688 research outputs found
Wrapped Magnetized Branes: Two Alternative Descriptions?
We discuss two inequivalent ways for describing magnetized D-branes wrapped N
times on a torus T^2. The first one is based on a non-abelian gauge bundle
U(N), while the second one is obtained by means of a Narain T-duality
transformation acting on a theory with non-magnetized branes. We construct in
both descriptions the boundary state and the open string vertices and show that
they give rise to different string amplitudes. In particular, the description
based on the gauge bundle has open string vertex operators with momentum
dependent Chan-Paton factors.Comment: 60 pages, LaTe
The open story of the magnetic fluxes
We discuss the effects of oblique internal magnetic fields on the spectrum of
type I superstrings compactified on tori. In particular we derive general
formulae for the magnetic shifts and multiplicities of open strings connecting
D9-branes with arbitrary magnetic fluxes. We discuss the flux induced potential
and offer an interpretation of the stabilization of R-R moduli associated to
deformations of the complex structure of T^6 in terms of non-derivative mixing
with NS-NS moduli. Finally we briefly comment on how to extract other low
energy couplings and generalize our results to toroidal orbifolds and other
configurations governed by rational conformal field theories on the worldsheet.Comment: 36 pages, LaTeX, References adde
Gauge thresholds in the presence of oblique magnetic fluxes
We compute the one-loop partition function and analyze the conditions for
tadpole cancellation in type I theories compactified on tori in the presence of
internal oblique magnetic fields. We check open - closed string channel duality
and discuss the effect of T-duality. We address the issue of the quantum
consistency of the toroidal model with stabilized moduli recently proposed by
Antoniadis and Maillard (AM). We then pass to describe the computation of
one-loop threshold corrections to the gauge couplings in models of this kind.
Finally we briefly comment on coupling unification and dilaton stabilization in
phenomenologically more viable modelsComment: 34 pages, 2 figures; references added, major changes to the
discussion of the model proposed by Antoniadis and Maillar
Active nuclear import and cytoplasmic retention of activation-induced deaminase
The enzyme activation-induced deaminase (AID) triggers antibody diversification in B cells by catalyzing deamination and consequently mutation of immunoglobulin genes. To minimize off-target deamination, AID is restrained by several regulatory mechanisms including nuclear exclusion, thought to be mediated exclusively by active nuclear export. Here we identify two other mechanisms involved in controlling AID subcellular localization. AID is unable to passively diffuse into the nucleus, despite its small size, and its nuclear entry requires active import mediated by a conformational nuclear localization signal. We also identify in its C terminus a determinant for AID cytoplasmic retention, which hampers diffusion to the nucleus, competes with nuclear import and is crucial for maintaining the predominantly cytoplasmic localization of AID in steady-state conditions. Blocking nuclear import alters the balance between these processes in favor of cytoplasmic retention, resulting in reduced isotype class switching.This
work was supported by the Canadian Institutes of Health Research (MOP 84543)
and a Canada Research Chair (to J.M.D.). A.O. was supported by a fellowship
from the Canadian Institutes of Health Research Cancer Training Program at the
IRCM. V.A.C. was supported in part by a Michel Saucier fellowship from the
Louis-Pasteur Canadian Fund through the University of Montreal
Multiplicity dependence of jet-like two-particle correlations in p-Pb collisions at = 5.02 TeV
Two-particle angular correlations between unidentified charged trigger and
associated particles are measured by the ALICE detector in p-Pb collisions at a
nucleon-nucleon centre-of-mass energy of 5.02 TeV. The transverse-momentum
range 0.7 5.0 GeV/ is examined,
to include correlations induced by jets originating from low
momen\-tum-transfer scatterings (minijets). The correlations expressed as
associated yield per trigger particle are obtained in the pseudorapidity range
. The near-side long-range pseudorapidity correlations observed in
high-multiplicity p-Pb collisions are subtracted from both near-side
short-range and away-side correlations in order to remove the non-jet-like
components. The yields in the jet-like peaks are found to be invariant with
event multiplicity with the exception of events with low multiplicity. This
invariance is consistent with the particles being produced via the incoherent
fragmentation of multiple parton--parton scatterings, while the yield related
to the previously observed ridge structures is not jet-related. The number of
uncorrelated sources of particle production is found to increase linearly with
multiplicity, suggesting no saturation of the number of multi-parton
interactions even in the highest multiplicity p-Pb collisions. Further, the
number scales in the intermediate multiplicity region with the number of binary
nucleon-nucleon collisions estimated with a Glauber Monte-Carlo simulation.Comment: 23 pages, 6 captioned figures, 1 table, authors from page 17,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/161
Multi-particle azimuthal correlations in p-Pb and Pb-Pb collisions at the CERN Large Hadron Collider
Measurements of multi-particle azimuthal correlations (cumulants) for charged
particles in p-Pb and Pb-Pb collisions are presented. They help address the
question of whether there is evidence for global, flow-like, azimuthal
correlations in the p-Pb system. Comparisons are made to measurements from the
larger Pb-Pb system, where such evidence is established. In particular, the
second harmonic two-particle cumulants are found to decrease with multiplicity,
characteristic of a dominance of few-particle correlations in p-Pb collisions.
However, when a gap is placed to suppress such correlations,
the two-particle cumulants begin to rise at high-multiplicity, indicating the
presence of global azimuthal correlations. The Pb-Pb values are higher than the
p-Pb values at similar multiplicities. In both systems, the second harmonic
four-particle cumulants exhibit a transition from positive to negative values
when the multiplicity increases. The negative values allow for a measurement of
to be made, which is found to be higher in Pb-Pb collisions at
similar multiplicities. The second harmonic six-particle cumulants are also
found to be higher in Pb-Pb collisions. In Pb-Pb collisions, we generally find
which is indicative of a Bessel-Gaussian
function for the distribution. For very high-multiplicity Pb-Pb
collisions, we observe that the four- and six-particle cumulants become
consistent with 0. Finally, third harmonic two-particle cumulants in p-Pb and
Pb-Pb are measured. These are found to be similar for overlapping
multiplicities, when a gap is placed.Comment: 25 pages, 11 captioned figures, 3 tables, authors from page 20,
published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/87
HIV infection of non-dividing cells: a divisive problem
Understanding how lentiviruses can infect terminally differentiated, non-dividing cells has proven a very complex and controversial problem. It is, however, a problem worth investigating, for it is central to HIV-1 transmission and AIDS pathogenesis. Here I shall attempt to summarise what is our current understanding for HIV-1 infection of non-dividing cells. In some cases I shall also attempt to make sense of controversies in the field and advance one or two modest proposals
Inclusive J/ψ production at forward and backward rapidity in p-Pb collisions at √sNN=8.16 TeV
Inclusive J/psi production is studied in p-Pb interactions at a centre-of-mass
energy per nucleon-nucleon collision sqrt(s_NN) = 8.16TeV, using the ALICE detector at the
CERN LHC. The J/psi meson is reconstructed, via its decay to a muon pair, in the centre-of-mass
rapidity intervals 2.03 < ycms < 3.53 and -4.46 < ycms < -2.96, where positive
and negative ycms refer to the p-going and Pb-going direction, respectively. The transverse
momentum coverage is pT < 20 GeV/c. In this paper, ycms- and pT-differential cross
sections for inclusive J/psi production are presented, and the corresponding nuclear modification
factors RpPb are shown. Forward results show a suppression of the J/psi yield with
respect to pp collisions, concentrated in the region pT < 5 GeV/c. At backward rapidity
no significant suppression is observed. The results are compared to previous measurements
by ALICE in p-Pb collisions at sqrt(s_NN) = 5.02TeV and to theoretical calculations. Finally,
the ratios RFB between forward- and backward-ycms RpPb values are shown and discussed
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