760 research outputs found

    Justification in the Old Testament

    Get PDF
    This topic needs discussion not only because of the value of such study, but also because of the large amount of opposition to the Old Testament at the present time and the immense forces that are directing their efforts to overthrow the Old Testament. On the one hand we have those opponents who because of anti-Semitic fanaticism want to reject the Old Testament from the outset, while on the other hand we meet those who wish to oppose the Old Testament by their own conjectures and thus overthrow it. The latter, negative Bible critics, try to find in the books of the Old Testament something which isn\u27t there, but which they place there they try to find a development of doctrine

    Synthesis of 2-Chloro-3-phthalimido-4-azetidinone and Related Derivatives from Penicillins

    Get PDF
    The current interest in new azetidinone antibiotics and their preparation has stimulated an intensive search for the synthesis of appropriately substituted monocyclic azetidinones.2- 5 Our initial efforts in this field resulted in the chlorinolysis of the carbon-sulfur bond in penicillin

    Reactions of Penicillin Esters and Related Compounds with 1-Chlorobenzotriazole

    Get PDF
    Recently we reported chlorinolysis of the carbon-sulfur bond in penicillins1. Depending on the amount of halogen used, two kinds of products are .isolated. With 1 mole of chlorine, the reaction gives azetidinone sulfenyl chlorides III and with 2 moles of chlorine, olefinic azetidinone derivatives IV are formed

    Thiazabicycloheptenones. Synthesis of Bicyclic Thiazoline Azetidinone Derivatives

    Get PDF
    Chlorinolysis of the S1-C5 bond in penicillin G and the subsequent cyclization of the obtained product to the thiazabicycloheptenone is described. The intermediate azetidinone imidoyl chloride III is prepared by treatment of the olefinic azetidinone II with phosphorous pentachloride. Cyclization of III is effected with thioacetate anion or hydrogen sulfide in the presence .of triethylamine. The structure and chirality of thiazabicycloheptenone IV were established by spectral data as well as by comparison with the sample prepared by an independent manner3 from penicillin G sulfoxide

    Synthesis of 2-Chloro-3-phthalimido-4-azetidinone and Related Derivatives from Penicillins

    Get PDF
    The current interest in new azetidinone antibiotics and their preparation has stimulated an intensive search for the synthesis of appropriately substituted monocyclic azetidinones.2- 5 Our initial efforts in this field resulted in the chlorinolysis of the carbon-sulfur bond in penicillin

    Reactions of Penicillin Esters and Related Compounds with 1-Chlorobenzotriazole

    Get PDF
    Recently we reported chlorinolysis of the carbon-sulfur bond in penicillins1. Depending on the amount of halogen used, two kinds of products are .isolated. With 1 mole of chlorine, the reaction gives azetidinone sulfenyl chlorides III and with 2 moles of chlorine, olefinic azetidinone derivatives IV are formed

    Topological Phases in Graphitic Cones

    Full text link
    The electronic structure of graphitic cones exhibits distinctive topological features associated with the apical disclinations. Aharonov-Bohm magnetoconductance oscillations (period Phi_0) are completely absent in rings fabricated from cones with a single pentagonal disclination. Close to the apex, the local density of states changes qualitatively, either developing a cusp which drops to zero at the Fermi energy, or forming a region of nonzero density across the Fermi energy, a local metalization of graphene.Comment: 4 pages, RevTeX 4, 3 PostScript figure

    A continuous isotropic-nematic liquid crystalline transition of F-actin solutions

    Full text link
    The phase transition from the isotropic (I) to nematic (N) liquid crystalline suspension of F-actin of average length 3Ā Ī¼3~\mum or above was studied by local measurements of optical birefringence and protein concentration. Both parameters were detected to be continuous in the transition region, suggesting that the I-N transition is higher than 1st order. This finding is consistent with a recent theory by Lammert, Rokhsar & Toner (PRL, 1993, 70:1650), predicting that the I-N transition may become continuous due to suppression of disclinations. Indeed, few line defects occur in the aligned phase of F-actin. Individual filaments in solutions of a few mg/ml F-actin undergo fast translational diffusion along the filament axis, whereas both lateral and rotational diffusions are suppressed.Comment: 4 pages with 4 figures. Submitted to Physical Review Letter
    • ā€¦
    corecore