Building a Paragraph Using Sources for Support

This handout has examples of three different examples of how to use sources for supporting an argument in a paragraph

Writing a Professional Email

This handout provides guidelines to help students construct a professional email by listing dos and don\u27ts of formatting and outlining components

Building a Paragraph Using Sources for Support

This handout shows how to construct a paragraph using sources for support and includes a sample paragraph

Building a Paragraph Using Sources for Support (Handout)

This handout shows how to construct a paragraph using sources for support and includes a sample paragraph

Writing a Professional Email

This handout provides guidelines to help students construct a professional email by listing dos and don\u27ts of formatting and outlining components

Prospectus, December 5, 2019

‘TIS THE SEASON TO ACE FINALS; Parkland Theatre gets into the spirit with A Christmas Carol; Happy holidays, joyeuses fêtes, felices vacaciones; College Student Wishlist: Student Discounts; Letter to the Editor: Thank You Parkland!; Meet the staff: Sidney Mounts; Holiday Movies: Traditions, praises & critiques; The history of the holiday seasonhttps://spark.parkland.edu/prospectus_2019/1051/thumbnail.jp

The Grizzly, November 30, 2006

Alcohol Awareness on the Front Burner of the Ursinus Campus • Diversity Forum Held for Staff and Students • 2nd Annual Relay for Life Officially Kicked Off at Ursinus • Town Hall Discusses Incidents on Campus • An Oral Examination • UCDC Performs Superbly in Latest Show • People Seeing People: The Artwork of Seward Johnson • Highlights of the Exposure Week Events and Festivities • Opinions: The Meaning of Liberal Arts; Racism in Our World and Home • Ursinus 2006 Division III Field Hockey National Champions! • Swimming to Successhttps://digitalcommons.ursinus.edu/grizzlynews/1726/thumbnail.jp

A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models

Breast cancer research is hampered by difficulties in obtaining and studying primary human breast tissue, and by the lack of in vivo preclinical models that reflect patient tumor biology accurately. To overcome these limitations, we propagated a cohort of human breast tumors grown in the epithelium-free mammary fat pad of SCID/Beige and NOD/SCID/IL2γ-receptor null (NSG) mice, under a series of transplant conditions. Both models yielded stably transplantable xenografts at comparably high rates (~21% and ~19%, respectively). Of the conditions tested, xenograft take rate was highest in the presence of a low-dose estradiol pellet. Overall, 32 stably transplantable xenograft lines were established, representing 25 unique patients. Most tumors yielding xenografts were “triple-negative” (ER-PR-HER2+) (n=19). However, we established lines from three ER-PR-HER2+ tumors, one ER+PR-HER2−, one ER+PR+HER2− and one “triple-positive” (ER+PR+HER2+) tumor. Serially passaged xenografts show biological consistency with the tumor of origin, are phenotypically stable across multiple transplant generations at the histologic, transcriptomic, proteomic, and genomic levels, and show comparable treatment responses as those observed clinically. Xenografts representing 12 patients, including two ER+ lines, showed metastasis to the mouse lung. These models thus serve as a renewable, quality-controlled tissue resource for preclinical studies investigating treatment response and metastasis

EUFOREA/EPOS2020 statement on the clinical considerations for CRSwNP care

Following the European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA) treatment algorithm for chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP), patients suffering from severe uncontrolled CRSwNP are recommended to receive oral corticosteroids, (revision) sinus surgery, systemic biologicals and/or aspirin treatment after desensitization (ATAD). Given the major differences in indications, outcomes, practical considerations, risks and costs of these key pillars of treatment, there is a growing need to define criteria for each treatment option and list the clinically relevant and major considerations for them. This EUFOREA document therefore provides an expert panel overview of the expected outcomes, specific considerations and (contra)indications of the five major treatment arms of severe uncontrolled CRSwNP: oral corticosteroids, primary and revision sinus surgery, biological treatment and ATAD. This overview of treatment considerations is needed to allow physicians and patients to consider the different options in the context of providing optimal and personalized care for severe uncontrolled CRSwNP. In conclusion, the five major treatment options for severe uncontrolled CRSwNP have intrinsic advantages, specific indications and considerations that are of importance to the patient, the physician and the society. This EUFOREA statement supports the unmet need to define criteria for the indication of every treatment pillar of CRSwNP