Human Centered Design Stages & Research Methods.

<p>Human Centered Design Stages & Research Methods.</p

Accuracy and actionability.

<p>Accuracy and actionability.</p

Tailored, educational, & promotional message content.

<p>Tailored, educational, & promotional message content.</p

Message content ratings.

<p>Message content ratings.</p

Image1_Asthma, Airflow Obstruction, and Eosinophilic Airway Inflammation Prevalence in Western Kenya: A Population-Based Cross-Sectional Study.JPEG

Objectives: Determine the prevalence of airway disease (e.g., asthma, airflow obstruction, and eosinophilic airway inflammation) in Kenya, as well as related correlates of airway disease and health-related quality of life.Methods: A three-stage, cluster-randomized cross-sectional study in Uasin Gishu County, Kenya was conducted. Individuals 12 years and older completed questionnaires (including St. George’s Respiratory Questionnaire for COPD, SGRQ-C), spirometry, and fractional exhaled nitric oxide (FeNO) testing. Prevalence ratios with 95% confidence intervals (CIs) were calculated. Multivariable models were used to assess correlates of airflow obstruction and high FeNO.Results: Three hundred ninety-two participants completed questionnaires, 369 completed FeNO testing, and 305 completed spirometry. Mean age was 37.5 years; 64% were women. The prevalence of asthma, airflow obstruction on spirometry, and eosinophilic airway inflammation was 21.7%, 12.3% and 15.7% respectively in the population. Women had significantly higher SGRQ-C scores compared to men (15.0 vs. 7.7). Wheezing or whistling in the last year and SGRQ-C scores were strongly associated with FeNO levels >50 ppb after adjusting for age, gender, BMI, and tobacco use.Conclusion: Airway disease is a significant health problem in Kenya affecting a young population who lack a significant tobacco use history.</p

DataSheet1_Asthma, Airflow Obstruction, and Eosinophilic Airway Inflammation Prevalence in Western Kenya: A Population-Based Cross-Sectional Study.docx

Objectives: Determine the prevalence of airway disease (e.g., asthma, airflow obstruction, and eosinophilic airway inflammation) in Kenya, as well as related correlates of airway disease and health-related quality of life.Methods: A three-stage, cluster-randomized cross-sectional study in Uasin Gishu County, Kenya was conducted. Individuals 12 years and older completed questionnaires (including St. George’s Respiratory Questionnaire for COPD, SGRQ-C), spirometry, and fractional exhaled nitric oxide (FeNO) testing. Prevalence ratios with 95% confidence intervals (CIs) were calculated. Multivariable models were used to assess correlates of airflow obstruction and high FeNO.Results: Three hundred ninety-two participants completed questionnaires, 369 completed FeNO testing, and 305 completed spirometry. Mean age was 37.5 years; 64% were women. The prevalence of asthma, airflow obstruction on spirometry, and eosinophilic airway inflammation was 21.7%, 12.3% and 15.7% respectively in the population. Women had significantly higher SGRQ-C scores compared to men (15.0 vs. 7.7). Wheezing or whistling in the last year and SGRQ-C scores were strongly associated with FeNO levels >50 ppb after adjusting for age, gender, BMI, and tobacco use.Conclusion: Airway disease is a significant health problem in Kenya affecting a young population who lack a significant tobacco use history.</p

Temporal trends of the average CD4 count at ART initiation.

<p>Reference line shows the 350 cells/mm³ CD4 count threshold.</p

Temporal trends of patients starting ART with advanced HIV disease (WHO stage 3/4).

<p>Temporal trends of patients starting ART with advanced HIV disease (WHO stage 3/4).</p

Among women in care after 6 months on ART, cumulative incidence of attrition of pregnant women at ART initiation compared with non-pregnant women, with and without advanced disease.

<p>Among women in care after 6 months on ART, cumulative incidence of attrition of pregnant women at ART initiation compared with non-pregnant women, with and without advanced disease.</p

Characteristics of participants at ART initiation.

<p>Characteristics of participants at ART initiation.</p