62 research outputs found
Drivers of Change or Cut-Throat Competitors? Challenging Cultures of Innovation of Chinese and Nigerian Migrant Entrepreneurs in West Africa
L'afflux remarquable des entrepreneurs migrants chinois dans différents pays d'Afrique occidentale au cours des dernières années a été heurtée à une résistance de plus en plus farouche par des entrepreneurs locaux établis. Que le premiers ont un avantage concurrentiel sur ce dernier en raison de traits socio-culturels distinctifs, ou si l'efficacité supposée chinoise est juste une caractéristique de toutes les diasporas mercantiles, est ouvert à la question. Cette étude exploratoire des migrants entrepreneuriales chinois et nigérians au Ghana et au Bénin tente de répondre à cette question. Apparemment, les forces culturels des agents du changement migrants ne sont pas limités à des systèmes de valeurs héritées ou religions, comme une éthique protestante ou le confucianisme, mais ils sont adaptés en permanence et ont inventé de nouveau par des réseaux transnationaux de la migration dans un monde globalisé. Il n'y a aucune preuve d'une prétendue supériorité de la culture d’innovation chinois par rapport aux cultures d’innovation africains des migrants entrepreneuriales. Plutôt, il existe une capacité accrue d'innovation d'une diaspora mercantile en général vis à vis des entrepreneurs locaux, indépendamment de l'origine de la culture nationale dans lequel il est intégré. En outre, la rivalité des entrepreneurs migrants chinois et nigérians dans les marchés africains ne conduit pas nécessairement à la concurrence coupe-gorge souvent suspectée sous l'impact de la mondialisation. Souvent, les deux groupes agissent plutôt complémentaires. Cela contribue, sous certaines conditions, même à la réduction de la pauvreté dans le pays d'accueil
Le sens de l'effort (approche neuropsychologique)
Nous présentons 4 études de neuropsychologie expérimentale réalisées dans le but de mieux comprendre la nature et les bases neurales de la perception de la force musculaire (PFM). Les performances de patients (patiente déafférentée, patients atteints de schizophrénie ou des maladies de Huntington et de Parkinson) à des tâches de PFM ont été analysées. Il ressort que l'intensité d'une contraction musculaire (CM) volontaire est perçue indirectement, par le biais de l'effort qui a permis de l'engendrer. Notre proposition est de subdiviser la sensation d'effort en deux composantes: l'intention d'effort (IE), lorsque le système fonctionne sans information en provenance de la CM; la sensation d'effort musculaire (SEM), lorsque les informations centrales et périphériques codant pour la force interagissent. L'IE pourrait prendre sa source dans l'aire motrice supplémentaire. Les ganglions de la base semblent participer au processus d'actualisation de la représentation corticale de l'effort, c'est-à -dire à la SEMLYON1-BU.Sciences (692662101) / SudocSudocFranceF
Un atlas du potentiel neuroplastique chez les patients cérébrolésés
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The dorsal cingulate cortex as a critical gateway in the network supporting conscious awareness
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Production and perception of grip force without proprioception: is there a sense of effort in deafferented subjects?
International audienceWe assessed the ability of healthy subjects (n = 7) and a patient deprived of proprioception (GL) to produce and assess different levels of isometric forces. They first produced a target force with one hand (the reference control hand) and then, after a delay of 3 s, they attempted to match it with the other hand (the experimental matching hand). Despite abnormal variations in motor outputs, we found that GL could, as could the control subjects, maintain a constant relationship between the force exerted by the control hand and the force exerted by the experimental hand. As GL was deprived of proprioceptive cues, these results suggest that she indirectly perceived muscular force through central effort. Interestingly, when carrying out the task the patient reported neither feelings of fatigue nor awareness of how hard she tried to perform the matches. Hence, under certain circumstances (such as in our motor task), it seems possible to assess and scale muscular force on the basis of endogenous signals only. However, internally generated signals related to the size of the motor command may need to interact with afferent input to gain full access to consciousness
Damage to the left uncinate fasciculus is associated with heightened schizotypal traits: A multimodal lesion-mapping study
A growing body of evidence suggests that individuals with pronounced schizotypal traits also display particular neurophysiological and morphological features – notably with regard to left frontotemporal connectivity. However, the studies published to date have focused on subclinical subjects and psychiatric patients, rather than brain-damaged patients. Here, we used the French version of the Schizotypal Personality Questionnaire to assess schizotypal traits in a sample of 97 patients having undergone surgical resection of a diffuse low-grade glioma. Patients having received other neurooncological treatments (including chemotherapy and radiotherapy) were not included. A combination of ROI-based based voxel-wise and tract-wise lesion-symptom mapping and a disconnectome analysis were performed, in order to identify the putative neural network associated with schizotypy. The ROI-based lesion-symptom mapping revealed a significant relationship between the cognitive-perceptual (positive) dimension of schizotypy and the left inferior gyrus (including the pars opercularis and the pars orbitalis). Importantly, we found that disconnection of the left uncinate fasciculus (UF) was a powerful predictor of the positive dimension of schizotypy. Lastly, the disconnection analysis indicated that the positive dimension of schizotypy was significantly associated with the white matter fibres deep in the left orbital and inferior frontal gyri and the left superior temporal pole, which mainly correspond to the spatial topography of the left UF. Taken as a whole, our results suggest that dysconnectivity of the neural network supplied by the left UF is associated with heightened positive schizotypal traits. Our new findings may be of value in interpreting current research in the field of biological psychiatry
Preserved metacognitive ability despite unilateral or bilateral anterior prefrontal resection
Personality and behavioral changes after brain tumor resection: a lesion mapping study
International audienceBackground: Cognitive functioning is generally well preserved in patients with diffuse low-grade glioma (DLGG), even in the case of extended tumor and resection. To date, the question of personality changes in these patients has received little attention. Our aim was to investigate to what extent certain aspects of personality and behaviors could be affected by DLGG resection.Methods: We used self-reported personality questionnaires (NOEPI-R and TCI-R) and hetero-evaluation of executive behavioral changes in a large sample of 98 patients operated on for DLGG. To compare the patients' scores from the personality questionnaires, we recruited 47 healthy controls participants. To identify the putative neural networks associated with behavioral changes, a combination of voxel-wise and tract-wise lesion-symptom mapping was performed.Results: First, results revealed no difference between patients and controls for each subdimension of the NOEPI-R. Regarding the TCI-R, the character dimensions and three out of four temperament dimensions did not differ. Second, behavioral changes (Irritability, Hypoactivity, Anticipative disorders, and disinterest) were reported between 40 and 50% of cases. Third, some personality dimensions (as neuroticism) were strongly predictive of postoperative behavioral disorders (as hypoactivity). Lastly, specific behavioral changes were associated with selective damage to cortical (left inferior frontal gyrus, supplementary motor area, and right fusiform gyrus) and white matter (left inferior fronto-occipital and uncinate fasciculi, right cingulum) structures.Conclusion: This study demonstrates that extensive lesions caused by DLGGs and their surgical resection have no or minor impact on patients' personality. However, specific personality dimensions are strongly predictive of behavioral disorders suggesting that the observed surgically related behavioral changes are modulated by the personality profile. Finally, the lesion mapping analyses indicate that damage to differential cortical or white matter structures leads to distinct patterns of behavioral abnormalities
The ability to assess muscular force in asymmetrical Parkinson's disease.
International audienceWe tested the ability of eight Parkinson's disease (PD) patients with clearly asymmetrical right-sided motor signs and eight control subjects to assess different levels of muscular forces. In Experiment 1, subjects had first to produce a target-force with one hand (the reference hand) with the assistance of visual feedback, and then match that force with the other hand (the matching hand) without any visual feedback. In Experiment 2, they had to produce a target-force with one hand and then estimate it by attributing a numerical value. In Experiment 1, the results showed that PD patients could normally reach the target-forces with the more affected left hand but they were impaired in inter-manual force transfer. They were also impaired, in Experiment 2, in estimating forces produced by their more affected hand. Our findings suggest that PD patients present a deficit in sensing motor effort. Effort awareness might be mediated by the basal ganglia
Mapping neuroplastic potential in brain-damaged patients
International audienceIt is increasingly acknowledged that the brain is highly plastic. However, the anatomic factors governing the potential for neuroplasticity have hardly been investigated. To bridge this knowledge gap, we generated a probabilistic atlas of functional plasticity derived from both anatomic magnetic resonance imaging results and intraoperative mapping data on 231 patients having undergone surgery for diffuse, low-grade glioma. The atlas includes detailed level of confidence information and is supplemented with a series of comprehensive, connectivity-based cluster analyses. Our results show that cortical plasticity is generally high in the cortex (except in primary unimodal areas and in a small set of neural hubs) and rather low in connective tracts (especially associative and projection tracts). The atlas sheds new light on the topological organization of critical neural systems and may also be useful in predicting the likelihood of recovery (as a function of lesion topology) in various neuropathological conditions-a crucial factor in improving the care of brain-damaged patients
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