11 research outputs found
Association of CXCL10 and CXCL13 levels with disease activity and cutaneous manifestation in active adult-onset Still’s disease
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Dendritic cells promote expansion and survival of aberrant TCR-negative intraepithelial lymphocyte lines from refractory celiac disease type II patients
No full textValidation of Gene Expression Biomarker Analysis for Biopsy-based Clinical Trials in Crohnʼs Disease
No full textA cross-ethnic survey of CFB and SLC44A4, Indian ulcerative colitis GWAS hits, underscores their potential role in disease susceptibility
No full textThe first ever genome-wide association study (GWAS) of ulcerative colitis in genetically distinct north Indian population identified two novel genes namely CFB and SLC44A4. Considering their biological relevance, we investigated allelic/genetic heterogeneity in these genes among ulcerative colitis cohorts of north Indian, Japanese and Dutch origin using high-density ImmunoChip case-control genotype data. Comparative linkage disequilibrium profiling and test of association were performed. Of the 28 CFB SNPs, similar strength of association was observed for rs4151657 (novel ulcerative colitis GWAS SNP) in north Indians (P=1.73 x 10(-10)) and Japanese (P= 2.02 x 10(-12)) but not in the Dutch. Further, a three-marker haplotype was shared between north Indians and Japanese (
Organizational Factors Related to Safety in a Psychiatric Hospital: Employee Perceptions
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City of Discontent? The Influence of Perceived Organizational Culture, LMX, and Newcomer Status on Reported Bullying in a Municipal Workplace
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