The Possibility of Promoting User Participation in Working with High-Risk Youth

Advocacy for promoting user participation in the helping process of social work has been reported in the literature since the 1970s, but the practicality of the concept for different clienteles of social work has been rarely explored. This paper presents a recent qualitative study on exploring the applicability of user participation in work with high-risk youth in the streets who are usually regarded as immature and low in both self-confidence and the ability to make the 'right' decisions. The findings of the study support the promotion of the concept of user participation in working with high-risk youth. Positive changes and growth were observed among this group with the application of user participation in the helping process. Ways for promoting the implementation of this concept in work with high-risk youth are suggested.postprin

FIB patterning of stainless steel for the development of nano-structured stent surfaces for cardiovascular applications

Stent implantation is a percutaneous interventional procedure that mitigates vessel stenosis, providing mechanical support within the artery and as such a very valuable tool in the fight against coronary artery disease. However, stenting causes physical damage to the arterial wall. It is well accepted that a valuable route to reduce in-stent re-stenosis can be based on promoting cell response to nano-structured stainless steel (SS) surfaces such as by patterning nano-pits in SS. In this regard patterning by focused ion beam (FIB) milling offers several advantages for flexible prototyping. On the other hand FIB patterning of polycrystalline metals is greatly influenced by channelling effects and redeposition. Correlative microscopy methods present an opportunity to study such effects comprehensively and derive structure–property understanding that is important for developing improved patterning. In this chapter we present a FIB patterning protocol for nano-structuring features (concaves) ordered in rectangular arrays on pre-polished 316L stainless steel surfaces. An investigation based on correlative microscopy approach of the size, shape and depth of the developed arrays in relation to the crystal orientation of the underlying SS domains is presented. The correlative microscopy protocol is based on cross-correlation of top-view scanning electron microscopy, electron backscattering diffraction, atomic force microscopy and cross-sectional (serial) sectioning. Various FIB tests were performed, aiming at improved productivity by preserving nano-size accuracy of the patterned process. The optimal FIB patterning conditions for achieving reasonably high throughput (patterned rate of about 0.03 mm2/h) and nano-size accuracy in dimensions and shapes of the features are discussed as well

Mono-PEGylated thermostable Bacillus caldovelox arginase mutant (BCA‑M‑PEG20) induces apoptosis, autophagy, cell cycle arrest and growth inhibition in gastric cancer cells

202309 bcvcVersion of RecordRGCOthersState Key Laboratory of Chemical Biology and Drug Discovery; PolyU Postdoc Matching Fund Scheme; Lo Ka Chung Charitable Foundation Limited; Hong Kong Polytechnic UniversityPublishe

Changes in heart-rate variability of survivors of nasopharyngeal cancer during Tai Chi Qigong practice

[Purpose] To explore the changes in heart-rate variability (HRV) of survivors of nasopharyngeal cancer (NPC) before, during, and after a Tai Chi (TC) Qigong exercise. [Subjects and Methods] Eleven survivors of NPC participated voluntarily in the study. The heart rate of each participant was measured continuously for 1 minute before the TC Qigong intervention, during the 5-minute TC Qigong intervention, and for 1 minute after the intervention, using a Polar heart-rate monitor. Spectral HRV was expressed in terms of normalised low frequency (LF) power, normalised high frequency (HF) power, and the low frequency/high frequency (LF/HF) power ratio. [Results] Both the LF-power and the HF-power components had significant time effects. However, the time effect of the LF/HF power ratio was not significant. Post hoc contrast analysis revealed a significant decrease in LF power and a concomitant increase in HF power during the 4th minute and 5th minute of the TC Qigong exercise. [Conclusion] Five minutes of TC Qigong exercise was found to improve HRV by increasing HF power and decreasing LF power, but these effects were transient. TC Qigong might be an appropriate exercise for improving the ANS function and psychological and cardiac health of survivors of NPC

Lysine deprivation suppresses adipogenesis in 3T3-L1 cells : a transcriptome analysis

202307 bcchVersion of RecordOthersRAP startup fund; Hong Kong Polytechnic UniversityPublishe

Racial and Socioeconomic Disparities in Body Mass Index among College Students: Understanding the Role of Early Life Adversity

The role of early life adversity (ELA) in the development of health disparities has not received adequate attention. The current study examined differential exposure and differential vulnerability to ELA as explanations for socioeconomic and racial disparities in body mass index (BMI). Data were derived from a sample of 150 college students (Mage = 18.8, SD = 1.0; 45 % African American; 55 % European American) who reported on parents’ education and income as well as on exposure to 21 early adverse experiences. Body measurements were directly assessed to determine BMI. In adjusted models, African American students had higher BMI than European Americans. Similarly, background socioeconomic status was inversely associated with BMI. Significant mediation of group disparities through the pathway of ELA was detected, attenuating disparities by approximately 40 %. Furthermore, ELA was more strongly associated with BMI for African Americans than for European Americans. Efforts to achieve health equity may need to more fully consider early adversity