3,961 research outputs found
Helen Oyeyemi and Border Identities: Contesting Western Representations of Immigrants through Transnational Literature
Oyeyemi is a Nigerian-British writer whose writing, like other immigrant authors\u27, participates in a dialogue about and contestation of essentialized immigrant and ethnic identities that are a result of global and local processes. Her writing produces counter-narratives in which immigrant identities are multiple, conflicting, intersectional, and most of all self-represented. This paper explores readings of Oyeyemi accompanied by the following: an examination of globalization and flows of migration; the connections of national epistemologies through media to processes like migration: how literary canon has excluded transnational fiction from the mainstream, thereby decreasing the ability of multi-ethnic and im/migrant writers to represent themselves successfully; and finally the literary shift into a more nuanced understanding of multiculturalism, diaspora, nations, and borders through persistent critiques and re-interpretations by minority writers
Reconciling Christianity and Paganism
In her novel Jane Eyre, Charlotte Bronte works to bring opposing ideas of Christianity and Paganism together to strengthen her protagonist, Jane. Bronte uses symbols of supernaturalism, nature, and the moon to highlight Jane\u27s complex spiritual growth. This essay explores those symbols in conjunction with Christianity and their influences on Jane Eyre as she becomes an empowered woman
Mitotic Cdc6 Stabilizes Anaphase-Promoting Complex Substrates by a Partially Cdc28-Independent Mechanism, and This Stabilization Is Suppressed by Deletion of Cdc55
Ectopic expression of Cdc6p results in mitotic delay, and this has been attributed to Cdc6p-mediated inhibition of Cdc28 protein kinase and failure to activate the anaphase-promoting complex (APC). Here we show that endogenous Cdc6p delays a specific subset of mitotic events and that Cdc28 inhibition is not sufficient to account for it. The depletion of Cdc6p in G2/M cells reveals that Cdc6p is rate limiting for the degradation of the APC/Cdc20 substrates Pds1p and Clb2p. Conversely, the premature expression of Cdc6p delays the degradation of APC/Cdc20 substrates. Abolishing Cdc6p/Cdc28p interaction does not eliminate the Cdc6-dependent delay of these anaphase events. To identify additional Cdc6-mediated, APC-inhibitory mechanisms, we looked for mutants that reversed the mitotic delay. The deletion of SWE1, RAD24, MAD2, or BUB2 had no effect. However, disrupting CDC55, a PP2A regulatory subunit, suppressed the Cdc6p-dependent delay of Pds1 and Clb2 destruction. A specific role for CDC55 was supported by demonstrating that the lethality of Cdc6 ectopic expression in a cdc16-264 mutant is suppressed by the deletion of CDC55, that endogenous Cdc6p coimmunoprecipitates with the Cdc55 and Tpd3 subunits of PP2A, that Cdc6p/Cdc55p/Tpd3 interaction occurs only during mitosis, and that Cdc6 affects PP2A-Cdc55 activity during anaphase. This demonstrates that the levels and timing of accumulation of Cdc6p in mitosis are appropriate for mediating the modulation of APC/Cdc20
Looking Forward, Looking Back: Reflections on Values and Pedagogical Choices During Covid-19
In this reflective essay, the author describes teaching a writing pedagogy course for secondary English education students during the Covid-19 pandemic. The author describes two different bodies of literature – ethics of care and high leverage practices -- and reflects how these concepts guided her pedagogical decision making when moving her class online on a short timeline
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