13,712 research outputs found
UBVI Surface Photometry of the Spiral Galaxy NGC 300 in the Sculptor Group
We present UBVI surface photometry for 20.'5 X 20.'5 area of a late-type
spiral galaxy NGC 300. In order to understand the morphological properties and
luminosity distribution characteristics of NGC 300, we have derived isophotal
maps, surface brightness profiles, ellipticity profiles, position angle
profiles, and color profiles. By merging the I-band data of our surface
brightness measurements with those of Boeker et al. (2002) based on Hubble
Space Telescope observations, we have made combined I-band surface brightness
profiles for the region of 0."02 < r < 500" and decomposed the profiles into
three components: a nucleus, a bulge, and an exponential disk.Comment: 16 pages(cjaa209.sty), Accepted by the Chinese J. Astron. Astrophys.,
Fig 2 and 8 are degraded to reduce spac
A Spectral Line Survey from 138.3 to 150.7 GHZ toward Orion-KL
We present the results of a spectral line survey from 138.3 to 150.7 GHz
toward Orion-KL. The observations were made using the 14 m radio telescope of
Taeduk Radio Astronomy Observatory. Typical system temperatures were between
500 and 700 K, with the sensitivity between K in units of .
A total of 149 line spectra are detected in this survey. Fifty lines have
been previously reported, however we find 99 new detections. Among these new
lines, 32 are `unidentified', while 67 are from molecular transitions with
known identifications. There is no detection of H or He recombination lines.
The identified spectra are from a total of 16 molecular species and their
isotopic variants. In the range from 138.3 to 150.7 GHz, the strongest spectral
line is the J=3-2 transition of CS molecule, followed by transitions of the
, , , and . Spectral lines from
the large organic molecules such as , , , and are prominent; with 80 % of the
identified lines arising from transitions of these molecules. The rotational
temperatures and column densities are derived using the standard rotation
diagram analysis for (), , and with and . These estimates are fairly comparable to the values for the
same molecule in other frequency regions by other studies.Comment: 10 figures, 2 tex files for a manuscript and tables, accepted to Ap
Kink-induced transport and segregation in oscillated granular layers
We use experiments and molecular dynamics simulations of vertically
oscillated granular layers to study horizontal particle segregation induced by
a kink (a boundary between domains oscillating out of phase). Counter-rotating
convection rolls carry the larger particles in a bidisperse layer along the
granular surface to a kink, where they become trapped. The convection
originates from avalanches that occur inside the layer, along the interface
between solidified and fluidized grains. The position of a kink can be
controlled by modulation of the container frequency, making possible systematic
harvesting of the larger particles.Comment: 4 pages, 5 figures. to appear in Phys. Rev. Let
Tests of Lorentz violation in muon antineutrino to electron antineutrino oscillations
A recently developed Standard-Model Extension (SME) formalism for neutrino
oscillations that includes Lorentz and CPT violation is used to analyze the
sidereal time variation of the neutrino event excess measured by the Liquid
Scintillator Neutrino Detector (LSND) experiment. The LSND experiment,
performed at Los Alamos National Laboratory, observed an excess, consistent
with neutrino oscillations, of in a beam of . It
is determined that the LSND oscillation signal is consistent with no sidereal
variation. However, there are several combinations of SME coefficients that
describe the LSND data; both with and without sidereal variations. The scale of
Lorentz and CPT violation extracted from the LSND data is of order
GeV for the SME coefficients and . This solution for
Lorentz and CPT violating neutrino oscillations may be tested by other short
baseline neutrino oscillation experiments, such as the MiniBooNE experiment.Comment: 10 pages, 10 figures, 2 tables, uses revtex4 replaced with version to
be published in Physical Review D, 11 pages, 11 figures, 2 tables, uses
revtex
Remarks on Renormalization of Black Hole Entropy
We elaborate the renormalization process of entropy of a nonextremal and an
extremal Reissner-Nordstr\"{o}m black hole by using the Pauli-Villars
regularization method, in which the regulator fields obey either the
Bose-Einstein or Fermi-Dirac distribution depending on their spin-statistics.
The black hole entropy involves only two renormalization constants. We also
discuss the entropy and temperature of the extremal black hole.Comment: 14 pages, revtex, no figure
Spectroscopic Evidence for Anisotropic S-Wave Pairing Symmetry in MgB2
Scanning tunneling spectroscopy of superconducting MgB ( K)
were studied on high-density pellets and c-axis oriented films. The sample
surfaces were chemically etched to remove surface carbonates and hydroxides,
and the data were compared with calculated spectra for all symmetry-allowed
pairing channels. The pairing potential () is best described by an
anisotropic s-wave pairing model, with , where is the angle relative to the
crystalline c-axis, meV, and meV.Comment: 4 pages and 3 figures. Submitted to Physical Review Letters.
Corresponding author: Nai-Chang Yeh (e-mail: [email protected]
17β-Estradiol dysregulates innate immune responses to Pseudomonas aeruginosa respiratory infection and is modulated by estrogen receptor antagonism
ABSTRACT
Females have a more severe clinical course than males in terms of several inflammatory lung conditions. Notably, females with cystic fibrosis (CF) suffer worse outcomes, particularly in the setting of
Pseudomonas aeruginosa
infection. Sex hormones have been implicated in experimental and clinical studies; however, immune mechanisms responsible for this sex-based disparity are unknown and the specific sex hormone target for therapeutic manipulation has not been identified. The objective of this study was to assess mechanisms behind the impact of female sex hormones on host immune responses to
P. aeruginosa
. We used wild-type and CF mice, which we hormone manipulated, inoculated with
P. aeruginosa
, and then examined for outcomes and inflammatory responses. Neutrophils isolated from mice and human subjects were tested for responses to
P. aeruginosa
. We found that female mice inoculated with
P. aeruginosa
died earlier and showed slower bacterial clearance than males (
P
< 0.0001). Ovariectomized females supplemented with 17β-estradiol succumbed to
P. aeruginosa
challenge earlier than progesterone- or vehicle-supplemented mice (
P
= 0.0003). 17β-Estradiol-treated ovariectomized female mice demonstrated increased lung levels of inflammatory cytokines, and when rendered neutropenic the mortality difference was abrogated. Neutrophils treated with 17β-estradiol demonstrated an enhanced oxidative burst but decreased
P. aeruginosa
killing and earlier cell necrosis. The estrogen receptor (ER) antagonist ICI 182,780 improved survival in female mice infected with
P. aeruginosa
and restored neutrophil function. We concluded that ER antagonism rescues estrogen-mediated neutrophil dysfunction and improves survival in response to
P. aeruginosa
. ER-mediated processes may explain the sex-based mortality gap in CF and other inflammatory lung illnesses, and the ER blockade represents a rational therapeutic strategy.
</jats:p
- …