397 research outputs found

    Communication Skills Instruction Utilizing Interdisciplinary Peer Teachers: Program Development and Student Perceptions

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    Lack of curricular time, faculty time, and funding are potential limitations for communication skills training in dentistry. Interdisciplinary collaboration amongst health care faculties could address these limitations. This article describes the development, implementation, and student perceptions of a communication skills program in dentistry. The program has four components: Knowledge, Observation, Simulation, and Experience (KOSE) and spans over the second and third years of dental school. KOSE allows students to obtain knowledge of and observe effective communication skills and practice these skills in the simulated and nonsimulated environment. A key feature of KOSE is the utilization of fourth-year medical and dental students as peer teachers. Evaluation of KOSE was geared toward student perceptions. Cross-sectional data were gathered via written surveys from 143 learners (second- and third-year dental students) in 2006–07. Students perceived the ability to recognize effective communication, demonstrated awareness of their communication strengths and weaknesses, and reported that skills gained were transferable to actual patient care. Interdisciplinary collaboration was a feasible way to address the lack of resources in the development of a communications skills program, which was perceived to be worthwhile by learners

    Observation of Porosity Reduction in a Densification-Prone Test Fuel Rod: Data and Analysis

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    Instrumented fuel assembly (IFA)-431 was irradiated in the Halden Boiling Water Reactor (HBWR) for the purpose of extending the steady-state data base. Rod 6 of this assembly began irradiation with UO{sub 2} fuel of 92% theoretical density (TD) that was unstable with respect to in-reactor densification. Thermal resintering tests resulted in a final density of 95.3% TD while post-irradiation examination (PIE) indicated a final density of 96.5% TD. Observed microstructural changes were consistent with published densification studies; there was a marked depletion of submicrometer diameter pores and total pore volume. However, grain size increased only slightly, indicating that internal pellet temperatures did not reach the 1875K applied in resintering tests. Oensification was observed to increase the temperatures in rod 6, but temperatures did not become as high as for a sibling rod that simulated instantaneous densification. Temperatures calculated with U.S. Nuclear Regulatory Commission (NRC) fuel performance computer codes were generally higher than observed temperatures

    Immunolocalization of KATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature.

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    BACKGROUND: Electrophysiological data suggest that cardiac KATP channels consist of Kir6.2 and SUR2A subunits, but the distribution of these (and other KATP channel subunits) is poorly defined. We examined the localization of each of the KATP channel subunits in the mouse and rat heart. RESULTS: Immunohistochemistry of cardiac cryosections demonstrate Kir6.1 protein to be expressed in ventricular myocytes, as well as in the smooth muscle and endothelial cells of coronary resistance vessels. Endothelial capillaries also stained positive for Kir6.1 protein. Kir6.2 protein expression was found predominantly in ventricular myocytes and also in endothelial cells, but not in smooth muscle cells. SUR1 subunits are strongly expressed at the sarcolemmal surface of ventricular myocytes (but not in the coronary vasculature), whereas SUR2 protein was found to be localized predominantly in cardiac myocytes and coronary vessels (mostly in smaller vessels). Immunocytochemistry of isolated ventricular myocytes shows co-localization of Kir6.2 and SUR2 proteins in a striated sarcomeric pattern, suggesting t-tubular expression of these proteins. Both Kir6.1 and SUR1 subunits were found to express strongly at the sarcolemma. The role(s) of these subunits in cardiomyocytes remain to be defined and may require a reassessment of the molecular nature of ventricular KATP channels. CONCLUSIONS: Collectively, our data demonstrate unique cellular and subcellular KATP channel subunit expression patterns in the heart. These results suggest distinct roles for KATP channel subunits in diverse cardiac structures

    Design innovation for the 1990's

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    Statement of responsibility on title-page reads: Richard K. Lester, Michael J. Driscoll, Michael W. Golay, David D. Lanning, Lawrence M. Lidsky, Norman C. Rasmussen and Neil E. Todreas"September 1983."Includes bibliographical reference

    An intermediate-depth source of hydrothermal 3He and dissolved iron in the North Pacific

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    We observed large water column anomalies in helium isotopes and trace metal concentrations above the Loihi Seamount. The 3He/4He of the added helium was 27.3 times the atmospheric ratio, clearly marking its origin to a primitive mantle plume. The dissolved iron to 3He ratio (dFe:3He) exported to surrounding waters was 9.3 ± 0.3 × 106. We observed the Loihi 3He and dFe “signal” at a depth of 1100 m at several stations within ∼100 – 1000 km of Loihi, which exhibited a distal dFe:3He ratio of ∼4 × 106, about half the proximal ratio. These ratios were remarkably similar to those observed over and near the Southern East Pacific Rise (SEPR) despite greatly contrasting geochemical and volcanictectonic origins. In contrast, the proximal and distal dMn:3He ratios were both ∼ 1 × 106, less than half of that observed at the SEPR. Dissolved methane was minimally enriched in waters above Loihi Seamount and was distally absent. Using an idealized regional-scale model we replicated the historically observed regional 3He distribution, requiring a hydrothermal 3He source from Loihi of 10.4 ± 4.2 mola−1, ∼2% of the global abyssal hydrothermal 3He flux. From this we compute a corresponding dFe flux of ∼40 Mmola−1. Global circulation model simulations suggest that the Loihi-influenced waters eventually upwell along the west coast of North America, also extending into the shallow northwest Pacific, making it a possibly important determinant of marine primary production in the subpolar North Pacific

    Precharacterization Report for Instrumented Fuel Assembly (IFA)-527

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    This report is a resource document covering the rationale, design, fabrication, and preirradiation characterization of instrumented fuel assembly (IFA)-527. This assembly is being irradiated in the Halden Boiling Water Reactor (HBWR) in Norway as part of the Experimental Support and Development of Single-Rod Fuel Codes Program conducted by Pacific Northwest laboratory (PNL) and sponsored by the Fuel Behavior Research Branch of the U.S. Nuclear Regulatory Commission (NRC). Data from this assembly will be used to better understand light water reactor (LWR) fuel behavior under normal operating conditions

    Scattered-Light Echoes from the Historical Galactic Supernovae Cassiopeia A and Tycho (SN 1572)

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    We report the discovery of an extensive system of scattered light echo arclets associated with the recent supernovae in the local neighbourhood of the Milky Way: Tycho (SN 1572) and Cassiopeia A. Existing work suggests that the Tycho SN was a thermonuclear explosion while the Cas A supernova was a core collapse explosion. Precise classifications according to modern nomenclature require spectra of the outburst light. In the case of ancient SNe, this can only be done with spectroscopy of their light echo, where the discovery of the light echoes from the outburst light is the first step. Adjacent light echo positions suggest that Cas A and Tycho may share common scattering dust structures. If so, it is possible to measure precise distances between historical Galactic supernovae. On-going surveys that alert on the development of bright scattered-light echo features have the potential to reveal detailed spectroscopic information for many recent Galactic supernovae, both directly visible and obscured by dust in the Galactic plane.Comment: 4 pages, 4 color figures, accepted for publication in ApJ

    Isolation of a wide range of minerals from a thermally treated plant: Equisetum arvense, a Mare’s tale

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    Silica is the second most abundant biomineral being exceeded in nature only by biogenic CaCO3. Many land plants (such as rice, cereals, cucumber, etc.) deposit silica in significant amounts to reinforce their tissues and as a systematic response to pathogen attack. One of the most ancient species of living vascular plants, Equisetum arvense is also able to take up and accumulate silica in all parts of the plant. Numerous methods have been developed for elimination of the organic material and/or metal ions present in plant material to isolate biogenic silica. However, depending on the chemical and/or physical treatment applied to branch or stem from Equisetum arvense; other mineral forms such glass-type materials (i.e. CaSiO3), salts (i.e. KCl) or luminescent materials can also be isolated from the plant material. In the current contribution, we show the chemical and/or thermal routes that lead to the formation of a number of different mineral types in addition to biogenic silica
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