1,778 research outputs found

    The Return To Tax Simplification: an Econometric Analysis

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    This article provides estimates of the probable saving in the resource cost of complying with the tax law that would result from simplifying the individual Abstract income tax law. These estimates are based on an econometric analysis of the tax-filing behavior in 1982 of a sample of Minnesota taxpayers. A simple model of tax-compliance behavior based on utility maximization is first presented in order to suggest the important determinants of compliance behavior. The empirical model treats the discrete choices of whether to itemize deductions and whether to hire professional tax advice, and the choice of how much time and money to spend, conditional on the discrete choices made. Simulations based on the econometric results suggest that significant resource saving could be expected from eliminating the system of itemized deductions, although no significant saving from changing to a single-rate tax structure can be confidently predicted. Results suggest that the Tax Reform Act of 1986 will, in the long run, decrease the use ofprofessional tax assistance, but its net effect on the use of taxpayer's own time is unclear.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68711/2/10.1177_109114218901700101.pd

    Differential Uptake of Gold Nanoparticles by 2 Species of Tadpole, the Wood Frog (Lithobates Sylvaticus) and the Bullfrog (Lithobates Catesbeianus)

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    Engineered nanoparticles are aquatic contaminants of emerging concern that exert ecotoxicological effects on a wide variety of organisms. We exposed cetyltrimethylammonium bromide–capped spherical gold nanoparticles to wood frog and bullfrog tadpoles with conspecifics and in combination with the other species continuously for 21 d, then measured uptake and localization of gold. Wood frog tadpoles alone and in combination with bullfrog tadpoles took up significantly more gold than bullfrogs. Bullfrog tadpoles in combination with wood frogs took up significantly more gold than controls. The rank order of weight-normalized gold uptake was wood frogs in combination \u3e wood frogs alone \u3e bullfrogs in combination \u3e bullfrogs alone \u3e controls. In all gold-exposed groups of tadpoles, gold was concentrated in the anterior region compared with the posterior region of the body. The concentration of gold nanoparticles in the anterior region of wood frogs both alone and in combination with bullfrogs was significantly higher than the corresponding posterior regions. We also measured depuration time of gold in wood frogs. After 21 d in a solution of gold nanoparticles, tadpoles lost \u3e83% of internalized gold when placed in gold-free water for 5 d. After 10 d in gold-free water, tadpoles lost 94% of their gold. After 15 d, gold concentrations were below the level of detection. Our finding of differential uptake between closely related species living in similar habitats with overlapping geographical distributions argues against generalizing toxicological effects of nanoparticles for a large group of organisms based on measurements in only one species

    Image Fusion for Computer Assisted Tumor Surgery (CATS)

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    Embedding a Native State into a Random Heteropolymer Model: The Dynamic Approach

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    We study a random heteropolymer model with Langevin dynamics, in the supersymmetric formulation. Employing a procedure similar to one that has been used in static calculations, we construct an ensemble in which the affinity of the system for a native state is controlled by a "selection temperature" T0. In the limit of high T0, the model reduces to a random heteropolymer, while for T0-->0 the system is forced into the native state. Within the Gaussian variational approach that we employed previously for the random heteropolymer, we explore the phases of the system for large and small T0. For large T0, the system exhibits a (dynamical) spin glass phase, like that found for the random heteropolymer, below a temperature Tg. For small T0, we find an ordered phase, characterized by a nonzero overlap with the native state, below a temperature Tn \propto 1/T0 > Tg. However, the random-globule phase remains locally stable below Tn, down to the dynamical glass transition at Tg. Thus, in this model, folding is rapid for temperatures between Tg and Tn, but below Tg the system can get trapped in conformations uncorrelated with the native state. At a lower temperature, the ordered phase can also undergo a dynamical glass transition, splitting into substates separated by large barriers.Comment: 19 pages, revtex, 6 figure

    Marek's Disease Virus Down-Regulates Surface Expression of MHC (B Complex) Class I (BF) Glycoproteins during Active but not Latent Infection of Chicken Cells

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    AbstractInfection of chicken cells with three Marek's disease virus (MDV) serotypes interferes with expression of the major histocompatibility complex (MHC or B complex) class I (BF) glycoproteins. BF surface expression is blocked after infection of OU2 cells with MDV serotypes 1, 2, and 3. MDV-induced T-cell tumors suffer a nearly complete loss of cell surface BF upon virus reactivation with 5-bromo-2′-deoxyuridine (BUdR). The recombinant virus (RB1BUS2gfpΔ) transforming the MDCC-UA04 cell line expresses green fluorescent protein (GFP) during the immediate early phase of viral gene expression. Of the UA04 cells induced to express the immediate early GFP, approximately 60% have reduced levels of BF expression. All of the reactivated UA04 and MSB1 tumor cells expressing the major early viral protein pp38 display reduced levels of BF. Thus, BF down-regulation begins in the immediate early phase and is complete by the early phase of viral gene expression. The intracellular pool of BF is not appreciably affected, indicating that the likely mechanism is a block in BF transport and not the result of transcriptional or translational regulation

    Operator mixing and three-point functions in N=4 SYM

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    We study the three-point functions between two BPS and one non-BPS local gauge invariant operators in N=4 Super Yang-Mills theory. In particular we show, in explicit 1-loop examples, that the operator mixing discussed in arXiv:0810.0499 plays an important role in the computations of the correlators and is necessary to cancel contributions that would violate the constraints following from the superconformal and the bonus U(1)_Y symmetries. We analyse the same type of correlators also at strong coupling by using the BMN limit of the AdS_5xS^5 string theory. Again the mixing between states with different types of impurities is crucial to ensure the cancellation of various amplitudes that would violate the constraints mentioned above. However, on the string side, we also find some examples of interactions between one non-BPS and two BPS states that do not satisfy expectations based on the superconformal and the bonus U(1)_Y symmetries.Comment: 28 pages, 5 figure

    Non-Abelian, Self-Dual Chern-Simons Vortices Coupled to Gravity

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    In this article we consider SU(2)SU(2) Chern-Simons/Higgs theory coupled to gravity in three-dimensions. It is shown that for a cylindrically symmetric vortex both the Einstein equations and the field equations can be reduced to a set of first-order Bogomol'nyi equations provided that we choose a specific eighth-order potential.Comment: 21 pages, LATEX, no figure

    Perturbative Expansion around the Gaussian Effective Action: The Background Field Method

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    We develop a systematic method of the perturbative expansion around the Gaussian effective action based on the background field method. We show, by applying the method to the quantum mechanical anharmonic oscillator problem, that even the first non-trivial correction terms greatly improve the Gaussian approximation.Comment: 16 pages, 3 eps figures, uses RevTeX and epsf. Errors in Table 1 are corrected and new references are adde

    A Model Behind the Standard Model

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    In spite of its many successes, the Standard Model makes many empirical assumptions in the Higgs and fermion sectors for which a deeper theoretical basis is sought. Starting from the usual gauge symmetry u(1)Ă—su(2)Ă—su(3)u(1) \times su(2) \times su(3) plus the 3 assumptions: (A) scalar fields as vielbeins in internal symmetry space \cite{framevec}, (B) the ``confinement picture'' of symmetry breaking \cite{tHooft,Banovici}, (C) generations as ``dual'' to colour \cite{genmixdsm}, we are led to a scheme which offers: (I) a geometrical significance to scalar fields, (II) a theoretical criterion on what scalar fields are to be introduced, (III) a partial explanation of why su(2)su(2) appears broken while su(3)su(3) confines, (IV) baryon-lepton number (B - L) conservation, (V) the standard electroweak structure, (VI) a 3-valued generation index for leptons and quarks, and (VII) a dynamical system with all the essential features of an earlier phenomenological model \cite{genmixdsm} which gave a good description of the known mass and mixing patterns of quarks and leptons including neutrino oscillations. There are other implications the consistency of which with experiment, however, has not yet been systematically explored. A possible outcome is a whole new branch of particle spectroscopy from su(2)su(2) confinement, potentially as rich in details as that of hadrons from colour confinement, which will be accessible to experiment at high energy.Comment: 66 pages, added new material on phenomenology, and some new reference

    Moduli Dynamics of AdS_3 Strings

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    We construct a general class of solutions for a classical string in AdS_3 spacetime. The construction is based on a Pohlmeyer type reduction, with the sinh-Gordon model providing the general N-soliton solutions. The corresponding exact spiky string configurations are then reconstructed through the inverse scattering method. It is shown that the string moduli are determined entirely by those of the solitons.Comment: 22 pages, no figures; references adde
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