4,781 research outputs found
Wireless recording of the calls of Rousettus aegyptiacus and their reproduction using electrostatic transducers
Bats are capable of imaging their surroundings in great detail using echolocation. To apply similar methods to human engineering systems requires the capability to measure and recreate the signals used, and to understand the processing applied to returning echoes. In this work, the emitted and reflected echolocation signals of Rousettus aegyptiacus are recorded while the bat is in flight, using a wireless sensor mounted on the bat. The sensor is designed to replicate the acoustic gain control which bats are known to use, applying a gain to returning echoes that is dependent on the incurred time delay. Employing this technique allows emitted and reflected echolocation calls, which have a wide dynamic range, to be recorded. The recorded echoes demonstrate the complexity of environment reconstruction using echolocation. The sensor is also used to make accurate recordings of the emitted calls, and these calls are recreated in the laboratory using custom-built wideband electrostatic transducers, allied with a spectral equalization technique. This technique is further demonstrated by recreating multi-harmonic bioinspired FM chirps. The ability to record and accurately synthesize echolocation calls enables the exploitation of biological signals in human engineering systems for sonar, materials characterization and imaging
PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications
Protein kinase R (PKR) has previously been suggested to mediate many of the deleterious consequences of a high-fat diet (HFD). However, previous studies have observed substantial phenotypic variability when examining the metabolic consequences of PKR deletion. Accordingly, herein, we have re-examined the role of PKR in the development of obesity and its associated metabolic complications in vivo as well as its putative lipid-sensing role in vitro. Here we show that the deletion of PKR does not affect HFD-induced obesity, hepatic steatosis or glucose metabolism, and only modestly affects adipose tissue inflammation. Treatment with the saturated fatty acid palmitate in vitro induced comparable levels of inflammation in WT and PKR KO macrophages, demonstrating that PKR is not necessary for the sensing of pro-inflammatory lipids. These results challenge the proposed role for PKR in obesity, its associated metabolic complications and its role in lipid-induced inflammation
Why does the Engel method work? Food demand, economies of size and household survey methods
Estimates of household size economies are needed for the analysis of poverty and inequality. This paper shows that Engel estimates of size economies are large when household expenditures are obtained by respondent recall but small when expenditures are obtained by daily recording in diaries. Expenditure estimates from recall surveys appear to have measurement errors correlated with household size. As well as demonstrating the fragility of Engel estimates of size economies, these results help resolve a puzzle raised by Deaton and Paxson (1998) about differences between rich and poor countries in the effect of household size on food demand
Temperature evolution and bifurcations of metastable states in mean-field spin glasses, with connections with structural glasses
The correlations of the free-energy landscape of mean-field spin glasses at
different temperatures are investigated, concentrating on models with a first
order freezing transition. Using a ``potential function'' we follow the
metastable states of the model in temperature, and discuss the possibility of
level crossing (which we do not find) and multifurcation (which we find). The
dynamics at a given temperature starting from an equilibrium configuration at a
different temperature is also discussed. In presence of multifurcation, we find
that the equilibrium is never achieved, leading to aging behaviour at slower
energy levels than usual aging. The relevance of the observed mechanisms for
real structural glasses is discussed, and some numerical simulations of a soft
sphere model of glass are presented.Comment: 16 pages, LaTeX, 10 figures (12 postscript files
Minimal Model for Sand Dunes
We propose a minimal model for aeolian sand dunes. It combines an analytical
description of the turbulent wind velocity field above the dune with a
continuum saltation model that allows for saturation transients in the sand
flux. The model provides a qualitative understanding of important features of
real dunes, such as their longitudinal shape and aspect ratio, the formation of
a slip face, the breaking of scale invariance, and the existence of a minimum
dune size.Comment: 4 pages, 4 figures, replaced with publishd versio
Path integrals on a flux cone
This paper considers the Schroedinger propagator on a cone with the conical
singularity carrying magnetic flux (``flux cone''). Starting from the operator
formalism and then combining techniques of path integration in polar
coordinates and in spaces with constraints, the propagator and its path
integral representation are derived. "Quantum correction" in the Lagrangian
appears naturally and no a priori assumption is made about connectivity of the
configuration space.Comment: LaTeX file, 9 page
An introduction to phase transitions in stochastic dynamical systems
We give an introduction to phase transitions in the steady states of systems
that evolve stochastically with equilibrium and nonequilibrium dynamics, the
latter defined as those that do not possess a time-reversal symmetry. We try as
much as possible to discuss both cases within the same conceptual framework,
focussing on dynamically attractive `peaks' in state space. A quantitative
characterisation of these peaks leads to expressions for the partition function
and free energy that extend from equilibrium steady states to their
nonequilibrium counterparts. We show that for certain classes of nonequilibrium
systems that have been exactly solved, these expressions provide precise
predictions of their macroscopic phase behaviour.Comment: Pedagogical talk contributed to the "Ageing and the Glass Transition"
Summer School, Luxembourg, September 2005. 12 pages, 8 figures, uses the IOP
'jpconf' document clas
Outer-Sphere Contributions to the Electronic Structure of Type Zero Copper Proteins
Bioinorganic canon states that active-site
thiolate coordination promotes rapid electron transfer (ET)
to and from type 1 copper proteins. In recent work, we have
found that copper ET sites in proteins also can be constructed
without thiolate ligation (called “type zero” sites). Here we
report multifrequency electron paramagnetic resonance
(EPR), magnetic circular dichroism (MCD), and nuclear
magnetic resonance (NMR) spectroscopic data together with
density functional theory (DFT) and spectroscopy-oriented
configuration interaction (SORCI) calculations for type zero Pseudomonas aeruginosa azurin variants. Wild-type (type 1) and type
zero copper centers experience virtually identical ligand fields. Moreover, O-donor covalency is enhanced in type zero centers
relative that in the C112D (type 2) protein. At the same time, N-donor covalency is reduced in a similar fashion to type 1
centers. QM/MM and SORCI calculations show that the electronic structures of type zero and type 2 are intimately linked to the
orientation and coordination mode of the carboxylate ligand, which in turn is influenced by outer-sphere hydrogen bonding
Holographic Reconstruction and Renormalization in Asymptotically Ricci-flat Spacetimes
In this work we elaborate on an extension of the AdS/CFT framework to a
subclass of gravitational theories with vanishing cosmological constant. By
building on earlier ideas, we construct a correspondence between Ricci-flat
spacetimes admitting asymptotically hyperbolic hypersurfaces and a family of
conformal field theories on a codimension two manifold at null infinity. By
truncating the gravity theory to the pure gravitational sector, we find the
most general spacetime asymptotics, renormalize the gravitational action,
reproduce the holographic stress tensors and Ward identities of the family of
CFTs and show how the asymptotics is mapped to and reconstructed from conformal
field theory data. In even dimensions, the holographic Weyl anomalies identify
the bulk time coordinate with the spectrum of central charges with
characteristic length the bulk Planck length. Consistency with locality in the
bulk time direction requires a notion of locality in this spectrum.Comment: 44 pages, 4 figures. v2: minor changes in section
The prescribed mean curvature equation in weakly regular domains
We show that the characterization of existence and uniqueness up to vertical
translations of solutions to the prescribed mean curvature equation, originally
proved by Giusti in the smooth case, holds true for domains satisfying very
mild regularity assumptions. Our results apply in particular to the
non-parametric solutions of the capillary problem for perfectly wetting fluids
in zero gravity. Among the essential tools used in the proofs, we mention a
\textit{generalized Gauss-Green theorem} based on the construction of the weak
normal trace of a vector field with bounded divergence, in the spirit of
classical results due to Anzellotti, and a \textit{weak Young's law} for
-minimizers of the perimeter.Comment: 23 pages, 1 figure --- The results on the weak normal trace of vector
fields have been now extended and moved in a self-contained paper available
at: arXiv:1708.0139
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