4 research outputs found
ΠΠΎΠ²ΡΠ΅ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΠΈ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ ΡΡΠΎΡΡ ΠΈΠ½ΠΎΠ»ΠΎΠ½ΠΎΠ² Π² ΠΏΡΠ»ΡΠΌΠΎΠ½ΠΎΠ»ΠΎΠ³ΠΈΠΈ
ΠΠΎΠ·ΠΎΠΊΠΎΠΌΠΈΠ°Π»ΡΠ½Π°Ρ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΡ Ρ Π²Π·ΡΠΎΡΠ»ΡΡ : ΠΏΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄Π°ΡΠΈΠΈ ΠΏΠΎ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠ΅, Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΈ ΠΏΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΠΊΠ΅. ΠΠΎΡΠΎΠ±ΠΈΠ΅ Π΄Π»Ρ Π²ΡΠ°ΡΠ΅ΠΉ
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ΠΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½ΠΈΡ Π²ΡΠ°ΡΠ΅ΠΉ ΠΏΠΎΠ»ΠΈΠΊΠ»ΠΈΠ½ΠΈΠΊ ΠΎΠ± ΡΡΠΈΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΈ ΡΠ°ΠΊΡΠΈΠΊΠ΅ Π»Π΅ΡΠ΅Π½ΠΈΡ Π²Π½Π΅Π±ΠΎΠ»ΡΠ½ΠΈΡΠ½ΠΎΠΉ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠΈ Π² Π°ΠΌΠ±ΡΠ»Π°ΡΠΎΡΠ½ΡΡ ΡΡΠ»ΠΎΠ²ΠΈΡΡ
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Problems of poststreptococcal diseases primary prophylaxis - lessons of a multicenter study management practice of patients with acute tonsillitis
Objective. To evaluate the actual practice of diagnostics and treatment of patients with acute tonsillitis in order to assess the quality of primary prophylaxis of poststreptococcal diseases in different regions of Russia. Material and methods. The medical charts of 1333 adult outpts with acute tonsillitis in seven cities were analyzed. The data on each pts such as demographics, case history, bacteriological examinations results, prescribed medications, adverse events and outcomes of therapy were documented in case record forms. Data management was carried out using software. Results. Microbiological identifications of group A-streptococcus (GAS) were performed only in 0,3% of analyzed cases, so diagnosis of tonsillitis was based commonly on clinical data. Systemic antimicrobial drugs were prescribed to 95,3% of pts, among them to 91,5% as monotherapy and to 3,8% as combined therapy. Ampicillin was the most often initial antimicrobial (45,0%), other relatively frequently prescribed drugs were erythomycin (19,1%), ciprofloxacin (7,0%), doxycycline (5,6%), amoxycillin (5,2%), midecamycin (4,4%), ampicillin/oxacillin (3,2%). Two courses of antimicrobials were used in 8,5% of pts. The average duration of antibacterial therapy was 7,4 Β± 3,4 days. The adverse events were noted in 0,9% of analyzed cases. Conclusion. The main problems of primary prophylaxis of poststreptococcal diseases were: (1) the diagnosis of tonsillitis without microbiological GAS identification, (2) prescribing antimicrobials without consideration of appropriate recommendation and (3) the lack of pathogen eradication control