18 research outputs found
Primary use of the cutting balloon results in fewer major adverse cardiovascular events at six months than balloon angioplasty in a subgroup of patients with ostial/bifurcation or small vessel lesions
Prediction of Long-Term Incidence of Chronic Cardiovascular and Cardiopulmonary Diseases in Primary Care Patients for Population Health Monitoring: The Intermountain Chronic Disease Model (ICHRON)
THE ADDITION OF VITAMIN D TO THE INTERMOUNTAIN RISK SCORE IMPROVES THE PREDICTIVE ABILITY OF DEATH AMONG PATIENTS UNDERGOING ANGIOGRAPHY
Is atrial fibrillation an inflammatory disease reflected by elevated C-reactive protein?
Repeated Measurement of the Intermountain Risk Score Enhances Prognostication for Mortality
<div><p>Background</p><p>The Intermountain Risk Score (IMRS), composed of the complete blood count (CBC) and basic metabolic profile (BMP), predicts mortality and morbidity in medical and general populations. Whether longitudinal repeated measurement of IMRS is useful for prognostication is an important question for its clinical applicability.</p><p>Methods</p><p>Females (N = 5,698) and males (N = 5,437) with CBC and BMP panels measured 6 months to 2.0 years apart (mean 1.0 year) had baseline and follow-up IMRS computed. Survival analysis during 4.0±2.5 years (maximum 10 years) evaluated mortality (females: n = 1,255 deaths; males: n = 1,164 deaths) and incident major events (myocardial infarction, heart failure [HF], and stroke).</p><p>Results</p><p>Both baseline and follow-up IMRS (categorized as high-risk vs. low-risk) were independently associated with mortality (all p<0.001) in bivariable models. For females, follow-up IMRS had hazard ratio (HR) = 5.23 (95% confidence interval [CI] = 4.11, 6.64) and baseline IMRS had HR = 3.66 (CI = 2.94, 4.55). Among males, follow-up IMRS had HR = 4.28 (CI = 3.51, 5.22) and baseline IMRS had HR = 2.32 (CI = 1.91, 2.82). IMRS components such as RDW, measured at both time points, also predicted mortality. Baseline and follow-up IMRS strongly predicted incident HF in both genders.</p><p>Conclusions</p><p>Repeated measurement of IMRS at baseline and at about one year of follow-up were independently prognostic for mortality and incident HF among initially hospitalized patients. RDW and other CBC and BMP values were also predictive of outcomes. Further research should evaluate the utility of IMRS as a tool for clinical risk adjustment.</p></div
Association of follow-up IMRS and baseline IMRS, modeled as continuous variables, with mortality in Cox regression.
*<p>Adjusted for baseline IMRS;</p>†<p>Adjusted for follow-up IMRS. CI: confidence interval.</p