9 research outputs found
Drug susceptibility profiles of pulmonary Mycobacterium tuberculosis isolates from patients in informal urban settlements in Nairobi, Kenya
Full text linkAlienusolin, a New 4 alpha-Deoxyphorbol Ester Derivative, and Crotonimide C, a New Glutarimide Alkaloid from the Kenyan Croton alienus
No full textAlienusolin, a New 4 alpha-Deoxyphorbol Ester Derivative, and Crotonimide C, a New Glutarimide Alkaloid from the Kenyan Croton alienus
No full text
New ent-clerodane and abietane diterpenoids from the roots of Kenyan Croton megalocarpoides
Get PDFThe roots of the endangered medicinal plant Croton megalocarpoides (Euphorbiaceae) collected in Kenya has been investigated. Twenty two compounds has been isolated. Among them twelve new ¬ent-clerodane (1-12) and a new abietane (13) diterpenoid alongside the known crotocorylifuran (4a), two known abietane and four known ent-trachylobane diterpenoids, and the triterpenoids, lupeol and acetyl aleurotolic acid. The structures of the compounds were determined using NMR, HRMS and ECD. The isolated compounds have been evaluated against a series of microorganisms (fungal and bacteria) and also against Plasmodium falciparum, however no activity was observed
New ent-clerodane and abietane diterpenoids from the roots of Kenyan Croton megalocarpoides
No full textThe roots of the endangered medicinal plant Croton megalocarpoides (Euphorbiaceae) collected in Kenya has been investigated. Twenty two compounds has been isolated. Among them twelve new ¬ent-clerodane (1-12) and a new abietane (13) diterpenoid alongside the known crotocorylifuran (4a), two known abietane and four known ent-trachylobane diterpenoids, and the triterpenoids, lupeol and acetyl aleurotolic acid. The structures of the compounds were determined using NMR, HRMS and ECD. The isolated compounds have been evaluated against a series of microorganisms (fungal and bacteria) and also against Plasmodium falciparum, however no activity was observed
