Teleportation of an arbitrary multipartite state via photonic Faraday rotation

We propose a practical scheme for deterministically teleporting an arbitrary multipartite state, either product or entangled, using Faraday rotation of the photonic polarization. Our scheme, based on the input-output process of single-photon pulses regarding cavities, works in low-Q cavities and only involves virtual excitation of the atoms, which is insensitive to both cavity decay and atomic spontaneous emission. Besides, the Bell-state measurement is accomplished by the Faraday rotation plus product-state measurements, which could much relax the experimental difficulty to realize the Bell-state measurement by the CNOT operation.Comment: 11 pages, 2 figures

The Anchoring Effect of “Quality Threshold for Monetary Incentive” on Online Review Platforms

The “quality threshold for monetary incentive” mechanism is a common practice in online review platforms. However, the effect of the quality threshold is still not clear in the extant literature. This study attempts to investigate how the introduction of the quality threshold affects content quality. Based on the Anchoring Effect theory, this study first derives some theoretical conclusions based on theoretical models and then conducts a natural experiment to test the conclusions. The findings show that after introducing the quality threshold, (1) the proportion of content with the threshold-level quality will increase; (2) the proportion of content higher than the quality threshold is reduced when there is the “Anchoring Effect”. Moreover, the empirical study also shows that the quality threshold leads to an overall negative effect on the average review quality. Our findings are meaningful to the stakeholders of the online review platforms

Investigation of a Side-polished Fiber MZI and Its Sensing Performance

A novel all-fiber Mach–Zehnder interferometer (MZI), which consists of lateral core fusion splicing of a short section of side-polished single mode fiber (SMF) between two SMFs was proposed and demonstrated. A simple fiber side-polished platform was built to control the side polished depth through a microscope. The sensitivity of the fiber MZI structure to the surrounding refractive index (RI) can be greatly improved with the increase of the side-polished depth, but has no effect on the temperature sensitivity. The sensor with a polished depth of 44.2 μm measured RI sensitivity up to -118.0 nm/RIU (RI unit) in the RI range from 1.333 to 1.387, which agrees well with simulation results by using the beam propagation method (BPM). In addition, the fiber MZI structure also can achieve simultaneous measurement of both RI and temperature. These results show its potential for use in-line fiber type sensing application

A Novel Aptamer LL4A Specifically Targets Vemurafenib-Resistant Melanoma through Binding to the CD63 Protein.

Melanoma is a highly aggressive tumor with a poor prognosis, and half of all melanoma patients harbor BRAF mutations. A BRAF inhibitor, vemurafenib (PLX4032), has been approved by the US Food and Drug Administration (FDA) and European Medicines Agency (EMA) to treat advanced melanoma patients with BRAFV600E mutation. However, the efficacy of vemurafenib is impeded by adaptive resistance in almost all patients. In this study, using a cell-based SELEX (systematic evolution of ligands by exponential enrichment) strategy, we obtained a DNA aptamer (named LL4) with high affinity and specificity against vemurafenib-resistant melanoma cells. Optimized truncated form (LL4A) specifically binds to vemurafenib-resistant melanoma cells with dissociation constants in the nanomolar range and with excellent stability and low toxicity. Meanwhile, fluorescence imaging confirmed that LL4A significantly accumulated in tumors formed by vemurafenib-resistant melanoma cells, but not in control tumors formed by their corresponding parental cells in vivo. Further, a transmembrane protein CD63 was identified as the binding target of aptamer LL4A using a pull-down assay combined with the liquid chromatography-tandem mass spectrometry (LC-MS/MS) method. CD63 formed a supramolecular complex with TIMP1 and β1-integrin, activated the nuclear factor кB (NF-кB) and mitogen-activated protein kinase (MAPK) signaling pathways, and contributed to vemurafenib resistance. Potentially, the aptamer LL4A may be used diagnostically and therapeutically in humans to treat targeted vemurafenib-resistant melanoma

Bis{μ-4′-[4-(quinolin-8-yloxymeth­yl)phen­yl]-2,2′:6′,2′′-terpyridine}disilver(I) bis­(perchlorate) dimethyl­formamide disolvate

In the binuclear title complex, [Ag2(C31H22N4O)2](ClO4)2·2C3H7NO, the AgI atom is penta­coordinated by three N atoms from the tridentate chelating terpyridyl group and by one N atom and one O atom from the quinolin-8-yl­oxy group in a distorted square-pyramidal geometry with the O atom at the apical position. The centrosymmetric complex cation involves intra­molecular π–π stacking inter­actions [centroid–centroid distance = 3.862 (4) Å] between the central pyridine and benzene rings. In the crystal structure, inter­molecular C—H⋯O hydrogen bonds result in the formation of a supra­molecular network