Moving-boundary problems solved by adaptive radial basis functions

The objective of this paper is to present an alternative approach to the conventional level set methods for solving two-dimensional moving-boundary problems known as the passive transport. Moving boundaries are associated with time-dependent problems and the position of the boundaries need to be determined as a function of time and space. The level set method has become an attractive design tool for tracking, modeling and simulating the motion of free boundaries in fluid mechanics, combustion, computer animation and image processing. Recent research on the numerical method has focused on the idea of using a meshless methodology for the numerical solution of partial differential equations. In the present approach, the moving interface is captured by the level set method at all time with the zero contour of a smooth function known as the level set function. A new approach is used to solve a convective transport equation for advancing the level set function in time. This new approach is based on the asymmetric meshless collocation method and the adaptive greedy algorithm for trial subspaces selection. Numerical simulations are performed to verify the accuracy and stability of the new numerical scheme which is then applied to simulate a bubble that is moving, stretching and circulating in an ambient flow to demonstrate the performance of the new meshless approach. (C) 2010 Elsevier Ltd. All rights reserved

Molecular epidemiology of MRSA in 13 ICUs from eight European countries

Objectives: The European epidemiology of MRSA is changing with the emergence of community-associated MRSA (CA-MRSA) and livestock-associated MRSA (LA-MRSA). In this study,we investigated the molecular epidemiology of MRSA during 2 years in 13 ICUs in France, Greece, Italy, Latvia, Luxemburg, Portugal, Slovenia and Spain. Methods: Surveillance cultures for MRSA from nose and wounds were obtained on admission and twice weekly from all patients admitted to an ICU for ≥3 days. The first MRSA isolate per patient was genotyped in a central laboratory by MLST, spa typing, agr typing and SCCmec (sub)typing. Risk factors for patients with an unknown history of MRSA colonization were identified. Results: Overall, 14390 ICU patients were screened, of whom 8519 stayed in an ICU for ≥3 days. Overall MRSA admission prevalence was 3.9% and ranged from 1.0% to 7.0% for individual ICUs. Overall MRSA acquisition rate was 2.5/1000 patient days at risk and ranged from 0.2 to 8/1000 patient days at risk per ICU. In total, 557 putative MRSA isolates were submitted to the central laboratory for typing, of which 511 (92%) were confirmed as MRSA. Each country had a distinct epidemiology, with ST8-IVc (UK-EMRSA-2/-6, USA500) being most prevalent, especially in France and Spain, and detected in ICUs in five of eight countries. Seventeen (3%) and three (70 years and hospitalization within 1 year prior to ICU admission. Conclusions: The molecular epidemiology of MRSA in 13 European ICUs in eight countries was homogeneous within, but heterogeneous between, countries. CA-MRSA and LA-MRSA genotypes and Panton-Valentine leucocidin-producing isolates were detected sporadically