Brownian ratchets driven by asymmetric nucleation of hydrolysis waves

We propose a stochastic process wherein molecular transport is mediated by asymmetric nucleation of domains on a one-dimensional substrate. Track-driven mechanisms of molecular transport arise in biophysical applications such as Holliday junction positioning and collagenase processivity. In contrast to molecular motors that hydrolyze nucleotide triphosphates and undergo a local molecular conformational change, we show that asymmetric nucleation of hydrolysis waves on a track can also result in directed motion of an attached particle. Asymmetrically cooperative kinetics between ``hydrolyzed'' and ``unhydrolyzed'' states on each lattice site generate moving domain walls that push a particle sitting on the track. We use a novel fluctuating-frame, finite-segment mean field theory to accurately compute steady-state velocities of the driven particle and to discover parameter regimes which yield maximal domain wall flux, leading to optimal particle drift.Comment: 5 pp, 6 fig

Thermodynamic Properties of Partially Miscible Systems: Part II- Binary Systems of Cyclohexane with Acetic Anhydride & Furfural

231-23

Thermodynamic Properties of Solutions of Monochloro, Dichloro- & Trichloroacetic Acids in Water

639-64

Traumatic Dental Injuries Among 12-15-Year-Old-School Children in Panchkula

Background:: Traumatic dental injury (TDI) in children and adolescents has become one of the most serious dental public health problems. Despite such a high prevalence of dental trauma, very less attention has been paid to TDI, its etiology, and prevention. Objectives:: To determine the prevalence of anterior tooth traumatic dental injuries in 12-15-year-old school children of Panchkula district, India, and to find any correlation with the cause, gender, extent of overbite as well as over-jet, and previous treatment. Patients and Methods:: A multistage sample of 12-15-year-old school children (n = 810) in Panchkula district, Haryana, was selected. The children were screened using WHO criteria for oral examination and a trained dental surgeon examined the children. Those with clinical TDI were examined further for the type of traumatic injuries using Elis classification modified by Holland. Overjet and overbite were recorded. After examination, questions regarding the cause of trauma and its treatment were asked. Data were subjected to statistical analysis using the Chi square and Mantel-Haenszel tests by SPSS version 20.0. Results:: The results showed that out of 810 children, 86 (10.2 %) had TDI. Males had higher prevalence of trauma than females (P < 0.05). The common cause of trauma was fall (51.11%) followed by sports injuries (41.86%). Enamel-dentin fracture without pulpal involvement was the most common type of trauma and the most frequent involved teeth were maxillary central incisors. A significant association was observed between overjet and overbite and trauma. Only 3.5% of the children affected with trauma had received treatment. Conclusions:: The prevalence of traumatic injuries to permanent incisors in 12-15-year-old Panchkula school children was relatively high. TDI was associated with gender, overjet, and lip competence. There was a great unmet treatment need

Phase Transitions in Adsorbates: Part III - Vapour Pressure Studies on Formic Acid, tert-Butyl Alcohol & Cyclohexane Adsorbed on Charcoal

649-65

Phase Transition in Adsorbates: Part VIII-Anomalous Phase Transition Behaviour of Adsorbed Dioxane & Benzene

101-10

Phase Transitions in Adsorbates: Part IV - Behaviour of Acetic Acid Dioxane & p-Xylene Adsorbed on Silica Gel

276-27

Thermochemical Studies of Partially Miscible Liquid Pairs of Furfural with n-Hexane & n- Heptane

174-17

Enthalpies of Mixing of Polyoxyethylene Glycols in Benzene, Carbon Tetrachloride, Methyl Alcohol & Ethyl Alcohol

642-64

Thermochemical Studies on Ternary Systems: Part I-Enthalpies of Mixing of Polyoxyethylene Glycols in Aqueous Dioxane & Ethyl Alcohol

645-64