended to signify. What this School’s under- and over-readings miss, I argue, is the tangled “more is less” problem with the exalted terms of Nightingale’s self-authoring and the high discourses of “author-ity” that she adopted in writing on religious subjects

Long term physiologic modification using rAAV in utero gene-therapy

BACKGROUND: Transfer of genes in utero via the amniotic fluid was shown previously with recombinant adeno-associated viruses (rAAV) to be highly efficient. Expression for over one year was demonstrated using reporter genes. In addition, it was shown previously that transgenes delivered by this method release protein into the general circulation. Given these results experiments were designed to test the hypothesis that in utero rAAV gene therapy could result in long term physiologic modification. METHODS: A rAAV recombinant expressing ciliary neurotrophic factor (cntf) and green fluorescent (gfp) in a polycistronic messenger was used to treat rat fetuses in utero. CNTF causes weight loss and decreased water consumption as a measurable physiologic effect. GFP was used as a marker of gene expression. RESULTS: In utero gene transfer with rAAV carrying human cntf and gfp resulted in long-term gene expression in rat. CNTF-specific physiologic effects of a decrease in weight and water intake were obtained. Expression of the GFP was documented in the treated animals at one year of age. CONCLUSION: Given this data, in utero gene therapy with rAAV into multipotential stem cells resulted in long term systemic physiologic modification of the treated animals by the transgene product. In utero rAAV gene therapy potentially could be used for gene replacement therapy in metabolic disorders

Adult onset lung disease following transient disruption of fetal stretch-induced differentiation

One of the mechanisms by which adult disease can arise from a fetal origin is by in utero disruption of organogenesis. These studies were designed to examine respiratory function changes in aging rats following transient disruption of lung growth at 16 days gestation. Fetuses were treated in utero with a replication deficient adenovirus containing the cystic fibrosis conductance transmembrane regulator (CFTR) gene fragment cloned in the anti-sense direction. The in utero-treated rats demonstrated abnormal lung function beginning as early as 30 days of age and the pathology progressed as the animals aged. The pulmonary function abnormalities included decreased static compliance as well as increased conducting airway resistance, tissue damping, and elastance. Pressure volume (PV) curves demonstrated a slower early rise to volume and air trapping at end-expiration. The alterations of pulmonary function correlated with lung structural changes determined by morphometric analysis. These studies demonstrate how transient disruption of lung organogensis by single gene interference can result in progressive change in lung function and structure. They illustrate how an adult onset disease can arise from subtle changes in gene expression during fetal development