Seeing hunger through new eyes: from lack to possibility

This repository item contains a single issue of Issues in Brief, a series of policy briefs that began publishing in 2008 by the Boston University Frederick S. Pardee Center for the Study of the Longer-Range Future. This paper is part of The Project on Food and Development, a Pardee Center program of research, publications and symposia exploring the relationship between global food policy and development in its various dimensions. The project is generously supported by the Ministry of Agriculture, Nature and Food Quality of the Netherlands. The views expressed in this paper are strictly those of the author and should not be assumed to represent the views of Boston University or the Ministry of Agriculture, Nature and Food Quality of the Netherlands.This paper takes a broad and bold look at the questions of food, hunger and development, and raises questions as well as possible solutions that are often missed. This paper is part of The Project on Food and Development, a Pardee Center program of research, publications and symposia exploring the relationship between global food policy and development in its various dimensions

Measuring Food

Food system activist Anna Lappé takes stock of the pieces in this issue

A Cell Extraction Method for Oily Sediments

Hydrocarbons can be found in many different habitats and represent an important carbon source for microbes. As fossil fuels, they are also an important economical resource and through natural seepage or accidental release they can be major pollutants. DNA-specific stains and molecular probes bind to hydrocarbons, causing massive background fluorescence, thereby hampering cell enumeration. The cell extraction procedure of Kallmeyer et al. (2008) separates the cells from the sediment matrix. In principle, this technique can also be used to separate cells from oily sediments, but it was not originally optimized for this application. Here we present a modified extraction method in which the hydrocarbons are removed prior to cell extraction. Due to the reduced background fluorescence the microscopic image becomes clearer, making cell identification, and enumeration much easier. Consequently, the resulting cell counts from oily samples treated according to our new protocol are significantly higher than those treated according to Kallmeyer et al. (2008). We tested different amounts of a variety of solvents for their ability to remove hydrocarbons and found that n-hexane and – in samples containing more mature oils – methanol, delivered the best results. However, as solvents also tend to lyse cells, it was important to find the optimum solvent to sample ratio, at which hydrocarbon extraction is maximized and cell lysis minimized. A volumetric ratio of 1:2–1:5 between a formalin-fixed sediment slurry and solvent delivered highest cell counts. Extraction efficiency was around 30–50% and was checked on both oily samples spiked with known amounts of E. coli cells and oil-free samples amended with fresh and biodegraded oil. The method provided reproducible results on samples containing very different kinds of oils with regard to their degree of biodegradation. For strongly biodegraded oil MeOH turned out to be the most appropriate solvent, whereas for less biodegraded samples n-hexane delivered best results

Vegetarianism

Ethical vegetarians maintain that vegetarianism is morally required. The principal reasons offered in support of ethical vegetarianism are: (i) concern for the welfare and well-being of the animals being eaten, (ii) concern for the environment, (iii) concern over global food scarcity and the just distribution of resources, and (iv) concern for future generations. Each of these reasons is explored in turn, starting with a historical look at ethical vegetarianism and the moral status of animals

Famine

Famine, defined as excessive mortality due to extreme and protracted shortage of food, resulting from a mixture of political and economic factors, has been part of human history. Traditional thoughts of the causes of famine focused on acts of God or of nature. Later, the idea developed that famines were caused by population growth far exceeding growth in food production; however, famine still occurred in the twentieth century when there was a food surplus. The primary causes of famine in the twentieth and twenty‐first centuries can be attributed to poverty, social inequality, and failed governance

Immunostimulation and Immunoinhibition of Premalignant Lesions

BACKGROUND: The immune reaction may be either stimulatory or inhibitory to tumor growth, depending upon the local ratio of immune reactants to tumor cells. HYPOTHESIS: A tumor-stimulatory immune response may be essential for survival of a neoplasm in vivo and for the biological progression from a premalignant lesion to a malignancy. Neither a positive nor a negative correlation between the magnitude of an immune-cell infiltrate and a cancer's prognosis can reveal whether the infiltrate was stimulating or inhibiting to the tumor's growth unless the position on the nonlinear curve that relates tumor growth to the magnitude of the immune reaction is known. DISCUSSION: This hypothesis is discussed in relation to the development of human malignant melanomas and colorectal cancers

Nitric Oxide Inhibits the Rate and Strength of Cardiac Contractions in the Lobster Homarus americanus by Acting on the Cardiac Ganglion

The lobster heart is synaptically driven by the cardiac ganglion, a spontaneously bursting neural network residing within the cardiac lumen. Here, we present evidence that nitric oxide (NO) plays an inhibitory role in lobster cardiac physiology. (1) NO decreases heartbeat frequency and amplitude. Decreased frequency is a direct consequence of a decreased ganglionic burst rate. Decreased amplitude is an indirect consequence of decreased burst frequency, attributable to the highly facilitating nature of the synapses between cardiac ganglion neurons and muscle fibers (although, during prolonged exposure to NO, amplitude recovers to the original level by a frequency-independent adaptation mechanism). NO does not alter burst duration, spikes per burst, heart muscle contractility, or amplitudes of synaptic potentials evoked by stimulating postganglionic motor nerves. Thus, NO acts on the ganglion, but not on heart muscle. (2) Two observations suggest that NO is produced within the lobster heart. First, immunoblot analysis shows that nitric oxide synthase (NOS) is strongly expressed in heart muscle relative to other muscles. Second