A study to determine the incidence and prevalence of newly discovered human immunodeficiency virus infection during the prenatal care period.

OBJECTIVES: This study asked the following questions: 1) Does HIV testing in pregnancy identify women who previously were not known to be HIV positive? 2) When in pregnancy are women identified as HIV infected? 3) Does HIV seroconversion occur during the prenatal care period? METHODS: Medical records of 97 women from two primarily indigent care hospitals in Houston, TX who were found to be HIV positive at delivery were reviewed to determine if they had tested positive during the prenatal care period. Demographics and time of gestation of the prenatal testing also were recorded. The outcome measures were: 1) number of women found positive during prenatal care; 2) week of gestation at discovery of HIV positivity; and 3) number of women seroconverting between the initiation of prenatal care and delivery. RESULTS: Thirty women were known to be HIV positive prior to pregnancy. Fifty-six women were found to be positive during prenatal care and the seropositivity of 44 was discovered before the 34th week of pregnancy. Ten women were found to be positive at their first prenatal visit, which occurred after the 34th week. Date of testing was unknown for two women. Eleven women who received no prenatal care were found to be HIV positive at delivery. There were no seroconversions while women were under prenatal care. CONCLUSIONS: HIV testing at delivery did not find any HIV-positive women who had tested negative during prenatal care. Testing is very important for women who do not receive prenatal care. Making certain that high-risk women get into prenatal care also is very important

Sleight of Hand: Identifying Concealed Information by Monitoring Mouse-Cursor Movements

Organizational members who conceal information about adverse behaviors present a substantial risk to that organization. Yet the task of identifying who is concealing information is extremely difficult, expensive, error-prone, and time-consuming. We propose a unique methodology for identifying concealed information: measuring people’s mouse-cursor movements in online screening questionnaires. We theoretically explain how mouse-cursor movements captured during a screening questionnaire differ between people concealing information and truth tellers. We empirically evaluate our hypotheses using an experiment during which people conceal information about a questionable act. While people completed the screening questionnaire, we simultaneously collected mouse-cursor movements and electrodermal activity—the primary sensor used for polygraph examinations—as an additional validation of our methodology. We found that mouse-cursor movements can significantly differentiate between people concealing information and people telling the truth. Mouse-cursor movements can also differentiate between people concealing information and truth tellers on a broader set of comparisons relative to electrodermal activity. Both mouse-cursor movements and electrodermal activity have the potential to identify concealed information, yet mouse-cursor movements yielded significantly fewer false positives. Our results demonstrate that analyzing mouse-cursor movements has promise for identifying concealed information. This methodology can be automated and deployed online for mass screening of individuals in a natural setting without the need for human facilitators. Our approach further demonstrates that mouse-cursor movements can provide insight into the cognitive state of computer users

Fission product behavior in the Molten Salt Reactor Experiment

Essentially all the fission product data for numerous and varied samples taken during operation of the Molten Salt Reactor Experiment or as part of the examination of specimens removed after particular phases of operation are reported, together with the appropriate inventory or other basis of comparison, and relevant reactor parameters and conditions. Fission product behavior fell into distinct chemical groups. Evidence for fission product behavior during operation over a period of 26 months with $sup 235$U fuel (more than 9000 effective full-power hours) was consistent with behavior during operation using $sup 233$U fuel over a period of about 15 months (more than 5100 effective full- power hours). (auth

Development of a high throughput, molecular diagnostic assay for predicting telomerase activity in breast cancer cell lines and tissues

Telomerase is a cellular enzyme that helps to provide genomic stability in tumor cells by maintaining the integrity of telomeres. Telomerase is an RNA-dependent DNA polymerase that contains a protein component (hTERT) and an associated RNA (hTR), which is used as a template for telomere repeat addition. Telomerase activity, while not detectable in most normal human somatic cells, is associated with approximately 85% of malignant human cancers overall, including over 90% of breast cancers. We have optimized a novel, quantitative, high-throughput telomerase activity assay using fluorescently labelled primers and Real Time quantitation via the ABI Prism 7700 (a.k.a., the TaqMan). Using established breast cancer cell lines and a subset of breast tumors, we demonstrate that telomerase levels quantitated from the TaqMan-based assay closely correlate with values obtained using the traditional, gel-based telomerase activity assay (TRAP). In addition, we have assessed the levels of both hTERT mRNA and hTR in each of our samples via RT-PCR to determine whether relative amounts or a ratio of the two telomerase components correlate with activity in a given sample. Our ultimate goal is to develop a Real Time, fluorescent RT-PCR assay to simultaneously measure hTERT and hTR messages in breast tumor samples, in an attempt to convert the enzymatic telomerase activity assay into a quantitative nucleic acid test to predict levels of activity in routinely processed clinical specimens

Parent-child interaction in Nigerian families: conversation analysis, context and culture

This paper uses a conversation analysis (CA) approach to explore parent child interaction (PCI) within Nigerian families. We illustrate how speech and language therapists (SLTs), by using CA, can tailor recommendations according to the interactional style of each individual family that are consonant with the family’s cultural beliefs. Three parent-child dyads were videoed playing and talking together in their home environments. The analysis uncovered a preference for instructional talk similar to that used in the classroom. Closer examination revealed that this was not inappropriate when considering the context of the activities and their perceived discourse role. Furthermore, this was not necessarily at the expense of responsivity or semantic contingency. The preference for instructional talk appeared to reflect deeply held cultural beliefs about the role of adults and children within the family and it is argued that the cultural paradigm is vitally important to consider when evaluating PCI. Given a potential risk that such young children may be vulnerable in terms of language difficulties, we offer an example of how PCI can be enhanced to encourage language development without disrupting the naturally occurring talk or the underlying purpose of the interaction

The X-ray emission of the most luminous 3CR radio sources

We investigate the X-ray properties of the most luminous radio sources in the 3CR catalogue, in order to assess if they are similar to the most luminous radio quiet quasars, for instance in the X-ray normalization with respect to the optical luminosity, or in the distribution of the absorption column density. We have selected the (optically identified) 3CR radio sources whose 178-MHz monochromatic luminosity lies in the highest factor-of-three bin. The 4 most luminous objects had already been observed in X rays. Of the remaining 16, we observed with XMM-Newton 4 randomly chosen, optical type 1s, and 4 type 2s. All targets have been detected. The optical-to-Xray spectral index, alphaox, can be computed only for the type 1s and, in agreement with previous studies, is found to be flatter than in radio quiet quasars of similar luminosity. However, the Compton thin type 2s have an absorption corrected X-ray luminosity systematically lower than the type 1s, by a factor which makes them consistent with the radio quiet alphaox. Within the limited statistics, the Compton thick objects seem to have a reflected component more luminous than the Compton thin ones. The extra X-ray component observed in type 1 radio loud quasars is beamed for intrinsic causes, and is not collimated by the absorbing torus as is the case for the (intrinsically isotropic) disk emission. The extra component can be associated with a relativistic outflow, provided that the flow opening angle and the Doppler beaming factor are 1/5 - 1/7 radians.Comment: LaTex, 6 pages, 3 figures, 3 tables; accepted for publication in A&

Radio-Continuum study of the Nearby Sculptor Group Galaxies. Part 1: NGC 300 at lambda = 20 cm

A series of new radio-continuum (lambda=20 cm) mosaic images focused on the NGC 300 galactic system were produced using archived observational data from the VLA and/or ATCA. These new images are both very sensitive (rms=60 microJy) and feature high angular resolution (<10"). The most prominent new feature is the galaxy's extended radio-continuum emission, which does not match its optical appearance. Using these newly created images a number of previously unidentified discrete sources have been discovered. Furthermore, we demonstrate that a joint deconvolution approach to imaging this complete data-set is inferior when compared to an immerge approach.Comment: 13 pages, 12 figures, accepted to APSS, new version to correct the missing reference

High Temperature Electron Localization in dense He Gas

We report new accurate mesasurements of the mobility of excess electrons in high density Helium gas in extended ranges of temperature $[(26\leq T\leq 77) K ]$ and density $[ (0.05\leq N\leq 12.0) {atoms} \cdot {nm}^{-3}]$ to ascertain the effect of temperature on the formation and dynamics of localized electron states. The main result of the experiment is that the formation of localized states essentially depends on the relative balance of fluid dilation energy, repulsive electron-atom interaction energy, and thermal energy. As a consequence, the onset of localization depends on the medium disorder through gas temperature and density. It appears that the transition from delocalized to localized states shifts to larger densities as the temperature is increased. This behavior can be understood in terms of a simple model of electron self-trapping in a spherically symmetric square well.Comment: 23 pages, 13 figure

Diffusion Quantum Monte Carlo Calculations of Excited States of Silicon

The band structure of silicon is calculated at the Gamma, X, and L wave vectors using diffusion quantum Monte Carlo methods. Excited states are formed by promoting an electron from the valence band into the conduction band. We obtain good agreement with experiment for states around the gap region and demonstrate that the method works equally well for direct and indirect excitations, and that one can calculate many excited states at each wave vector. This work establishes the fixed-node DMC approach as an accurate method for calculating the energies of low lying excitations in solids.Comment: 5 pages, 1 figur