Spin Polarisability of the Nucleon in the Heavy Baryon Effective Field Theory

We have constructed a heavy baryon effective field theory with photon as an external field in accordance with the symmetry requirements similar to the heavy quark effective field theory. By treating the heavy baryon and anti-baryon equally on the same footing in the effective field theory, we have calculated the spin polarisabilities $\gamma_i, i=1...4$ of the nucleon at third order and at fourth-order of the spin-dependent Compton scattering. At leading order (LO), our results agree with the corresponding results of the heavy baryon chiral perturbation theory, at the next-to-leading order(NLO) the results show a large correction to the ones in the heavy baryon chiral perturbation theory due to baryon-antibaryon coupling terms. The low energy theorem is satisfied both at LO and at NLO. The contributions arising from the heavy baryon-antibaryon vertex were found to be significant and the results of the polarisabilities obtained from our theory is much closer to the experimental data.Comment: 21pages, title changed, minimal correction

On Dust Extinction of Gamma-ray Burst Host Galaxies

Although it is well recognized that gamma-ray burst (GRB) afterglows are obscured and reddened by dust in their host galaxies, the wavelength-dependence and quantity of dust extinction are still poorly known. Current studies on this mostly rely on fitting the afterglow spectral energy distributions (SEDs) with template extinction models. The inferred extinction (both quantity and wavelength-dependence) and dust-to-gas ratios are often in disagreement with that obtained from dust depletion and X-ray spectroscopy studies. We argue that this discrepancy could result from the prior assumption of a template extinction law. We propose an analytical formula to approximate the GRB host extinction law. With the template extinction laws self-contained, and the capability of revealing extinction laws differing from the conventional ones, it is shown that this is a powerful approach in modeling the afterglow SEDs to derive GRB host extinction.Comment: 9 pages, 4 figures; The Astrophysical Journal, in press (2008 Oct 1 issue

Evaluation of outcomes reported in randomized controlled trials for herbal remedies for adults with chronic hepatitis C

Background: Herbal remedies have been widely utilized in treating chronic hepatitis C (CHC) worldwide. Selecting appropriate outcomes to reflect both beneficial and harmful effects is a crucial step in designing randomized controlled trials (RCTs). This study evaluated the outcomes reported in RCTs on herbal remedies for CHC with comparison to the core outcomes recommended by the Cochrane Hepato-Biliary Group (CHBG), to check the consistency of the outcomes and to provide recommendation for future researches. Methods: A systematic literature search was conducted in Western and Chinese databases to identify RCTs on herbal remedies for adults with CHC. For each trial, all the outcomes reported in the results section were collected. Comparison between trial outcomes and CHBG core outcomes were evaluated and summarized with descriptive statistics. Results: A total of 116 RCTs involving 9154 participants were included; 27 outcomes were identified. Commonly reported outcomes included alanine aminotransferase (64 trials, 55.2%), adverse events (58 trials, 50.0%), and end-of-treatment virological response (50 trials, 43.1%). All trials indicated that the herbal remedies under investigation had a positive effect and was markedly more effective than the control. Nearly half of the trials reported that the combination of herbal medicine and antiviral drugs could ameliorate adverse events. Very few trials reported primary core outcomes relating survival and quality of life. The most frequently reported core outcomes are non-serious adverse events (54 trials, 46.6%), viral response (27 trials, 23.3%), and biochemical response (24 trials, 20.7%). Conclusion: The variation and inconsistency in trial outcomes impedes research synthesis efforts, and indicate the need for comparable outcomes through the development of core outcome sets in CHC. The low concordance of outcome reporting could be improved by following CHBG core outcomes recommendation

Semantic Object Parsing with Graph LSTM

By taking the semantic object parsing task as an exemplar application scenario, we propose the Graph Long Short-Term Memory (Graph LSTM) network, which is the generalization of LSTM from sequential data or multi-dimensional data to general graph-structured data. Particularly, instead of evenly and fixedly dividing an image to pixels or patches in existing multi-dimensional LSTM structures (e.g., Row, Grid and Diagonal LSTMs), we take each arbitrary-shaped superpixel as a semantically consistent node, and adaptively construct an undirected graph for each image, where the spatial relations of the superpixels are naturally used as edges. Constructed on such an adaptive graph topology, the Graph LSTM is more naturally aligned with the visual patterns in the image (e.g., object boundaries or appearance similarities) and provides a more economical information propagation route. Furthermore, for each optimization step over Graph LSTM, we propose to use a confidence-driven scheme to update the hidden and memory states of nodes progressively till all nodes are updated. In addition, for each node, the forgets gates are adaptively learned to capture different degrees of semantic correlation with neighboring nodes. Comprehensive evaluations on four diverse semantic object parsing datasets well demonstrate the significant superiority of our Graph LSTM over other state-of-the-art solutions.Comment: 18 page

Hepatitis C in Haematological Patients

There is no consensus guideline concerning the management of chronic hepatitis C patients during chemotherapy, and immunosuppression. However, there are some suggestions in literature that hepatitis C viral load increases during chemotherapy and there is a risk of rebound immunity against hepatitis C after discontinuation of immunosuppression with a consequent liver injury. A close monitoring of liver function of these patients is prudent during treatment of haematological malignancy. Antiviral treatment is deferred after the completion of chemotherapy and recovery of patients' immunity to minimize the toxicity of treatment. A combination of pegylated interferon and ribavirin is the standard therapy in hepatitis C infected haematological patients