347 research outputs found

    An Audible Demonstration Of The Speed Of Sound In Bubbly Liquids

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    The speed of sound in a bubbly liquid is strongly dependent upon the volume fraction of the gas phase, the bubble size distribution, and the frequency of the acoustic excitation. At sufficiently low frequencies, the speed of sound depends primarily on the gas volume fraction. This effect can be audibly demonstrated using a one-dimensional acoustic waveguide, in which the flow rate of air bubbles injected into a water-filled tube is varied by the user. The normal modes of the waveguide are excited by the sound of the bubbles being injected into the tube. As the flow rate is varied, the speed of sound varies as well, and hence, the resonance frequencies shift. This can be clearly heard through the use of an amplified hydrophone and the user can create aesthetically pleasing and even musical sounds. In addition, the apparatus can be used to verify a simple mathematical model known as Wood's equation that relates the speed of sound of a bubbly liquid to its void fraction. (c) 2008 American Association of Physics Teachers.Mechanical Engineerin

    Preliminary evaluation of spectral, normal and meteorological crop stage estimation approaches

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    Several of the projects in the AgRISTARS program require crop phenology information, including classification, acreage and yield estimation, and detection of episodal events. This study evaluates several crop calendar estimation techniques for their potential use in the program. The techniques, although generic in approach, were developed and tested on spring wheat data collected in 1978. There are three basic approaches to crop stage estimation: historical averages for an area (normal crop calendars), agrometeorological modeling of known crop-weather relationships agrometeorological (agromet) crop calendars, and interpretation of spectral signatures (spectral crop calendars). In all, 10 combinations of planting and biostage estimation models were evaluated. Dates of stage occurrence are estimated with biases between -4 and +4 days while root mean square errors range from 10 to 15 days. Results are inconclusive as to the superiority of any of the models and further evaluation of the models with the 1979 data set is recommended

    Particle separation by phase modulated surface acoustic waves

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    High efficiency isolation of cells or particles from a heterogeneous mixture is a critical processing step in lab-on-a-chip devices. Acoustic techniques offer contactless and label-free manipulation, preserve viability of biological cells, and provide versatility as the applied electrical signal can be adapted to various scenarios. Conventional acoustic separation methods use time-of-flight and achieve separation up to distances of quarter wavelength with limited separation power due to slow gradients in the force. The method proposed here allows separation by half of the wavelength and can be extended by repeating the modulation pattern and can ensure maximum force acting on the particles. In this work, we propose an optimised phase modulation scheme for particle separation in a surface acoustic wave microfluidic device. An expression for the acoustic radiation force arising from the interaction between acoustic waves in the fluid was derived. We demonstrated, for the first time, that the expression of the acoustic radiation force differs in surface acoustic wave and bulk devices, due to the presence of a geometric scaling factor. Two phase modulation schemes are investigated theoretically and experimentally. Theoretical findings were experimentally validated for different mixtures of polystyrene particles confirming that the method offers high selectivity. A Monte-Carlo simulation enabled us to assess performance in real situations, including the effects of particle size variation and non-uniform acoustic field on sorting efficiency and purity, validating the ability to separate particles with high purity and high resolution

    An integrated microfluidic chip with 40 MHz lead-free transducer for fluid analysis

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    The design, fabrication, and evaluation of a high-frequency transducer made from lead-free piezoceramic for the application of microfluidic analysis is described. Barium strontium zirconate titanate [(Ba₀. ₉ ₅Sr₀. ₀ ₅)(Zr₀. ₀ ₅Ti₀.₉₅)O₃, abbreviated as BSZT] ceramic has been chosen to be the active element of the transducer. The center frequency and bandwidth of this high-frequency ultrasound transducer have been measured to be 43 MHz and 56.1%, respectively. The transducer was integrated into a microfluidic channel and used to measure the sound velocity and attenuation of the liquid flowing in the channel. Results suggest that lead-free high-frequency transducers could be used for in situ analysis of property of the fluid flowing through the microfluidic system.Department of Applied PhysicsAuthor name used in this publication: S. T. F. LeeAuthor name used in this publication: K. H. LamAuthor name used in this publication: L. LeiAuthor name used in this publication: X. M. ZhangAuthor name used in this publication: H. L. W. Cha

    Carrier-wave steepened pulses and gradient-gated high-order harmonic generation using linear ramp waveforms

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    We show how to optimize the process of high-harmonic generation (HHG) by gating the interaction using the field gradient of a driving pulse with a linear ramp waveform. Since maximized field gradients are efficiently generated by self-steepening processes, we first present a generalized theory of optical carrier-wave self-steepened (CSS) pulses. This goes beyond existing treatments, which only consider third-order nonlinearity, and has the advantage of describing pulses whose wave forms have a range of symmetry properties. Although a fertile field for theoretical work, CSS pulses are difficult to realize experimentally because of the deleterious effect of dispersion. We therefore consider synthesizing CSS-like profiles using a suitably phased sub-set of the harmonics present in a true CSS wave form. Using standard theoretical models of HHG, we show that the presence of gradient-maximized regions on the wave forms can raise the spectral cut-off and so yield shorter attosecond pulses. We study how the quality of the attosecond bursts created by spectral filtering depends on the number of harmonics included in the driving pulse.Comment: 8 pages, 10 figures; with appendix not present in published versio

    Investigation of a lattice Boltzmann model with a variable speed of sound

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    A lattice Boltzmann model is considered in which the speed of sound can be varied independently of the other parameters. The range over which the speed of sound can be varied is investigated and good agreement is found between simulations and theory. The onset of nonlinear effects due to variations in the speed of sound is also investigated and good agreement is again found with theory. It is also shown that the fluid viscosity is not altered by changing the speed of sound

    Acute inhibition of MEK suppresses congenital melanocytic nevus syndrome in a murine model driven by activated NRAS and Wnt signaling

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    Congenital melanocytic nevus (CMN) syndrome is the association of pigmented melanocytic nevi with extra-cutaneous features, classically melanotic cells within the central nervous system, most frequently caused by a mutation of NRAS codon 61. This condition is currently untreatable and carries a significant risk of melanoma within the skin, brain, or leptomeninges. We have previously proposed a key role for Wnt signaling in the formation of melanocytic nevi, suggesting that activated Wnt signaling may be synergistic with activated NRAS in the pathogenesis of CMN syndrome. Some familial pre-disposition suggests a germ-line contribution to CMN syndrome, as does variability of neurological phenotypes in individuals with similar cutaneous phenotypes. Accordingly, we performed exome sequencing of germ-line DNA from patients with CMN to reveal rare or undescribed Wnt-signaling alterations. A murine model harboring activated NRASQ61K and Wnt signaling in melanocytes exhibited striking features of CMN syndrome, in particular neurological involvement. In the first model of treatment for this condition, these congenital, and previously assumed permanent, features were profoundly suppressed by acute post-natal treatment with a MEK inhibitor. These data suggest that activated NRAS and aberrant Wnt signaling conspire to drive CMN syndrome. Post-natal MEK inhibition is a potential candidate therapy for patients with this debilitating condition

    Experiments on the Low Frequency Barrier Characteristics of Cellular Metamaterial Panels in a Diffuse Sound Field

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    The metamaterial under investigation here consists of a periodic arrangement of unit plates in a grid-like frame such that there is a contrast in the local areal mass between cell interior and cell wall. In the low frequency range and under normal incidence this metamaterial panel exhibits a sound transmission loss significantly larger than the transmission loss of an unstructured panel with the same homogeneous mass per unit area. However, when the incident sound field is diffuse, the relative advantage of the metamaterial barrier is reduced or eliminated. A sequence of experiments is documented to demonstrate that the relative advantage of the metamaterial barrier can be realized even in a diffuse sound field by creating a hybrid barrier system which embeds the metamaterial layer between a normalizing waveguide layer on the incident side and an absorbing layer on the transmitted side. The sound normalizing waveguide layer is a lattice structure, and the absorbing layer is high performance glass fiber mat. By using measurements of the transmission loss of a 1,2 m square panel system the role of each of these components is demonstrated
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