Siger - orientações para interface gráfica.

Este documento tem por objetivo descrever as diretrizes para o projeto da interface de entrada de dados do Sistema de Informação Gerencial da Embrapa (SIGER), promovendo uma uniformidade visual dos elementos gráficos que o compoem. Como consequência desta uniformidade, espera-se que todo o SIGER possua o mesmo padrão de interface gráfica, o que irá facilitar a interacão do usuário com o sistema. São estabelecidas orientações para a disposição de elementos gráficos na tela e a definição de algumas das suas propriedades básicas. Algumas caracteristicas gerais do ambiente Windows sao mantidas na aplicação conforme a configuração definida pelo usuário, como exemplo cor das janelas ativa e inativa, texto da janela, texto da mensagem, cor do item de menu normal, desativado e selecionado.bitstream/item/76631/1/CNPTIA-COM.TEC.-4-98.pd

Avaliação da expansão da cana-de-açúcar em Mato Grosso do Sul (MS) analisando a relação entre o clima atual e a produtividade da cultura.

Este trabalho teve como objetivos relacionar os dados de temperatura e precipitação (2000 a 2010) com os dados de produtividade (área colhida e valor da produção), analisando a influência das alterações do clima atual na expansão da cana-de-açúcar em MS, e o de comparar a produtividade da cana-de-açúcar com a produtividade das culturas de soja e algodão

Targeting RAGE prevents muscle wasting and prolongs survival in cancer cachexia

Background: Cachexia, a multifactorial syndrome affecting more than 50% of patients with advanced cancer and responsible for ~20% of cancer-associated deaths, is still a poorly understood process without a standard cure available. Skeletal muscle atrophy caused by systemic inflammation is a major clinical feature of cachexia, leading to weight loss, dampening patients' quality of life, and reducing patients' response to anticancer therapy. RAGE (receptor for advanced glycation end-products) is a multiligand receptor of the immunoglobulin superfamily and a mediator of muscle regeneration, inflammation, and cancer. Methods: By using murine models consisting in the injection of colon 26 murine adenocarcinoma (C26-ADK) or Lewis lung carcinoma (LLC) cells in BALB/c and C57BL/6 or Ager−/− (RAGE-null) mice, respectively, we investigated the involvement of RAGE signalling in the main features of cancer cachexia, including the inflammatory state. In vitro experiments were performed using myotubes derived from C2C12 myoblasts or primary myoblasts isolated from C57BL/6 wild type and Ager−/− mice treated with the RAGE ligand, S100B (S100 calcium-binding protein B), TNF (tumor necrosis factor)α±IFN (interferon) γ, and tumour cell- or masses-conditioned media to analyse hallmarks of muscle atrophy. Finally, muscles of wild type and Ager−/− mice were injected with TNFα/IFNγ or S100B in a tumour-free environment. Results: We demonstrate that RAGE is determinant to activate signalling pathways leading to muscle protein degradation in the presence of proinflammatory cytokines and/or tumour-derived cachexia-inducing factors. We identify the RAGE ligand, S100B, as a novel factor able to induce muscle atrophy per se via a p38 MAPK (p38 mitogen-activated protein kinase)/myogenin axis and STAT3 (signal transducer and activator of transcription 3)-dependent MyoD (myoblast determination protein 1) degradation. Lastly, we found that in cancer conditions, an increase in serum levels of tumour-derived S100B and HMGB1 (high mobility group box 1) occurs leading to chronic activation/overexpression of RAGE, which induces hallmarks of cancer cachexia (i.e. muscle wasting, systemic inflammation, and release of tumour-derived pro-cachectic factors). Absence of RAGE in mice translates into reduced serum levels of cachexia-inducing factors, delayed loss of muscle mass and strength, reduced tumour progression, and increased survival. Conclusions: RAGE is a molecular determinant in inducing the hallmarks of cancer cachexia, and molecular targeting of RAGE might represent a therapeutic strategy to prevent or counteract the cachectic syndrome

Semi-automatic spline fitting of planar curvilinear profiles in digital images using the Hough transform

We develop a novel method for the recognition of curvilinear profiles in digital images. The proposed method, semi-automatic for both closed and open planar profiles, essentially consists of a preprocessing step exploiting an edge detection algorithm, and a main step involving the Hough transform technique. In the preprocessing step, a Canny edge detection algorithm is applied in order to obtain a reduced point set describing the profile curve to be reconstructed. Also, to identify in the profile possible sharp points like cusps, we additionally use an algorithm to find the approximated tangent vector of every edge point. In the subsequent main step, we then use a piecewisely defined Hough transform to locally recognize from the point set a low-degree piecewise polynomial curve. The final outcome of the algorithm is thus a spline curve approximating the underlined profile image. The output curve consists of polynomial pieces connected G^1 continuously, except in correspondence of the identified cusps, where the order of continu- ity is only C^0 , as expected. To illustrate effectiveness and efficiency of the new profile detection technique we present several numerical results dealing with detection of open and closed profiles in images of dif- ferent type, i.e., medical and photographic image

Comparativo do Plone com gerenciadores de conteúdo em PHP, Java e Python.

Definição e estrutura de CMS. Plataformas de desenvolvimento: PHP. Java. Python; Gerenciador de Conteúdo-Plone. Comparativo de Plone com outros gerenciadores.bitstream/CNPTIA/11048/1/doc55.pdfAcesso em: 29 maio 2008