Is the critical Shields stress for incipient sediment motion dependent on channel-bed slope?

Data from laboratory flumes and natural streams show that the critical Shields stress for initial sediment motion increases with channel slope, which indicates that particles of the same size are more stable on steeper slopes. This observation is contrary to standard models that predict reduced stability with increasing slope due to the added downstream gravitational force. Processes that might explain this discrepancy are explored using a simple force-balance model, including increased drag from channel walls and bed morphology, variable friction angles, grain emergence, flow aeration, and changes to the local flow velocity and turbulent fluctuations. Surprisingly, increased drag due to changes in bed morphology does not appear to be the cause of the slope dependency because both the magnitude and trend of the critical Shields stress are similar for flume experiments and natural streams, and significant variations in bed morphology in flumes is unlikely. Instead, grain emergence and changes in local flow velocity and turbulent fluctuations seem to be responsible for the slope dependency due to the coincident increase in the ratio of bed-roughness scale to flow depth (i.e., relative roughness). A model for the local velocity within the grain-roughness layer is proposed based on a 1-D eddy viscosity with wake mixing. In addition, the magnitude of near-bed turbulent fluctuations is shown to depend on the depth-averaged flow velocity and the relative roughness. Extension of the model to mixed grain sizes indicates that the coarser fraction becomes increasingly difficult to transport on steeper slopes

Gamma-Ray Bursts as a Probe of the Very High Redshift Universe

We show that, if many GRBs are indeed produced by the collapse of massive stars, GRBs and their afterglows provide a powerful probe of the very high redshift (z > 5) universe.Comment: To appear in Proc. of the 5th Huntsville Gamma-Ray Burst Symposium, 5 pages, LaTe

Treatment compliance and effectiveness of a cognitive behavioural intervention for low back pain : a complier average causal effect approach to the BeST data set

Background: Group cognitive behavioural intervention (CBI) is effective in reducing low-back pain and disability in comparison to advice in primary care. The aim of this analysis was to investigate the impact of compliance on estimates of treatment effect and to identify factors associated with compliance. Methods: In this multicentre trial, 701 adults with troublesome sub-acute or chronic low-back pain were recruited from 56 general practices. Participants were randomised to advice (control n = 233) or advice plus CBI (n = 468). Compliance was specified a priori as attending a minimum of three group sessions and the individual assessment. We estimated the complier average causal effect (CACE) of treatment. Results: Comparison of the CACE estimate of the mean treatment difference to the intention-to-treat (ITT) estimate at 12 months showed a greater benefit of CBI amongst participants compliant with treatment on the Roland Morris Questionnaire (CACE: 1.6 points, 95% CI 0.51 to 2.74; ITT: 1.3 points, 95% CI 0.55 to 2.07), the Modified Von Korff disability score (CACE: 12.1 points, 95% CI 6.07 to 18.17; ITT: 8.6 points, 95% CI 4.58 to 12.64) and the Modified von Korff pain score (CACE: 10.4 points, 95% CI 4.64 to 16.10; ITT: 7.0 points, 95% CI 3.26 to 10.74). People who were non-compliant were younger and had higher pain scores at randomisation. Conclusions: Treatment compliance is important in the effectiveness of group CBI. Younger people and those with more pain are at greater risk of non-compliance

Poincare' normal forms and simple compact Lie groups

We classify the possible behaviour of Poincar\'e-Dulac normal forms for dynamical systems in $R^n$ with nonvanishing linear part and which are equivariant under (the fundamental representation of) all the simple compact Lie algebras and thus the corresponding simple compact Lie groups. The ``renormalized forms'' (in the sense of previous work by the author) of these systems is also discussed; in this way we are able to simplify the classification and moreover to analyze systems with zero linear part. We also briefly discuss the convergence of the normalizing transformations.Comment: 17 pages; minor corrections in revised versio

Massive particles in acoustic space-times emergent inertia and passive gravity

I show that massive-particle dynamics can be simulated by a weak, spherical, external perturbation on a potential flow in an ideal fluid. The effective Lagrangian is of the form mc^2L(U^2/c^2), where U is the velocity of the particle relative to the fluid and c the speed of sound. This can serve as a model for emergent relativistic inertia a la Mach's principle with m playing the role of inertial mass, and also of analog gravity where it is also the passive gravitational mass. m depends on the particle type and intrinsic structure, while L is universal: For D dimensional particles L is proportional to the hypergeometric function F(1,1/2;D/2;U^2/c^2). Particles fall in the same way in the analog gravitational field independent of their internal structure, thus satisfying the weak equivalence principle. For D less or equal 5 they all have a relativistic limit with the acquired energy and momentum diverging as U approaches c. For D less or equal 7 the null geodesics of the standard acoustic metric solve our equation of motion. Interestingly, for D=4 the dynamics is very nearly Lorentzian. The particles can be said to follow the geodesics of a generalized acoustic metric of a Finslerian type that shares the null geodesics with the standard acoustic metric. In vortex geometries, the ergosphere is automatically the static limit. As in the real world, in ``black hole'' geometries circular orbits do not exist below a certain radius that occurs outside the horizon. There is a natural definition of antiparticles; and I describe a mock particle vacuum in whose context one can discuss, e.g., particle Hawking radiation near event horizons.Comment: 15 page: version published in Physical Review

Draft genome sequences of gammaproteobacterial methanotrophs isolated from lake washington sediment.

The genomes of Methylosarcina lacus LW14(T) (=ATCC BAA-1047(T) = JCM 13284(T)), Methylobacter sp. strain 21/22, Methylobacter sp. strain 31/32, Methylomonas sp. strain LW13, Methylomonas sp. strain MK1, and Methylomonas sp. strain 11b were sequenced and are reported here. All the strains are obligately methanotrophic bacteria isolated from the sediment of Lake Washington

On the motion of a heavy rigid body in an ideal fluid with circulation

Chaplygin's equations describing the planar motion of a rigid body in an unbounded volume of an ideal fluid involved in a circular flow around the body are considered. Hamiltonian structures, new integrable cases, and partial solutions are revealed, and their stability is examined. The problems of non-integrability of the equations of motion because of a chaotic behavior of the system are discussed.Comment: 25 pages, 4 figure

A frictionless microswimmer

We investigate the self-locomotion of an elongated microswimmer by virtue of the unidirectional tangential surface treadmilling. We show that the propulsion could be almost frictionless, as the microswimmer is propelled forward with the speed of the backward surface motion, i.e. it moves throughout an almost quiescent fluid. We investigate this swimming technique using the special spheroidal coordinates and also find an explicit closed-form optimal solution for a two-dimensional treadmiler via complex-variable techniques.Comment: 6 pages, 4 figure

A Conserved Functional Domain of Drosophila Coracle Is Required for Localization at the Septate Junction and Has Membrane-organizing Activity

This is the published version, also available here: http://dx.doi.org/10.1083/jcb.140.6.1463.The protein 4.1 superfamily is comprised of a diverse group of cytoplasmic proteins, many of which have been shown to associate with the plasma membrane via binding to specific transmembrane proteins. Coracle, a Drosophila protein 4.1 homologue, is required during embryogenesis and is localized to the cytoplasmic face of the septate junction in epithelial cells. Using in vitro mutagenesis, we demonstrate that the amino-terminal 383 amino acids of Coracle define a functional domain that is both necessary and sufficient for proper septate junction localization in transgenic embryos. Genetic mutations within this domain disrupt the subcellular localization of Coracle and severely affect its genetic function, indicating that correct subcellular localization is essential for Coracle function. Furthermore, the localization of Coracle and the transmembrane protein Neurexin to the septate junction display an interdependent relationship, suggesting that Coracle and Neurexin interact with one another at the cytoplasmic face of the septate junction. Consistent with this notion, immunoprecipitation and in vitro binding studies demonstrate that the amino-terminal 383 amino acids of Coracle and cytoplasmic domain of Neurexin interact directly. Together these results indicate that Coracle provides essential membrane-organizing functions at the septate junction, and that these functions are carried out by an amino-terminal domain that is conserved in all protein 4.1 superfamily members

From attosecond to zeptosecond coherent control of free-electron wave functions using semi-infinite light fields

Light-electron interaction in empty space is the seminal ingredient for free-electron lasers and also for controlling electron beams to dynamically investigate materials and molecules. Pushing the coherent control of free electrons by light to unexplored timescales, below the attosecond, would enable unprecedented applications in light-assisted electron quantum circuits and diagnostics at extremely small timescales, such as those governing intramolecular electronic motion and nuclear phenomena. We experimentally demonstrate attosecond coherent manipulation of the electron wave function in a transmission electron microscope, and show that it can be pushed down to the zeptosecond regime with existing technology. We make a relativistic pulsed electron beam interact in free space with an appropriately synthesized semi-infinite light field generated by two femtosecond laser pulses reflected at the surface of a mirror and delayed by fractions of the optical cycle. The amplitude and phase of the resulting coherent oscillations of the electron states in energymomentum space are mapped via momentum-resolved ultrafast electron energy-loss spectroscopy. The experimental results are in full agreement with our theoretical framework for light-electron interaction, which predicts access to the zeptosecond timescale by combining semi-infinite X-ray fields with free electrons.Comment: 22 pages, 6 figure