14 research outputs found
A reappraisal of the natural and experimental host range of Neotropical Phytophthora capsici isolates from Solanaceae, Cucurbitaceae, Rosaceae, and Fabaceae
Fungal Planet description sheets: 107-127
AgriwetenskappeBewaringsekologie en EntomologiePlease help us populate SUNScholar with the post print version of this article. It can be e-mailed to: [email protected]
Control of Phytophthora melonis damping-off treated with 24-epibrassinolide and a histological study of cucumber hypocotyl
Analysis of microsatellites from transcriptome sequences of Phytophthora capsici and applications for population studies
Inheritance of resistance in chilli against root and collar rot caused by Phytophthora capsici
Analysis of genetic diversity in Phytophthora colocasiae causing leaf blight of taro (Colocasia esculenta) using AFLP and RAPD markers
Negative regulators of plant immunity derived from cinnamyl alcohol dehydrogenases are targeted by multiple Phytophthora Avr3aâlike effectors
Oomycete pathogens secrete numerous effectors to manipulate host immunity. While some effectors share a conserved structural fold, it remains unclear if any have conserved host targets. Avr3aâlike family effectors, which are related to Phytophthora infestans effector PiAvr3a and are widely distributed across diverse clades of Phytophthora species, were used to study this question.
By using yeastâtwoâhybrid, bimolecular fluorescence complementation and coâimmunoprecipitation assays, we identified members of the plant cinnamyl alcohol dehydrogenase 7 (CAD7) subfamily as targets of multiple Avr3aâlike effectors from Phytophthora pathogens.
The CAD7 subfamily has expanded in plant genomes but lost the lignin biosynthetic activity of canonical CAD subfamilies. In turn, we identified CAD7s as negative regulators of plant immunity that are induced by Phytophthora infection. Moreover, AtCAD7 was stabilized by Avr3aâlike effectors and involved in suppression of pathogenâassociated molecular patternâtriggered immunity, including callose deposition, reactive oxygen species burst and WRKY33 expression.
Our results reveal CAD7 subfamily proteins as negative regulators of plant immunity that are exploited by multiple Avr3aâlike effectors to promote infection in different host plants