Sequence Stratigraphy of Fine-Grained “Shale” Deposits: Case Studies of Representative Shales in the USA and China

The fine-grained “shale” deposits host a vast amount of unconventional oil and gas resources. This chapter examines the variations in lithofacies, patterns of well logs, geochemistry, and mineralogy in order to construct a sequence stratigraphic framework of the representative marine Barnett, Woodford, Marcellus, Mowry, and Niobrara fine-grained “shales” (USA) and the marine Longmaxi shale and lacustrine Chang7 lacustrine shale (China). Practical methods are proposed in order to recognize the sequence boundaries, the flooding surfaces, the parasequences and parasequence sets, the system tracts, and variation patterns of facies and rock properties. The case studies for the sequence stratigraphy in the USA and China have revealed that the transgressive systems tract (TST) and the early highstand systems tract (EHST, if identifiable) of fine-grained “shales” have been deposited in anoxic settings. TST and EHST of the siliciclastic “shales” are characterized by high gamma ray, high TOC, and high quartz content, while TST and EHST of the carbonate-dominated fine-grained “shales” are characterized by low gamma ray, organic lean, and carbonate rich fine-grained deposits. The lithofacies, geochemistry, mineralogy, depositional evolution, and reservoir development have been predicted and correlated within a sequence stratigraphic framework for the suggested cases. The best reservoir with the best completion quality is developed in TST and HST in both siliciclastic-dominated and carbonate-dominated fine-grained “shales.

What Matters: Agreement Between U.S. Courts of Appeals Judges

Federal courts are a mainstay of the justice system in the United States. In this study, we analyze 387,898 cases from U.S. Courts of Appeals, where judges are randomly assigned to panels of three. We predict which judge dissents against co-panelists and analyze the dominant features that predict such dissent with a particular attention to the biographical features that judges share. Random forest, a method developed in Breiman (2001), achieves the best classification. Dissent is predominantly driven by case features, though personal features also predict agreement

Integrative analysis and identification of key elements and pathways regulated by Traditional Chinese Medicine (Yiqi Sanjie formula) in colorectal cancer

Introduction: The clinical efficacy of Yiqi Sanjie (YQSJ) formula in the treatment of stage III colorectal cancer (CRC) has been demonstrated. However, the underlying antitumor mechanisms remain poorly understood.Materials and methods: The aim of the present study was to comprehensively characterize the molecular and microbiota changes in colon tissues and fecal samples from CRC mice and in CRC cell lines treated with YQSJ or its main active component, peiminine. Integrative tandem mass tag-based proteomics and ultra-performance liquid chromatography coupled with time-of-flight tandem mass spectrometry metabolomics were used to analyze azoxymethane/dextran sulfate sodium-induced CRC mouse colon tissues.Results: The results showed that 0.8% (57/7568) of all detected tissue proteins and 3.2% (37/1141) of all detected tissue metabolites were significantly changed by YQSJ treatment, with enrichment in ten and six pathways associated with colon proteins and metabolites, respectively. The enriched pathways were related to inflammation, sphingolipid metabolism, and cholesterol metabolism. Metabolomics analysis of fecal samples from YQSJ-treated mice identified 121 altered fecal metabolites and seven enriched pathways including protein digestion and absorption pathway. 16S rRNA sequencing analysis of fecal samples indicated that YQSJ restored the CRC mouse microbiota structure by increasing the levels of beneficial bacteria such as Ruminococcus_1 and Prevotellaceae_UCG_001. In HCT-116 cells treated with peiminine, data-independent acquisition-based proteomics analysis showed that 1073 of the 7152 identified proteins were significantly altered and involved in 33 pathways including DNA damage repair, ferroptosis, and TGF-β signaling.Conclusion: The present study identified key regulatory elements (proteins/metabolites/bacteria) and pathways involved in the antitumor mechanisms of YQSJ, suggesting new potential therapeutic targets in CRC

SocialDrought: A Social and News Media Driven Dataset and Analytical Platform towards Understanding Societal Impact of Drought

Drought poses significant challenges to sustainability across various sectors in our society, leading to substantial consequences on agriculture, environments, ecosystems, public health, and socioeconomic stability. While prior work has studied the impacts of drought using professionally measured data sources, the societal perspectives of drought impacts remain largely under-explored. In this work, we present SocialDrought, a novel and comprehensive dataset to facilitate research on the societal impacts of drought. In particular, SocialDrought consists of three major components: 1) over 1.5 million social media posts, 2) over 1,400 news articles collected and verified by domain experts, and 3) over 31,000 meteorological records from the U.S. Drought Monitor about drought severity. In addition, we also introduce an online analytical platform that enables interactive and real-time data exploration to gain timely insights into the societal impacts of drought. Our interdisciplinary dataset integrates both conventional meteorological data and unconventional social and news media data to provide a holistic understanding of drought impacts. SocialDrought opens new opportunities to study the societal impacts of drought through the lens of social and news media

Vertical deformation and tectonic activity in Tianjin area

Vertical deformation in Tianjin area during 1992–2008 was calculated from leveling data. The effect of large surface subsidence caused by extensive groundwater pumping was removed by fitting the data along each survey line with a polynomial function. The results are fitted with crustal blocks individually in this area. Vertical deformation rates are mapped, vertical rates of the main fault zones were calculated, and the activities of the blocks and fault zones were investigated. The observed vertical deformation shows that some of the blocks tilted and some blocks rose or subsided as a whole. The vertical rates at fault zones in the area vary within the range of 0.13-0.48 mm/a, with an average value of 0.29 mm/a