129,237 research outputs found
Immature dendritic cells induce hyporesponsiveness to alloantigens in vitro and prolong mouse cardiac allograft survival
Identification and estimation of hedonic models
This paper considers the identification and estimation of hedonic models. We establish that in an additive version of the hedonic model, technology and preferences are generically nonparametrically identified from data on demand and supply in a single hedonic market. The empirical literature that claims that hedonic models estimated on data from a single market are fundamentally underidentified is based on arbitrary linearizations that do not use all the information in the model. The exact economic model that justifies linear approximations is unappealing. Nonlinearities are generic features of equilibrium in hedonic models and a fundamental and economically motivated source of identification
On the Performance Prediction of BLAS-based Tensor Contractions
Tensor operations are surging as the computational building blocks for a
variety of scientific simulations and the development of high-performance
kernels for such operations is known to be a challenging task. While for
operations on one- and two-dimensional tensors there exist standardized
interfaces and highly-optimized libraries (BLAS), for higher dimensional
tensors neither standards nor highly-tuned implementations exist yet. In this
paper, we consider contractions between two tensors of arbitrary dimensionality
and take on the challenge of generating high-performance implementations by
resorting to sequences of BLAS kernels. The approach consists in breaking the
contraction down into operations that only involve matrices or vectors. Since
in general there are many alternative ways of decomposing a contraction, we are
able to methodically derive a large family of algorithms. The main contribution
of this paper is a systematic methodology to accurately identify the fastest
algorithms in the bunch, without executing them. The goal is instead
accomplished with the help of a set of cache-aware micro-benchmarks for the
underlying BLAS kernels. The predictions we construct from such benchmarks
allow us to reliably single out the best-performing algorithms in a tiny
fraction of the time taken by the direct execution of the algorithms.Comment: Submitted to PMBS1
Improving supplementary feeding in species conservation
Supplementary feeding is often a knee-jerk reaction to population declines, and its application is not critically evaluated, leading to polarized views among managers on its usefulness. Here, we advocate a more strategic approach to supplementary feeding so that the choice to use it is clearly justified over, or in combination with, other management actions and the predicted consequences are then critically assessed following implementation. We propose combining methods from a set of specialist disciplines that will allow critical evaluation of the need, benefit, and risks of food supplementation. Through the use of nutritional ecology, population ecology, and structured decision making, conservation managers can make better choices about what and how to feed by estimating consequences on population recovery across a range of possible actions. This structured approach also informs targeted monitoring and more clearly allows supplementary feeding to be integrated in recovery plans and reduces the risk of inefficient decisions. In New Zealand, managers of the endangered Hihi (Notiomystis cincta) often rely on supplementary feeding to support reintroduced populations. On Kapiti island the reintroduced Hihi population has responded well to food supplementation, but the logistics of providing an increasing demand recently outstretched management capacity. To decide whether and how the feeding regime should be revised, managers used a structured decision making approach informed by population responses to alternative feeding regimes. The decision was made to reduce the spatial distribution of feeders and invest saved time in increasing volume of food delivered into a smaller core area. The approach used allowed a transparent and defendable management decision in regard to supplementary feeding, reflecting the multiple objectives of managers and their priorities
Accelerated HIV testing for PMTCT in maternity and labour wards is vital to capture mothers at a critical point in the programme at district level
TORONTO AIDS Conference 200
Novel methods of fabrication and metrology of superconducting nanostructures
As metrology extends toward the nanoscale, a number of potential applications and new challenges arise. By combining photolithography with focused ion beam and/or electron beam methods, superconducting quantum interference devices (SQUIDs) with loop dimensions down to 200 nm and superconducting bridge dimensions of the order 80 nm have been produced. These SQUIDs have a range of potential applications. As an illustration, we describe a method for characterizing the effective area and the magnetic penetration depth of a structured superconducting thin film in the extreme limit, where the superconducting penetration depth is much greater than the film thickness and is comparable with the lateral dimensions of the device
Costimulatory molecule-deficient dendritic cell progenitors induce T cell hyporesponsiveness in vitro and prolong the survival of vascularized cardiac allografts
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