Sulfate-reducing bacteria in human periodontitis

Contains fulltext : 19014_sulfbainh.pdf (publisher's version ) (Open Access)Periodontitis is the major cause of the loss of teeth among adults. A mixture of bacteria then settles under the gingiva, and is implicated in the degradation of tooth-supporting tissue. In the deepening lesion, or pocket, the adjacent bone is degraded too, which will eventually lead to the loss of the tooth. Professor van der Hoeven has shown 6 years ago in Nijmegen, The Netherlands, that a new group of bacteria occurs in periodontal pockets: Sulfate-reducing bacteria (SRB). The sulfide produced by these bacteria does not only smell like rotten egg, but it is very toxic. The thesis of Dr. P.S. Langendijk showed that SRB from the mouth differ from species that occur in sediments, activated sludge or intestines of humans and animals. She describes SRB from periodontitis patients as a new species: Desulfomicrobium orale. And with DNA-techniques she demonstrated also the presence of other species, which have not been described yet. Furthermore, she found that SRB occur in about 10% of healthy subjects in the mouth, mostly at the tongue and in plaque. But these bacteria occur significantly more often in periodontitis, the SRB grow in circa 70% of the patients in pockets. The occurrence of SRB was increased with bleeding and in deeper pockets, which showed their relationship with severity of periodontitis. Debridement of a pocket by the periodontist and oral hygienist was in many cases (95%) effective against SRB and this resulted in increased tissue attachment. Sulfate-reducing bacteria could be used as a risk-indicator for the treatment of periodontitis.125 p

Quantitative fluorescence in situ hybridization of Bifidobacterium spp. with genus-specific 16S rRNA-targeted probes and its application in fecal samples.

Contains fulltext : 20973___.PDF (publisher's version ) (Open Access

Quantitative fluorescence in situ hybridization of Bifidobacterium spp. with genus-specific 16S rRNA-targeted probes and its application in fecal samples.

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Sulfate-reducing bacteria in association with human periodontitis

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Decrease of sulfate-reducing bacteria after initial periodontal disease

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Sulfate-reducing bacteria in relation with other potential periodontal pathogens

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Isolation of Desulfomicrobium orale sp. Nov. and Desulfovibrio strain NY682, oral sulfate-reducing bacteria involved in human periodontal disease

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Archaeal -CASP Ribonucleases of the aCPSF1 Family are Orthologs of the Eukaryal CPSF-73 factor

International audienc

Archaeal β-CASP ribonucleases of the aCPSF1 family are orthologs of the eukaryal CPSF-73 factor.

International audienc