1,475 research outputs found

    A class of extremising sphere-valued maps with inherent maximal tori symmetries in SO(n)

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    In this paper we consider an energy functional depending on the norm of the gradient and seek to extremise it over an admissible class of Sobolev maps defined on an annulus and taking values on the unit sphere whilst satisfying suitable boundary conditions. We establish the existence of an infinite family of solutions with certain symmetries to the associated nonlinear Euler-Lagrange system in even dimensions and discuss the stability of such extremisers by way of examining the positivity of the second variation of the energy at these solutions

    Space shuttle electromagnetic environment experiment. Phase A: Definition study

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    A program is discussed which develops a concept for measuring the electromagnetic environment on earth with equipment on board an orbiting space shuttle. Earlier work on spaceborne measuring experiments is reviewed, and emissions to be expected are estimated using, in part, previously gathered data. General relations among system parameters are presented, followed by a proposal on spatial and frequency scanning concepts. The methods proposed include a nadir looking measurement with small lateral scan and a circularly scanned measurement looking tangent to the earth's surface at the horizon. Antenna requirements are given, assuming frequency coverage from 400 MHz to 40 GHz. For the low frequency range, 400-1000 MHz, a processed, thinned array is proposed which will be more fully analyzed in the next phase of the program. Preliminary hardware and data processing requirements are presented

    Some Aspects of Australian Universities for Chinese Universities to Consider

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    Several universities in Australia and in western China were investigated and compared together. Different aspects including equipment and facilities, arrangement of office and arrangement of laboratory, class scheduling, relationship between staff and students were considered to investigate differences between western Chinese and Australian universities. These parameters being investigated are seemingly trivial, subordinate and seldom been noticed by the public but it can quickly and greatly influence the humanity environment of campus and academic atmosphere. To do this study, Chinese economic factors and custom environment that caused these differences had been analyzed. Finally, it is pointed out some aspects of Australian universities that might be useful to be implemented in Chinese universities.Wang Yong Yin, Taheri Abbas, Liu Ping, Pan Qi Zh

    Square-root Nyquist filter design for QAM-based filter bank multicarrier systems

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    Filter bank multicarrier systems with quadrature amplitude modulation (FBMC/QAM) have drawn attentions to get the advantage of complex symbol transmission, as well as very low out of band radiation and relaxed synchronization requirements for asynchronous scenarios. In order to make this system viable for practical deployment, the biggest challenge is designing appropriate filters to minimize the interference between adjacent subcarriers, while maintaining the Nyquist property of the filter. We show that the deviation from the Nyquist property can be compensated through the fractional shift of the filtered symbols, which provides flexibility to optimize the stopband of the filter. The proposed design method shows advantages over the state of the art designs, and provides guidance for the filter design in practical FBMC/QAM systems

    Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-alpha in the Rat

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    Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-alpha (TNF-a) is involved in BBB injury and edema formation through a mechanism involving matrix metalloproteinase (MMP) upregulation. There is emerging evidence indicating that cyclooxygenase (COX) inhibition limits BBB disruption following ischemic stroke and bacterial meningitis, but the mechanisms involved are not known. We used intracerebral injection of TNF-a to study the effect of COX inhibition on TNF-a-induced BBB breakdown, MMP expression/activity and oxidative stress. BBB disruption was evaluated by the uptake of 14C-sucrose into the brain and by magnetic resonance imaging (MRI) utilizing Gd-DTPA as a paramagnetic contrast agent. Using selective inhibitors of each COX isoform, we found that COX-1 activity is more important than COX-2 in BBB opening. TNF-a induced a significant upregulation of gelatinase B (MMP-9), stromelysin-1 (MMP-3) and COX-2. In addition, TNF-a significantly depleted glutathione as compared to saline. Indomethacin (10 mg/kg; i.p.), an inhibitor of COX-1 and COX-2, reduced BBB damage at 24 h. Indomethacin significantly attenuated MMP-9 and MMP-3 expression and activation, and prevented the loss of endogenous radical scavenging capacity following intracerebral injection of TNF-a. Our results show for the first time that BBB disruption during neuroinflammation can be significantly reduced by administration of COX inhibitors. Modulation of COX in brain injury by COX inhibitors or agents modulating prostaglandin E2 formation/signaling may be useful in clinical settings associated with BBB disruption

    Evaluation of the chemical composition and in vitro antimicrobial activity of Rosmarinus officinalis, Zataria multiflora, Anethum graveolens and Eucalyptus globulus against Streptococcus iniae; the cause of zoonotic disease in farmed fish

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    There is a growing interest of industry to replace synthetic chemicals by natural products with bioactive properties from plant origin. The purpose of this study was to elucidate the factors affecting antimicrobial effectiveness of essential oils Rosmarinus officinalis, Zataria multiflora, Anethum graveolens and Eucalyptus globulus against food spoilage and pathogenic bacteria, Streptococcus iniae; the cause of zoonotic streptococcosis in fish. Food conservation is based on an intermittent search for foods with a high nutritional quality and microbial stability and it has been reached by the control of the growth/survival of spoiling and pathogen foodborne microorganisms. Based on several reports, fish streptococcosis is currently considered as one of the main limiting factors in the aquaculture industry, due to the significant economic losses (annually more than $150 million) that these infections cause in different cultured fresh and seawater fish species worldwide. The sensitivity of S. iniae to antibacterial activity of the essential oils was determined using well diffusion assays and paper disc diffusion method. The ranges of minimum inhibitory concentration (MIC) of the oils and extracts were 3.9-250 and 7.8-500 µg/ml and the ranges of minimum bactericidal concentration (MBC) values for the oils and extracts were found to be in the range of 7.8-250 and 15.6-500 µg/ml, respectively. The essential oils exhibited antibacterial activity against S. iniae. The essential oil of rosemary showed the strongest antimicrobial activity

    Electric-field-induced nematic-cholesteric transition and 3-D director structures in homeotropic cells

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    We study the phase diagram of director structures in cholesteric liquid crystals of negative dielectric anisotropy in homeotropic cells of thickness d which is smaller than the cholesteric pitch p. The basic control parameters are the frustration ratio d/p and the applied voltage U. Fluorescence Confocal Polarising Microscopy allows us to directly and unambiguously determine the 3-D director structures. The results are of importance for potential applications of the cholesteric structures, such as switchable gratings and eyewear with tunable transparency based.Comment: Will be published in Physical Review
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