Resilient Computing Curriculum Draft -- ReSIST NoE Deliverable D16

This Deliverable presents the first version of ReSIST's Curriculum in Resilient Computing, limited to the description of the syllabi for the first year (Semesters 1 and 2) and indicates the line and title for the curriculum in the second year (semesters 3 and 4) and propose it to the general discussion for improvements. The curriculum will be updated and completed in successive versions that will take advantage of a large open discussion inside and outside ReSIS

Software Architecture and Dependability

International audienceDependable systems are characterized by a number of attributes including: reliability, availability, safety and security. For some attributes (namely for reliability, availability, safety), there exist probability- based theoretic foundations, enabling the application of dependability analysis techniques. The goal of dependability analysis is to forecast the values of dependability attributes, based on certain properties (e.g. failure rate, MTBF, etc.) that characterize the system's constituent elements. Nowadays, architects, designers and developers build systems based on an architecture-driven approach. They specify the system's software architecture using Architecture Description Languages or other standard modeling notations like UML. Given the previous, we examine what we need to specify at the architectural level to enable the automated generation of models for dependability analysis. In this paper, we further present a prototype implementation of the proposed approach, which relies on UML specifications of dependable systems' software architectures. Moreover, we exemplify our approach using a case study system

Cytokine and Chemokine Concentrations as Biomarkers of Feline Mycobacteriosis

Abstract Mycobacteriosis is an emerging zoonotic disease of domestic cats and timely, accurate diagnosis is currently challenging. To identify differential cytokine/chemokine concentrations in serum/plasma of cats, which could be diagnostic biomarkers of infection we analysed plasma/serum from 116 mycobacteria-infected cats, 16 healthy controls and six cats hospitalised for unrelated reasons was analysed using the Milliplex MAP Feline Cytokine Magnetic Bead multiplex assay. Three cytokines; sFAS, IL-13 and IL-4 were reduced while seven; GM-CSF, IL-2, PDGF-BB, IL-8, KC, RANTES and TNF-α were elevated in mycobacteria-infected cats compared to healthy controls. However, IL-8 and KC concentrations were not significantly different from cats hospitalised for other reasons. Elevations in TNF-α and PDGF-BB may have potential to identify M. bovis and M. microti infected cats specifically while GM-CSF, IL-2 and FLT3L were increased in MTBC infected cats. This study demonstrates potential use of feline tuberculosis as a spontaneously occurring model of this significant human disease. Cytokine profiling has clear diagnostic potential for mycobacteriosis of cats and could be used discriminate tuberculous from non-tuberculous disease to rapidly inform on zoonotic risk. Future work should focus on the in-field utility of these findings to establish diagnostic sensitivity and specificity of these markers

Simulating alveolar trills using a two-mass model of the tongue tip

International audienceThis paper investigates the possibility of reproducing the self-sustained oscillation of the tongue tip in alveolar trills. The interest is to study the articulatory and phonatory configurations that are required to produce alveolar trills. Using a realistic geometry of the vocal tract, derived from cineMRI data of a real speaker, the paper studies the mechanical behavior of a lumped two-mass model of the tongue tip. Then, the paper proposes a solution to simulate the incomplete occlusion of the vocal tract during linguopalatal contacts by adding a lateral acoustic waveguide. Finally, the simulation framework is used to study the impact of a set of parameters on the characteristic features of the produced alveolar trills. It shows that the production of trills is favored when the distance between the equilibrium position of the tongue tip and the hard palate in the alveolar zone is less than 1 mm, but without linguopalatal contact, and when the glottis is fully adducted