1,886 research outputs found
Current situation analysis of the government invested project management
2004-2005 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
Analysis on the critical factors of over-time and over-pay problems for government engineering project construction
2007-2008 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
Construction and demolition waste management in Hong Kong
Author name used in this publication: J Jian-li HaoAuthor name used in this publication: C N L Fan2005-2006 > Academic research: refereed > Chapter in an edited book (author)Version of RecordPublishe
Promoting urbanization towards sustainable development
2000-2001 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
Analyzing and modeling the construction-drive of China
2000-2001 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
A generic decision model for developing concentrated rural settlement in post-disaster reconstruction : a China study
2013-2014 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe
Risks in Chinese construction market
2003-2004 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
Mathematical analysis of SOFC based on co-ionic conducting electrolyte
2012-2013 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe
Investigation on why the practice of rural residence land exchange is different under development driven condition and disaster induced condition
Version of RecordPublishe
Dynamic Transcription of Distinct Classes of Endogenous Retroviral Elements Marks Specific Populations of Early Human Embryonic Cells
SummaryAbout half of the human genome consists of highly repetitive elements, most of which are considered dispensable for human life. Here, we report that repetitive elements originating from endogenous retroviruses (ERVs) are systematically transcribed during human early embryogenesis in a stage-specific manner. Our analysis highlights that the long terminal repeats (LTRs) of ERVs provide the template for stage-specific transcription initiation, thereby generating hundreds of co-expressed, ERV-derived RNAs. Conversion of human embryonic stem cells (hESCs) to an epiblast-like state activates blastocyst-specific ERV elements, indicating that their activity dynamically reacts to changes in regulatory networks. In addition to initiating stage-specific transcription, many ERV families contain preserved splice sites that join the ERV segment with non-ERV exons in their genomic vicinity. In summary, we find that ERV expression is a hallmark of cellular identity and cell potency that characterizes the cell populations in early human embryos
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