The patient’s skin lesions before and during antifungal treatment.

<p>A) Patient presented with skin lesions on 26th September 2013. A biopsy was taken from the large lesion and led to a diagnosis of <i>Histoplasma capsulatum</i> (see arrow). B) Clinical response after a 14-day course of amphotericin B deoxycholate (0.7 mg/kg body weight), followed by six days of fluconazole (400 mg twice daily) maintenance therapy. C) Four months into maintenance treatment, the lesions had resolved.</p

Patient characteristics.

<p>Patient characteristics.</p

Common clinical symptoms of disseminated histoplasmosis and tuberculosis.

<p>Common clinical symptoms of disseminated histoplasmosis and tuberculosis.</p

Schematic representation of the patient’s 18-month follow-up with the clinical symptoms, most important diagnostic findings, and treatment timeline.

<p>Please note that the scheme is not to scale.</p

Characteristics of the study population.

<p>Abbreviations: ALT, alanine aminotransferase; ARV, antiretroviral; HBe-Ag, Hepatitis B envelope antigen; HBsAg, Hepatitis B surface antigen; HCV, Hepatitis C virus; y, years.</p><p>Data are presented as median (interquartile range) for continuous variables and as count (column percentage) for categorical variables. P values hypothesis testing between HBsAg positive and HBsAg negative are derived from Mann-Whitney U test for continuous and χ2-test for categorical variables.</p

Test characteristics of Determine HBsAg determined in comparison with a reference test in adult and antiretroviral-naïve HIV-1 positive patients in Ifakara, Tanzania.

<p>Abbreviations: CI, confidence interval; FN, false negative; FP, false positive; NPV, negative predictive value; PPV, positive predictive value; TN, true negative; TP, true positive. Agreement is measured between two independent readings of Determine HBsAg.</p

Enrollment and outcome.

<p>Study profile of the evaluation of Determine HBsAg against a reference HBsAg enzyme immuno assay.</p